65 completed, 13 withdrawn, 11 terminated, 9 recruiting. 17 Not applicable, 15 Phase 1, 15 Phase 2, 4 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Registry Maastro Applicator Rectal Cancer | Recruiting | Maastricht Radiation Oncology | 999 | 2026-03-23 | 2026-10-09 | |
| Lab Research Using Mini-tumors to Study Prostate Cancer Treatments HDR brachytherapy, Diagnostic biopsy - Prostate Cancer, Prostate Cancer Metastatic Disease | Recruiting | Maastricht Radiation Oncology | 600 | 2026-03-15 | 2026-04-23 | |
| Re-induction of a Systemic Immune Response in Metastatic or Locally Recurrent Lung Cancer Radiation - Lung Cancer Stage IV | Phase 2 | Withdrawn | Maastricht Radiation Oncology | 2024-12-01 | 2024-09-19 | |
| Feasibility of the Maastro Applicator in Rectal Cancer Maastro applicator - Rectal Cancer, Feasibility | Not applicable | Active not recruiting | Maastricht Radiation Oncology | 10 | 2024-08-27 | 2025-08-14 |
| In Vivo Treatment Verification of Brachytherapy External imaging panel - Brachytherapy | Recruiting | Maastricht Radiation Oncology | 100 | 2024-02-29 | 2025-05-09 | |
| Precision Radiation Treatment for Epilepsy (PRECISION) LINAC-based Stereotactic Radiotherapy - Epilepsy | Not applicable | Active not recruiting | Maastricht Radiation Oncology | 94 | 2023-12-01 | 2025-08-14 |
| The Addition of Chloroquine to Chemoradiation for Glioblastoma, Chloroquine - Glioblastoma, Astrocytoma, Grade IV | Phase 2 | Withdrawn | Maastricht Radiation Oncology | 2023-11-10 | 2023-11-18 | |
| Standard of Care Lifestyle Support for Stage III NSCLC Patients Lifestyle advice - Non Small Cell Lung Cancer | Withdrawn | Maastricht Radiation Oncology | 2023-08-01 | 2023-09-06 | ||
| The Effect of 360° Virtual Reality Movies on Fear and Anxiety Questionnaire: SPIRIT, Questionnaire: HADS, Questionnaire: QSC-R23 - Fear, Anxiety | Not applicable | Completed | Maastricht Radiation Oncology | 292 | 2023-06-16 | 2025-10-02 |
| Lung Cancer Organoids and Patient Derived Tumor Xenografts Tissue and blood - Lung Cancer | Active not recruiting | Maastricht Radiation Oncology | 600 | 2022-10-05 | 2026-07-13 | |
| Developing Breast (Cancer) Organoids Not an extra intervention, tissue taken in routine practice will be used. - Breast Cancer | Recruiting | Maastricht Radiation Oncology | 60 | 2022-09-01 | 2026-05-12 | |
| DETECT: Target Volume for Rectal Endoluminal Radiation Boosting Ultrasound, Rectoscopy, Scan, e.g. CT (resection specimen) - Rectal Cancer | Recruiting | Maastricht Radiation Oncology | 50 | 2022-08-16 | 2026-10-09 | |
| Effect of stRess and exeRcize on the Outcome After Chemo-Radiation Smartwatch, Serum Cortisol, Questionnaires - Glioblastoma (GBM) | Completed | Maastricht Radiation Oncology | 42 | 2022-06-01 | 2026-03-04 | |
| A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors Low-grade Glioma, High Grade Glioma | Recruiting | Maastricht Radiation Oncology | 50 | 2022-05-01 | 2026-01-27 | |
| Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI Head and Neck Carcinoma | Completed | Maastricht Radiation Oncology | 900 | 2022-03-22 | 2026-10-09 | |
| Spatial Location of Breast Cancer Local Recurrence After Mastectomy Mastectomy - Breast Cancer | Unknown | Maastricht Radiation Oncology | 170 | 2021-09-01 | 2023-11-14 | |
| ARtificial Intelligence for Gross Tumour vOlume Segmentation Radiotherapy - Lung Cancer | Active not recruiting | Maastricht Radiation Oncology | 2000 | 2021-07-01 | 2026-10-15 | |
| Patient-derived Glioma Stem Cell Organoids Tumor biopsy - Glioblastoma | Active not recruiting | Maastricht Radiation Oncology | 60 | 2021-04-10 | 2026-10-13 | |
| PREselection of Patients at Risk for COgnitive DEcline After Radiotherapy Using Advanced MRI PRECODE-MRI - Meningioma | Active not recruiting | Maastricht Radiation Oncology | 67 | 2021-04-08 | 2026-07-07 | |
| Immune Profiling of Stage III Non-small Cell Lung Cancer Patients Treated With Concurrent Chemoradiation and Adjuvant Durvalumab: A Prospective Observational Phase II Trial Carcinoma, Non-Small-Cell Lung | Active not recruiting | Maastricht Radiation Oncology | 45 | 2021-04-01 | 2026-01-27 |
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Carcinoma, Non-Small-Cell Lung (25) · Lung Neoplasms (12) · Breast Neoplasms (9) · Head and Neck Neoplasms (9) · Glioblastoma (8) · Rectal Neoplasms (8) · Neoplasms (7) · Prostatic Neoplasms (5) · Small Cell Lung Carcinoma (5) · Astrocytoma (4) · Esophageal Neoplasms (4) · Glioma (4) · Hypoxia (4) · Neoplasm Metastasis (4) · Uterine Cervical Neoplasms (4)
Radiotherapy (9) · 3-fluoro-2-(4-((2-nitro-1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)propan-1-ol (4) · Chloroquine (4) · Surgical Procedures, Operative (3) · Surveys and Questionnaires (3) · Biopsy (2) · Blood Specimen Collection (2) · Injections (2) · Interviews as Topic (2) · L19-IL2 immunocytokine (2) · Nelfinavir (2) · Radiation (2) · X-Rays (2) · 3-(4-(2-fluoroethoxy)phenyl)-2-(3-methyl-2-(4-((2-sulfamoylbenzo(d)thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)butanamido)propanoic acid (1) · Ambulatory Care Facilities (1)
Netherlands (101) · United States (3) · Germany (2) · Italy (2) · Belgium (1) · Canada (1) · France (1) · India (1) · South Africa (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Dirk De Ruysscher, MD, PhD (11) · Philippe Lambin, MD, PhD (10) · Dirk De Ruysscher, MD,PhD (3) · Anne-Marie Dingemans, MD, PhD (2) · Brigitta Baumert, MD PhD (2) · Danielle Eekers (2) · Dirk De Ruysscher, MD PhD (2) · Dirk De Ruysscher, PHD (2) · Esther Troost, PhD (2) · Marc Vooijs, MD, PhD (2) · Marc Vooijs, Prof. Dr. (2) · Philippe Lambin, prof (2) · A Mendez Romero (1) · A Voogd (1)
PMID 20888135, PMID 23522151, PMID 24044794, PMID 15234029, PMID 16520474, PMID 17562346, PMID 21306971, PMID 22071782, PMID 22194025, PMID 22217243, PMID 22608261, PMID 22982655, PMID 23211715, PMID 23429647, PMID 23433435, PMID 23891088, PMID 24309199, PMID 24621620, PMID 24892406, PMID 26338178, PMID 27535748, PMID 28743240, PMID 29414140, PMID 29651598, PMID 30663068, PMID 31733490, PMID 34738049, PMID 34806396, PMID 35952707, PMID 38773643, PMID 39912580, PMID 40252811, PMID 40597116, PMID 42372742