24 completed, 6 terminated, 6 unknown, 1 recruiting. 37 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 37 | Completed 24, Terminated 6, Unknown 6, Recruiting 1 |
Follow Dwarfism: new trials by email Literature Review of Dwarfism trials Research Report on Dwarfism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Levothyroxine Dosing in Neonatal Congenital Hypothyroidism Levothyroxine - Congenital Hypothyroidism | Phase 4 | Completed | Menoufia University | 101 | 2025-11-02 | 2026-08-10 |
| Effects of GH and Lirglutide on AgRP growth hormone and lirglutide, growth hormone, liraglutide - Healthy, Growth Hormone Deficiency | Phase 4 | Recruiting | Columbia University | 40 | 2023-05-01 | 2026-03-04 |
| A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia Recombinant human growth hormone - Achondroplasia | Phase 4 | Completed | Changchun GeneScience Pharmaceutical Co., Ltd. | 39 | 2022-08-20 | 2026-08-06 |
| Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH) Tirosint®-SOL, Levothyroxine Sodium - Congenital Hypothyroidism | Phase 4 | Terminated | IBSA Institut Biochimique SA | 34 | 2022-01-21 | 2026-06-26 |
| Body Composition and Adipose Tissue in HIV Tesamorelin - HIV Lipodystrophy Syndrome, Growth Hormone Deficiency | Phase 4 | Terminated | Columbia University | 6 | 2018-02-07 | 2026-05-19 |
| Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj. Somatropin - Short Stature, Idiopathic, Infant, Small for Gestational Age | Phase 4 | Completed | LG Life Sciences | 116 | 2016-08-11 | 2019-01-03 |
| A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone Deficiency Somatropin - Growth Hormone Deficiency | Phase 4 | Completed | Genentech, Inc. | 82 | 2015-03-31 | 2019-01-08 |
| Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency PEG-somatropin - Growth Hormone Deficiency | Phase 4 | Unknown | Changchun GeneScience Pharmaceutical Co., Ltd. | 600 | 2015-01-01 | 2017-06-16 |
| Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency PEG-somatropin - Growth Hormone Deficiency | Phase 4 | Unknown | Changchun GeneScience Pharmaceutical Co., Ltd. | 900 | 2015-01-01 | 2017-08-15 |
| Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I) PEG-somatropin - Growth Hormone Deficiency | Phase 4 | Unknown | Changchun GeneScience Pharmaceutical Co., Ltd. | 600 | 2014-12-01 | 2017-06-16 |
| Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children PEG-somatropin - Dwarfism, Pituitary | Phase 4 | Unknown | Changchun GeneScience Pharmaceutical Co., Ltd. | 900 | 2014-11-01 | 2014-12-11 |
| Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency PEG-somatropin - Growth Hormone Deficiency | Phase 4 | Unknown | Changchun GeneScience Pharmaceutical Co., Ltd. | 900 | 2014-11-01 | 2017-06-14 |
| An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD) Saizen® solution for injection (referred as Saizen®) - Adult Growth Hormone Deficiency | Phase 4 | Completed | Merck KGaA, Darmstadt, Germany | 78 | 2013-06-01 | 2017-12-02 |
| GH and Cardiovascular Risk Factors Change in daily dosage of Growth Hormone - Growth Hormone Deficiency, Cardiovascular Diseases | Phase 4 | Completed | Amsterdam UMC, location VUmc | 32 | 2013-05-01 | 2014-05-07 |
| Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Growth Hormone - Chronic Myelogenous Leukemia, Short Stature | Phase 4 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 20 | 2013-01-01 | 2013-07-17 |
| First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study Blood sampling - Idiopathic Growth Hormone Deficiency, Turner Syndrome | Phase 4 | Completed | Merck KGaA, Darmstadt, Germany | 458 | 2011-09-01 | 2014-01-16 |
| Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital Hypothyroidism Levothyroxin - Congenital Hypothyroidism | Phase 4 | Completed | Federico II University | 72 | 2011-05-01 | 2022-05-12 |
| Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.) sustained-release recombinant human GH (SR-rhGH) - Growth Hormone Deficiency | Phase 4 | Completed | LG Life Sciences | 132 | 2009-12-01 | 2012-10-05 |
| Aromatase Inhibitor Growth Study: Letrozole vs. Anastrozole Letrozole, Anastrozole - Short Stature | Phase 4 | Completed | Stanford University | 79 | 2009-11-18 | 2021-07-15 |
| Comparison of a Needle-free Injection Method With a Needle-syringe Injection Method T-jet® containing TevTropin®, TevTropin® needle-syringe injection method - Growth Hormone Deficiency | Phase 4 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 52 | 2009-09-01 | 2011-07-25 |
Showing 20 of 37. Sign in to see all of them.
Dwarfism, Pituitary (30) · Congenital Hypothyroidism (3) · Turner Syndrome (3) · Brain Injuries (2) · Brain Injuries, Traumatic (2) · Kidney Failure, Chronic (2) · Achondroplasia (1) · Cardiovascular Diseases (1) · Combined Pituitary Hormone Deficiency (1) · HIV-Associated Lipodystrophy Syndrome (1) · Hypopituitarism (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Metabolic Syndrome (1) · Motor Activity (1)
Bone Diseases (37) · Bone Diseases, Developmental (37) · Musculoskeletal Diseases (37) · Endocrine System Diseases (36) · Bone Diseases, Endocrine (33) · Brain Diseases (30) · Central Nervous System Diseases (30) · Hypothalamic Diseases (30) · Nervous System Diseases (30) · Pituitary Diseases (30) · Hypopituitarism (29) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (15) · Genetic Diseases, Inborn (15) · Congenital Abnormalities (5)
Human Growth Hormone (14) · Growth Hormone (11) · Blood Specimen Collection (3) · Thyroxine (3) · Absorptiometry, Photon (1) · Anastrozole (1) · Arginine (1) · Biopsy (1) · Fluid Therapy (1) · Growth Hormone-Releasing Hormone (1) · Hematologic Tests (1) · Injections (1) · Letrozole (1) · Liraglutide (1) · Referral and Consultation (1)
Changchun GeneScience Pharmaceutical Co., Ltd. (6) · Merck KGaA, Darmstadt, Germany (5) · Pfizer (4) · Columbia University (3) · LG Life Sciences (2) · Novo Nordisk A/S (2) · Amsterdam UMC, location VUmc (1) · Charite University, Berlin, Germany (1) · Children's Hospital Los Angeles (1) · EMD Serono (1) · Federico II University (1) · Genentech, Inc. (1) · IBSA Institut Biochimique SA (1) · Menoufia University (1) · Ohio State University (1)
United States (12) · China (6) · France (6) · Germany (4) · Sweden (4) · United Kingdom (4) · Italy (3) · Spain (3) · Argentina (2) · Australia (2) · Canada (2) · Netherlands (2) · Austria (1) · Czechia (1) · Egypt (1)
Amira Y Al-Uzri, M.D. (1) · Ayman M Arafat, Dr.med. (1) · Chunxiu Gong (1) · E Kirk Neely, MD (1) · Feihong Luo (1) · Feihong Luo, Doctor (1) · Gilles Della Corte (1) · Giuseppe Mautone (1) · Guimei Li (1) · Jin Wu (1) · John C Ausiello, MD (1)
PMID 20372873, PMID 23567489, PMID 24013497, PMID 24406482, PMID 24916642, PMID 25137428, PMID 26340968, PMID 29618660, PMID 29980224, PMID 31908426, PMID 33633687, PMID 34040195, PMID 34045667, PMID 34899612, PMID 35945517, PMID 36034802, PMID 36133316, PMID 38561465
2015 (1), R01DK110771 (1)