750 completed, 251 unknown, 166 recruiting, 77 not yet recruiting. 1389 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1389 | Completed 750, Unknown 251, Recruiting 166, Not yet recruiting 77, Active not recruiting 58, Terminated 45, Withdrawn 20, Enrolling by invitation 19, Suspended 3 |
Follow Demyelinating Diseases: new trials by email Literature Review of Demyelinating Diseases trials Research Report on Demyelinating Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Vigorous Versus Low Intensity Cool Room Treadmill Training in People with Multiple Sclerosis Body-weight supported treadmill training in a room cooled to 16°C - Multiple Sclerosis, Neurological Rehabilitation | Not applicable | Withdrawn | Memorial University of Newfoundland | 2030-01-01 | 2024-11-27 | |
| Inductive Therapeutic Exercise in Multiple Sclerosis Experimental: Inductive Therapeutic Exercise (ETI), Control: Sham Inductive Therapeutic Exercise (sham-ETI) - Multiple Sclerosis | Not applicable | Not yet recruiting | Fundación San Juan De Dios | 30 | 2027-10-01 | 2026-10-02 |
| Lentiviral Hematopoietic Stem Cell Gene Therapy for MLD Lentiviral TYF-ARSA correction of patient's autologous HSCs - Metachromatic Leukodystrophy (MLD) | Not applicable | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 10 | 2027-06-01 | 2026-09-01 |
| IT and IV Lentiviral Gene Therapy for X-ALD Intrathecal and intravenous LV gene therapy - X-linked Adrenoleukodystrophy | Not applicable | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-01 | 2026-09-01 |
| Direct Lentiviral Injection Gene Therapy for MLD Intrathecal and intravenous LV gene therapy - Metachromatic Leukodystrophy (MLD) | Not applicable | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 10 | 2027-05-31 | 2026-09-01 |
| Efficacy of Seated Physical Activity INtervention(SPIN) for Wheelchair Users With Multiple Sclerosis SPIN exercise-training, Control Condition (WELL) - Multiple Sclerosis | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 100 | 2027-01-04 | 2026-10-23 |
| Exercise With and Without Cognitive Training Effect of Exercise with and Without Cognitive Training on Gait - Multiple Sclerosis | Not applicable | Not yet recruiting | VA Office of Research and Development | 30 | 2027-01-04 | 2026-03-03 |
| Local Vibration and Ankle Mobilization in Multiple Sclerosis Local Vibration, Ankle Joint Mobilization - Multiple Sclerosis | Not applicable | Not yet recruiting | Gaziantep Islam Science and Technology University | 60 | 2026-12-15 | 2026-10-19 |
| Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis Autologous haemopoietic stem cell transplantation - Multiple Sclerosis | Not applicable | Not yet recruiting | Tianjin Medical University General Hospital | 20 | 2026-12-01 | 2026-10-16 |
| Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis Behavioural intervention for physical activity for multiple sclerosis (BIPAMS) - Multiple Sclerosis, Relapsing-Remitting, Sexual Dysfunction | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 30 | 2026-12-01 | 2025-12-22 |
| [18F]F-DED PET Imaging of Reactive Astrocytes in Multiple Sclerosis [18F]fluorodeprenyl-D2 - Multiple Sclerosis | Not applicable | Not yet recruiting | Parc de Salut Mar | 30 | 2026-12-01 | 2026-09-04 |
| Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care MS Boost, Standard of care - Multiple Sclerosis, Fatigue Syndrome, Chronic | Not applicable | Not yet recruiting | Ad scientiam | 208 | 2026-12-01 | 2025-10-03 |
| Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis. Online wellness course and online exercise platform, Usual Care Group - Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS) | Not applicable | Not yet recruiting | University of Iowa | 118 | 2026-11-15 | 2026-09-28 |
| The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis Moderate-Intensity Continuous Training (MICT), High-Intensity Interval Training (HIIT) - Multiple Sclerosis, High-intensity Interval Training | Not applicable | Not yet recruiting | Hacettepe University | 40 | 2026-11-01 | 2026-09-23 |
| An Online Tailored Cognitive Therapy-Based Intervention for Depression in Multiple Sclerosis: ACTION-MS Online ACTION-MS website - an 8-week cognitive behavioural therapy intervention for depression., The 'Health and Wellbeing in MS' website - Depression and Anxiety Symptoms, Multiple Sclerosis | Not applicable | Not yet recruiting | University of Melbourne | 240 | 2026-11-01 | 2026-10-15 |
| Evaluating the Effects of the EXOPULSE Suit on Mobility, Walking Ability, and Balance in People With Multiple Sclerosis Electrostimulation suit - Multiple Sclerosis | Not applicable | Not yet recruiting | Otto Bock Healthcare Products GmbH | 100 | 2026-11-01 | 2026-10-27 |
| Dual-Task Balance Training in People With Multiple Sclerosis: a Randomized Feasibility Study Dual-task balance training - Multiple Sclerosis | Not applicable | Not yet recruiting | Universita di Verona | 30 | 2026-10-15 | 2026-10-16 |
| The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates - Multiple Sclerosis | Not applicable | Recruiting | Yuzuncu Yil University | 38 | 2026-10-12 | 2026-10-26 |
| Early Symptoms in Multiple Sclerosis: an Investigation Using fMRI and Gait Analysis to Develop Personalized Balance Training for People With Low Disability Vestibular Physical Therapy - Multiple Sclerosis | Not applicable | Not yet recruiting | LIFE - Research and Care Institute - Santa Lucia IRCCS | 30 | 2026-10-01 | 2026-09-04 |
| Physical Activity Intervention for Individuals Newly Diagnosed With MS COM-B-based Physical Activity Behavior Change Intervention - Multiple Sclerosis | Not applicable | Not yet recruiting | University of Illinois at Chicago | 50 | 2026-10-01 | 2026-07-28 |
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