49 unknown. 49 Phase 2, 13 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 49 | Unknown 49 |
| Phase 1 | 13 | Unknown 13 |
| Phase 3 | 1 | Unknown 1 |
Follow Demyelinating Diseases: new trials by email Literature Review of Demyelinating Diseases trials Research Report on Demyelinating Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate IMC-002 in Neuromyelitis Optica Spectrum Disorder (NMOSD) Patients IMC-002, mycophenolate mofetil， MMF - Neuromyelitis Optica Spectrum Disorder (NMOSD) | Phase 1 / Phase 2 | Unknown | ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd. | 116 | 2024-10-10 | 2024-08-16 |
| FcRn Antagonists (Efgartigimod) for Acute NMOSD Attack Efgartigimod Alfa Injection, High-dose intravenous methylprednisolone - Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder | Phase 2 | Unknown | Tianjin Medical University General Hospital | 63 | 2024-07-05 | 2024-07-11 |
| FMT for MS Patients Fecal Microbial Transplants - Multiple Sclerosis | Phase 2 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 34 | 2023-06-01 | 2022-10-25 |
| A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML CE-VST01-JC - Progressive Multifocal Leukoencephalopathy | Phase 2 | Unknown | Cellevolve Bio Inc | 60 | 2023-02-01 | 2022-09-16 |
| IMCY-0141 Safety and Efficacy in Multiple Sclerosis - ISEMIS Study IMCY-0141, Placebo, Dimethyl Fumarate - Multiple Sclerosis, Relapsing-Remitting | Phase 1 / Phase 2 | Unknown | Imcyse SA | 150 | 2022-04-12 | 2024-03-08 |
| Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients MetFORMIN 1000 Mg Oral Tablet, Interferon beta-1a - Multiple Sclerosis | Phase 2 | Unknown | German University in Cairo | 80 | 2022-02-01 | 2023-03-20 |
| Hydroxychloroquine and Indapamide in SPMS Hydroxychloroquine Pill, Indapamide Pill - Multiple Sclerosis, Secondary Progressive | Phase 2 | Unknown | University of Calgary | 35 | 2021-10-01 | 2022-05-18 |
| Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis IMU-838, Placebo matching IMU-838 - Multiple Sclerosis | Phase 2 | Unknown | Immunic AG | 450 | 2021-09-30 | 2024-04-29 |
| Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis tolebrutinib 60mg, tolebrutinib 120mg - Multiple Sclerosis | Phase 2 | Unknown | National Institute of Neurological Disorders and Stroke (NINDS) | 12 | 2021-04-15 | 2024-08-13 |
| Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 PurWet, FurFat, PurApo - Sequelae of; Infection, Post Infection Glomerulonephritis | Phase 1 / Phase 2 | Unknown | All Natural Medicine Clinic, LLC | 2000 | 2021-03-01 | 2021-05-26 |
| A Phase 2 Study of Orelabrutinib in Patients With Relapsing-Remitting Multiple Sclerosis placebo, orelabrutinib - Relapsing Remitting Multiple Sclerosis | Phase 2 | Unknown | Beijing InnoCare Pharma Tech Co., Ltd. | 160 | 2021-03-01 | 2023-04-21 |
| Famciclovir in Multiple Sclerosis Famciclovir - Multiple Sclerosis | Phase 2 | Unknown | Queen Mary University of London | 30 | 2020-11-25 | 2022-03-17 |
| A Study of NeuroVax™, a Novel Therapeutic TCR Peptide Vaccine for SPMS of Multiple Sclerosis NeuroVax, IFA Incomplete Freund's Adjuvant - Multiple Sclerosis | Phase 2 | Unknown | Immune Response BioPharma, Inc. | 150 | 2020-03-09 | 2020-03-11 |
| A Study of NeuroVax™, a Therapeutic TCR Peptide Vaccine for SPMS of Multiple Sclerosis NeuroVax, IFA Placebo - Secondary Progress Multiple Sclerosis, Multiple Sclerosis | Phase 2 / Phase 3 | Unknown | Immune Response BioPharma, Inc. | 200 | 2020-03-09 | 2020-03-11 |
| To Study the Pathophysiological Features of Multiple Sclerosis 18F-PM-PBB3 - Multiple Sclerosis, Neurofilament Light Chain | Phase 1 / Phase 2 | Unknown | Chang Gung Memorial Hospital | 38 | 2020-02-20 | 2020-01-27 |
| Transcranial Magnetic Stimulation (TMS) in Multiple Sclerosis Transcranial Magnetic Stimulation (TMS), Placebos - Multiple Sclerosis | Phase 1 / Phase 2 | Unknown | Maimónides Biomedical Research Institute of Córdoba | 90 | 2019-10-01 | 2019-08-21 |
| Comparison of the Efficacy and Safety of Immunoadsorption and Plasma Exchange for Acute Attack of Refractory Neuromyelitis Optica Spectrum Disorders blood purification equipment - Neuromyelitis Optica Spectrum Disorder | Phase 2 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 144 | 2019-09-01 | 2019-08-22 |
| Treatment of PD-1 Inhibitor in AIDS-associated PML Pembrolizumab - Progressive Multifocal Leukoencephalopathy, AIDS | Phase 2 | Unknown | First Affiliated Hospital of Zhejiang University | 10 | 2019-08-20 | 2019-09-20 |
| Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury Nerve Growth Factor, Edaravone, Combination of vitamin B1, B6, C, E and mecobalamine - Alcohol-induced Brain Injury | Phase 2 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 150 | 2019-06-30 | 2020-10-27 |
| A Proof of Concept Study With Rituximab in Patients With CIDP Not Responding to Conventional Immune Therapy Rituximab - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Phase 2 | Unknown | Istituto Clinico Humanitas | 20 | 2019-06-01 | 2023-05-26 |
Showing 20 of 49. Sign in to see all of them.
Multiple Sclerosis (33) · Multiple Sclerosis, Chronic Progressive (8) · Multiple Sclerosis, Relapsing-Remitting (8) · Neuromyelitis Optica (4) · Acquired Immunodeficiency Syndrome (2) · Anxiety Disorders (2) · Bipolar Disorder (2) · Depression (2) · Leukoencephalopathy, Progressive Multifocal (2) · Sleep Initiation and Maintenance Disorders (2) · Stress Disorders, Post-Traumatic (2) · Adrenoleukodystrophy (1) · Ageusia (1) · Amyotrophic Lateral Sclerosis (1) · Anemia, Sickle Cell (1)
Nervous System Diseases (49) · Immune System Diseases (46) · Autoimmune Diseases (45) · Autoimmune Diseases of the Nervous System (45) · Demyelinating Autoimmune Diseases, CNS (43) · Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (13) · Disease Attributes (12) · Chronic Disease (11) · Multiple Sclerosis (7) · Eye Diseases (6) · Cranial Nerve Diseases (5) · Optic Nerve Diseases (5) · Brain Diseases (4)
Interferon beta-1a (3) · NeuroVax vaccine (2) · 4-Aminopyridine (1) · Cholecalciferol (1) · Complementary Therapies (1) · Constraint Induced Movement Therapy (1) · Deep Brain Stimulation (1) · Dexrazoxane (1) · Dimethyl Fumarate (1) · Edaravone (1) · Eosinophil Peroxidase (1) · Erythropoietin (1) · Estriol (1) · Famciclovir (1) · HIV-1 immunogen, incomplete Freund's adjuvant (1)
Immune Response BioPharma, Inc. (2) · Novo Cellular Medicine Institute LLP (2) · S. Andrea Hospital (2) · Sheba Medical Center (2) · AlJohara M AlQuaiz, M.D. (1) · All Natural Medicine Clinic, LLC (1) · Antonio Uccelli (1) · Beijing InnoCare Pharma Tech Co., Ltd. (1) · Cantonal Hospital of St. Gallen (1) · Cellevolve Bio Inc (1) · Chaitanya Hospital, Pune (1) · Chang Gung Memorial Hospital (1) · Clinique de sclérose en plaques et neuromusculaire de l'Outaouais (1) · Copenhagen University Hospital, Rigshospitalet (1) · Daval International Limited (1)
United States (11) · China (5) · Italy (4) · Canada (3) · Germany (3) · India (3) · Israel (3) · United Kingdom (3) · Denmark (2) · Moldova (2) · Poland (2) · Switzerland (2) · Trinidad and Tobago (2) · Ukraine (2) · Austria (1)
Carlo Pozzilli, MD (2) · Dr. Bill Brashier, M.D. (2) · Richard M Bartholomew, Ph.D (2) · AlJohara M AlQuaiz, M.D (1) · Anat Achiron, MD PhD (1) · Anat Achiron, Prof. (1) · Andrew Chan, PD Dr. (1) · Biao Zhu, PhD (1) · Bruno Bonetti, MD (1) · Daniel S Reich, M.D. (1) · Dr. Ryan O Lakin, MD JD (1) · Fabiana Marinelli, MD (1) · Fritz Leutmezer, MD (1)
PMID 11231629, PMID 11399225, PMID 12542793, PMID 15864738, PMID 18565456, PMID 19892975, PMID 20445531, PMID 20937945, PMID 23845948, PMID 23966770, PMID 23982748, PMID 24759263, PMID 25442786, PMID 25546364, PMID 26467901, PMID 26762672, PMID 27995531, PMID 28148629, PMID 29668399, PMID 29668401, PMID 30171655, PMID 31072380, PMID 32255785, PMID 32380977, PMID 32500374, PMID 32849212, PMID 35078125, PMID 35487034, PMID 35499744, PMID 38049955, PMID 38070031, PMID 38131621, PMID 38729746