34 completed, 28 recruiting, 22 unknown, 10 not yet recruiting. 107 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 107 | Completed 34, Recruiting 28, Unknown 22, Not yet recruiting 10, Active not recruiting 5, Terminated 5, Withdrawn 3 |
Follow Disease Progression: new trials by email Literature Review of Disease Progression trials Research Report on Disease Progression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Silver Nitrate Cauterization vs Conservative Management in Tympanic Membrane Perforation Closure 50% Silver Nitrate Cauterization - Tympanic Membrane Perforation | Not applicable | Not yet recruiting | Muhammad Ali Javed | 56 | 2027-01-01 | 2026-09-22 |
| MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training Generative AI-integrated Blended Simulation, High Fidelity Simulation - Clinical Reasoning in Nursing Education, Virtual Simulation | Not applicable | Not yet recruiting | National University of Singapore | 200 | 2026-10-12 | 2026-10-21 |
| Hospital-Onset Sepsis Systematic Detection and Structured Interventions Algorithm-triggered sepsis alert with structured critical care team activation - Sepsis, Deterioration, Clinical | Not applicable | Not yet recruiting | Patricks Lyons | 3700 | 2026-10-01 | 2026-09-04 |
| The Orientation Intervention to Rapid Response Teams (ORIENT-RRT) Study: A Quasi-Experimental Study Orientation day with rapid response nurse - Deterioration, Clinical | Not applicable | Recruiting | University of Colorado, Denver | 300 | 2026-09-28 | 2026-10-27 |
| Supervised Exercise During Neoadjuvant Chemotherapy for Breast Cancer Supervised exercise - Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Neoplasm Malignant Female | Not applicable | Not yet recruiting | King Hamad University Hospital, Bahrain | 80 | 2026-09-01 | 2026-08-13 |
| Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm Validation Continuous vital sign monitoring - Postoperative Care, Deterioration, Clinical | Not applicable | Not yet recruiting | Eske Kvanner Aasvang | 100 | 2026-05-28 | 2026-06-16 |
| Different Approaches for Alveolar Ridge Preservation Bone Allograft + Autologous Platelet-Rich Fibrin (PRF) Membrane, Control group, Bone Allograft + Resorbable Guided Bone Regeneration Membrane - Alveolar Ridge Resorption | Not applicable | Recruiting | Danae A. Apatzidou | 51 | 2026-05-01 | 2026-09-25 |
| Wireless Assessment of Respiratory and Circulatory Distress - Europe WARD-CSS (Wireless Assessment of Respiratory and Circulatory Distress - Clinical Support System) - Patient Deterioration, Patient Monitoring | Not applicable | Not yet recruiting | Eske Kvanner Aasvang | 1240 | 2026-03-16 | 2026-03-05 |
| Evolution of Lesions in Repeated Biparametric Prostate Magnetic Resonance Imaging MRI - Prostate Cancer (Diagnosis) | Not applicable | Recruiting | University of Eastern Finland | 100 | 2026-02-23 | 2026-02-24 |
| Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-Pediatric PICTURE-Pediatric scores and alerts, Control Arm - Scores and alerts hidden - Clinical Deterioration | Not applicable | Recruiting | University of Michigan | 375 | 2026-02-09 | 2026-03-05 |
| Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission Home-based Clinical Assessment and Treatment - Nursing Homes Residents, Deterioration, Clinical | Not applicable | Recruiting | Copenhagen University Hospital at Herlev | 9000 | 2026-02-01 | 2026-09-02 |
| Lifestyle, Exercise, And Nutrition (LEAN) Trial on Pathologic Complete Response in TNBC Exercise and Medical Nutrition - Triple Negative Breast Cancer | Not applicable | Recruiting | Yale University | 160 | 2025-10-17 | 2026-09-25 |
| Neoadjuvant Chemotherapy Combined With Preoperative Radiotherapy for Locally Advanced Breast Cancer preoperative radiotherapy - Breast Cancer | Not applicable | Not yet recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 50 | 2025-10-01 | 2025-09-10 |
| Off-script Diagnosis & Differential Diagnosis (D&D) Training and Residents' Stroke Knowledge Off-script diagnosis & differential diagnosis (D&D) training - Stroke, Acute, Educational Problems | Not applicable | Completed | Peking Union Medical College Hospital | 22 | 2025-06-20 | 2026-08-12 |
| FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer FDG-PET/CT, CE-CT - Metastatic Breast Cancer, Response Monitoring | Not applicable | Recruiting | Odense University Hospital | 420 | 2025-04-02 | 2026-02-20 |
| The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL) the labour care guide (LCG) - Labor Dystocia, Labor Complication | Not applicable | Recruiting | Ostfold Hospital Trust | 23650 | 2025-04-01 | 2025-04-04 |
| Oral Tacrolimus vs Dexamethasone Micro-pulse Therapy in Pediatric Rapidly Progressing Vitiligo: A Multicenter RCT Tacrolimus, Dexamethasone - Vitiligo, Child | Not applicable | Recruiting | Xijing Hospital | 90 | 2025-04-01 | 2025-06-19 |
| Diuretic Testing in Chronic Kidney Disease Diuretic Testing - Kidney Disease, Chronic | Not applicable | Recruiting | Erasmus Medical Center | 86 | 2025-04-01 | 2025-08-07 |
| THE EFFECTS OF AEROBİC EXERCİSE ON NEUROVASCULAR UNİT AND CLİNİCAL PROGRESSİON MARKERS İN INDİVİDUALS WİTH MULTİPLE SCLEROSİS aerobic exercise intervention - Multiple Sclerosis | Not applicable | Completed | Lokman Hekim University | 30 | 2025-02-01 | 2026-01-08 |
| Multicomponent Exercise to Prevent Hospitalization-Associated Disability Behavioral: Exercise - Clinical Deterioration | Not applicable | Recruiting | Fundacion Miguel Servet | 300 | 2025-02-01 | 2026-07-16 |
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Pathologic Complete Response (25) · Clinical Deterioration (21) · Breast Neoplasms (10) · Rectal Neoplasms (9) · Recurrence (9) · Motor Activity (6) · Parkinson Disease (5) · Urinary Bladder Neoplasms (5) · HIV Infections (4) · Renal Insufficiency, Chronic (4) · Carcinoma, Non-Small-Cell Lung (3) · Carcinoma, Renal Cell (3) · Melanoma (3) · Prostatic Neoplasms (3)
Disease Attributes (107) · Pathologic Processes (107) · Pathological Conditions, Signs and Symptoms (107) · Neoplasms (34) · Neoplasms by Site (32) · Urogenital Diseases (24) · Male Urogenital Diseases (18) · Female Urogenital Diseases and Pregnancy Complications (17) · Female Urogenital Diseases (16) · Skin and Connective Tissue Diseases (15) · Urologic Diseases (15) · Nervous System Diseases (13) · Skin Diseases (13) · Behavior (11)
Cholecalciferol (3) · Standard of Care (3) · Exercise (2) · Fatty Acids, Omega-3 (2) · Fish Oils (2) · Magnetic Resonance Spectroscopy (2) · Metronidazole (2) · Omacor (2) · Tenofovir (2) · 3-fluoro-2-(4-((2-nitro-1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)propan-1-ol (1) · Azithromycin (1) · Cell-Free Nucleic Acids (1) · Chemoradiotherapy (1) · Cognitive Remediation (1) · Colchicine (1)
Mansoura University (4) · Assistance Publique - Hôpitaux de Paris (3) · Brigham and Women's Hospital (2) · Centre Leon Berard (2) · Eske Kvanner Aasvang (2) · Fundacion Miguel Servet (2) · Gilead Sciences (2) · Maastricht Radiation Oncology (2) · Shanghai Zhongshan Hospital (2) · Stanford University (2) · The Netherlands Cancer Institute (2) · Universidad Complutense de Madrid (2) · University Hospital Bispebjerg and Frederiksberg (2) · AgileMD, Inc. (1) · Amsterdam UMC, location VUmc (1)
United States (18) · France (10) · China (9) · Denmark (8) · Netherlands (8) · Spain (6) · Egypt (4) · Italy (4) · Turkey (Türkiye) (4) · United Kingdom (4) · Belgium (3) · Canada (3) · Portugal (3) · Argentina (2) · Australia (2)
Amr A Elsawy (2) · Abdelwahab Hashem, Msc (1) · Ahmed Elshal, MD (1) · Ahmed Mosbah, MD, Phd (1) · Alexander H Kirsch, MD (1) · Alice Nieuwboer, PhD (1) · Andrew JE Seely, MD, PhD, FRCSC (1) · Andrew Kneebone, MBBS (1) · Anita Simonds (1) · Bart Neyns, Md Phd (1) · Bedir Ali-Eldeen, MD, Phd (1) · Benoit H Mulsant, MD (1) · Bo Ejbjerg, MD, PhD (1)
PMID 15002082, PMID 15586136, PMID 16192247, PMID 20855414, PMID 23440923, PMID 25896862, PMID 26731191, PMID 26850040, PMID 26879805, PMID 27538418, PMID 27856480, PMID 27988219, PMID 28077587, PMID 28114897, PMID 29546247, PMID 29599185, PMID 30721294, PMID 30897090, PMID 31842993, PMID 31915173, PMID 32323313, PMID 32929463, PMID 33119047, PMID 33789551, PMID 33846084, PMID 34023224, PMID 34043525, PMID 34474649, PMID 34749008, PMID 35599143, PMID 35679030, PMID 35771552, PMID 35818122, PMID 36087608, PMID 36892723, PMID 37161377, PMID 37271418, PMID 37316784, PMID 37316919, PMID 38380992, PMID 38619713, PMID 38918695, PMID 39476073, PMID 40455621, PMID 40528226, PMID 40742731, PMID 40997056, PMID 41644641, PMID 42203570, PMID 42300721
2018 (1), 2023 (1), R01EY021900 (1), R01EY022663 (1)