93 completed, 22 unknown, 11 recruiting, 4 not yet recruiting. 92 Not applicable, 12 Phase 2, 6 Phase 4, 4 Phase 1, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital PrEP Micro-Intervention for PWUD in Kazakhstan Dgital micro-intervention - Drug Use, HIV | Not applicable | Not yet recruiting | Yale University | 40 | 2027-01-01 | 2026-10-08 |
| Disease Intervention Specialist (DIS) for SUD Substance Use Disorder (SUD), Opioid Use Disorder | Not yet recruiting | Ohio State University | 1200 | 2026-12-01 | 2026-10-15 | |
| Lakota Family Acceptance Project Pilot RCT Adapted Lakota Family Acceptance Program - LGBTQ, Racial Disparities | Not applicable | Not yet recruiting | University of Michigan | 40 | 2026-10-10 | 2026-10-13 |
| Development of a Multilevel HIV Prevention Intervention for the Emergency Department mSYNC - HIV, Drug Use | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 100 | 2026-09-01 | 2026-07-09 |
| Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs Project REACH - Substance Use, Drug Use | Not applicable | Recruiting | University of Minnesota | 121 | 2026-05-06 | 2026-05-19 |
| Lakota Family Acceptance Project Adapted Lakota Family Acceptance Program - LGBTQ, Racial Disparities | Not applicable | Completed | University of Michigan | 21 | 2026-01-20 | 2026-09-01 |
| Reducing Stigma in People Who Inject Drugs (PWID) With HIV Using a Rapid Start Antiretroviral Therapy Intervention (ART) Rapid-Start ART (RS-ART) - Hiv, Drug Use | Not applicable | Recruiting | Yale University | 135 | 2025-11-04 | 2026-09-10 |
| Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation Peer-educator-based network - HIV Infections, Substance Use Disorders | Not applicable | Recruiting | Johns Hopkins University | 360 | 2025-10-28 | 2025-11-10 |
| Family Acceptance Project Online (Pilot RCT) Family Acceptance Project - Online - LGBTQ, Racial Disparities | Phase 2 | Recruiting | University of Michigan | 180 | 2025-04-24 | 2026-02-11 |
| Harm Reduction Services Integrated Harm Reduction Intervention (IHRI) - Drug Use, Substance Abuse | Not applicable | Recruiting | NYU Langone Health | 200 | 2024-11-25 | 2026-08-20 |
| Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries Low dead-space syringes/needles, Hepatitis C Antibody Rapid Diagnostic Test, HIV rapid Diagnostic Test - Drug Use, Hepatitis | Recruiting | Médecins du Monde | 2400 | 2024-09-13 | 2026-10-09 | |
| Active Pharmacovigilance Study of the Medicine Rinvoq™ (Upadacitinib) Upadacitinib - Inflammatory Disease, Drug Side Effect | Unknown | Universidade do Porto | 150 | 2024-07-01 | 2024-07-15 | |
| Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents Native PATHS - Alcohol Drinking, Tobacco Use | Not applicable | Unknown | University of Rhode Island | 60 | 2024-06-17 | 2024-06-05 |
| Social Responses to Stigma Qualitative interview, participant observation - Stigma, Social, Drug Use | Unknown | King's College London | 200 | 2024-05-01 | 2024-03-05 | |
| NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC Nanoliposomal Irinotecan+Oxaliplatin +Capecitabine+Cadonilimab - Nanoliposomal Irinotecan, Cadonilimab | Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 30 | 2024-04-17 | 2024-12-24 |
| Effect of Dexmedetomidine on Oxygenation and Lung Mechanics GROUP Dexmedetomidine, GROUP B, GROUP C - Drug Use, Dexmedetomidine | Not applicable | Unknown | Cairo University | 176 | 2024-04-01 | 2024-04-10 |
| Organization-level Youth Engagement Approach for Substance Misuse Prevention Organization-level Youth Engagement prevention strategy - Drug Use, Substance Use | Not applicable | Completed | Wake Forest University Health Sciences | 43 | 2024-03-14 | 2025-10-31 |
| Families With Pride ("Familias Con Orgullo"). Families with Pride ("Familias con Orgullo") - Depression, Drug Use | Not applicable | Recruiting | University of Miami | 306 | 2024-03-11 | 2026-05-13 |
| A Model for Drug Concentration Prediction of Vancomycin no intervention - Critical Illness, Infections | Unknown | Peking Union Medical College Hospital | 401 | 2024-03-01 | 2024-05-28 | |
| E-PAUse: Encouraging Proper Antibiotic Use in Outpatient Setting comprehensive multi-component interventions - Drug Use | Not applicable | Active not recruiting | Hamad Medical Corporation | 100000 | 2023-12-01 | 2025-04-03 |
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Substance-Related Disorders (22) · Alcohol Drinking (20) · Depression (12) · Acquired Immunodeficiency Syndrome (11) · HIV Infections (10) · Hepatitis C (8) · Anxiety Disorders (7) · Sexual Behavior (7) · Alcoholism (6) · Adolescent Behavior (5) · Drug-Related Side Effects and Adverse Reactions (5) · Medication Adherence (5) · Harm Reduction (4) · Opioid-Related Disorders (4) · Behavior, Addictive (3)
Behavior (52) · Mental Disorders (42) · Chemically-Induced Disorders (38) · Infections (32) · Communicable Diseases (30) · Virus Diseases (27) · Blood-Borne Infections (26) · RNA Virus Infections (25) · Urogenital Diseases (24) · Drinking Behavior (23) · Genital Diseases (22) · Immune System Diseases (19) · Sexually Transmitted Diseases (19) · Lentivirus Infections (18) · Retroviridae Infections (18)
Ethanol (2) · Tablets (2) · bictegravir, emtricitabine, tenofovir alafenamide, drug combination (2) · Acyclovir (1) · Amlodipine (1) · Biological Products (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Buprenorphine (1) · Buprenorphine, Naloxone Drug Combination (1) · COVID-19 Testing (1) · Cefixime (1) · Control Groups (1) · Counseling (1) · Crisis Intervention (1)
University of Michigan (6) · Johns Hopkins Bloomberg School of Public Health (5) · University of California, Los Angeles (5) · University of Miami (5) · ANRS, Emerging Infectious Diseases (3) · Boston Medical Center (3) · Hunter College of City University of New York (3) · Johns Hopkins University (3) · Treatment Research Institute (3) · University of Maryland, College Park (3) · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (2) · Hasselt University (2) · Medical University of South Carolina (2) · NYU Langone Health (2) · PT. Kimia Farma (Persero) Tbk (2)
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Adam C Brooks, PhD (3) · Frans D Suyatna (3) · Guillermo Prado, PhD (3) · Lillian Gelberg, MD, MSPH (3) · Tyrel J Starks, PhD (3) · Allison Barlow, PhD (2) · Frederick L Altice, MD (2) · Heidi Resnick, Ph.D. (2) · Katie Edwards, PhD (2) · Leslie Leve, PhD (2) · Oluwaseun Falade-Nwulia, MBBS, MPH (2) · Adeel A. Butt, MBBS, MS (1) · Andrea R Thurman, MD (1)
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R34MH134937 (2), 2017 (1), F32MH138253 (1), K01DA048201 (1), K23DA036008 (1), K23DA039179 (1), K23DA041901 (1), K23DA060719 (1), K24DA046569 (1), K24MH086814 (1), P30MH062294 (1), P50DA035763 (1), R01AA016102 (1), R01AA028201 (1), R01AA028507 (1)