9 completed. 9 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Completed 9 |
Follow Dilatation, Pathologic: new trials by email Literature Review of Dilatation, Pathologic trials Research Report on Dilatation, Pathologic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients MydCombi Device, MydCombi Drug - Dilation, Pupil Reaction Absent | Phase 4 | Completed | University of California, San Francisco | 70 | 2024-10-01 | 2026-09-22 |
| Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution - Procedural Pain, Buprenorphine | Phase 4 | Completed | University of California, San Diego | 57 | 2020-05-28 | 2023-08-01 |
| The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients sacubitril/valsatran, valsartan, placebo to valsartan - Heart Failure | Phase 4 | Completed | Novartis Pharmaceuticals | 55 | 2018-07-05 | 2024-01-05 |
| Gabapentin for Pain Management During Dilation and Evacuation Gabapentin, Placebo - Pain | Phase 4 | Completed | Medstar Health Research Institute | 130 | 2017-05-26 | 2020-06-18 |
| 12 Versus 20 mL PCB for D&E Cervical Prep 12 mL paracervical block, 20 mL paracervical block - Pain | Phase 4 | Completed | Stanford University | 96 | 2017-01-01 | 2024-01-23 |
| Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients. sacubitril/valsartan (LCZ696), enalapril, matching placebo sacubitril/valsartan (LCZ696) - Heart Failure, Reduced Ejection Fraction | Phase 4 | Completed | Novartis Pharmaceuticals | 140 | 2016-12-16 | 2021-10-07 |
| 24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E Vaginal Misoprostol, Buccal Misoprostol - Abortion, Second Trimester | Phase 4 | Completed | Virginia Commonwealth University | 70 | 2016-11-19 | 2018-07-18 |
| Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation Lidocaine, placebo comparator - Pain Alleviation, Dilatation and Evacuation | Phase 4 | Completed | Sheba Medical Center | 134 | 2016-07-01 | 2020-05-27 |
| 'Levonorgestrel IUD Insertion After D&E Procedure Levonorgestrel IUD - Contraceptive Usage | Phase 4 | Completed | University of Pittsburgh | 93 | 2007-03-01 | 2017-05-09 |
Pain (3) · Heart Failure (2) · Hypertrophy, Left Ventricular (2) · Contraception Behavior (1) · Heart Failure, Systolic (1) · Motor Activity (1) · Pain, Procedural (1) · Pupil Disorders (1)
Pathological Conditions, Anatomical (9) · Pathological Conditions, Signs and Symptoms (9) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Behavior (2) · Cardiomegaly (2) · Cardiovascular Diseases (2) · Heart Diseases (2) · Hypertrophy (2) · Eye Diseases (1) · Nervous System Diseases (1) · Pain (1) · Reproductive Behavior (1)
Lidocaine (2) · Valsartan (2) · sacubitril (2) · Anesthesia, Obstetrical (1) · Buprenorphine (1) · Enalapril (1) · Gabapentin (1) · Levonorgestrel (1) · Misoprostol (1) · sacubitril and valsartan sodium hydrate drug combination (1)
Novartis Pharmaceuticals (2) · Medstar Health Research Institute (1) · Sheba Medical Center (1) · Stanford University (1) · University of California, San Diego (1) · University of California, San Francisco (1) · University of Pittsburgh (1) · Virginia Commonwealth University (1)
United States (7) · Finland (1) · Israel (1)
Frances Casey, MD (1) · Heather Hohmann, MD (1) · Julius Oatts, MD (1) · Nicole Economou, MD (1) · Sheila K Mody, MD, MPH (1)
PMID 32978755, PMID 34352829, PMID 36243129, PMID 41338301
2017 (1)