10 completed, 2 terminated, 2 withdrawn. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 10, Terminated 2, Withdrawn 2 |
Follow Dehydration: new trials by email Literature Review of Dehydration trials Research Report on Dehydration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Coconut Water on Hydration Status in Pediatric Population Coconut Water, Oral Electrolytes - Sports Nutrition | Phase 4 | Completed | Universidad de Colima | 34 | 2021-10-15 | 2025-02-21 |
| Intravenous Fluids in Hospitalised Children Plasmalyte Glucos 50 mg/mL, 0.45% saline in 5% dextrose - Hypokalemia, Hyponatremia | Phase 4 | Completed | University of Oulu | 660 | 2016-10-03 | 2019-08-22 |
| Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in EDs in Pakistan Ondansetron, Placebo - Dehydration, Gastroenteritis | Phase 4 | Completed | Dr. Stephen Freedman | 625 | 2014-05-01 | 2018-03-02 |
| Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in EDs in Pakistan Ondansetron, Placebo - Dehydration, Gastroenteritis | Phase 4 | Completed | Dr. Stephen Freedman | 918 | 2014-05-01 | 2018-03-02 |
| An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq) RV5 (Pentavalent Rotavirus Vaccine) - Diarrhea, Gastroenteritis | Phase 4 | Completed | Dennis Clements | 66 | 2014-02-01 | 2017-04-21 |
| The Influence of Exercise and Hydration to the Pharmacological Response to Inhaled Terbutalin and Salbutamol in Men Exercise - Healthy | Phase 4 | Withdrawn | Vibeke Backer | 2013-11-01 | 2023-03-01 | |
| Intravenous (IV) Solutions for Dehydration in Children With Gastroenteritis multiple electrolyte solution, saline - Dehydration, Gastroenteritis | Phase 4 | Terminated | Baxter Healthcare Corporation | 100 | 2011-06-01 | 2018-04-26 |
| Efficacy and Time and Resources for Hylenex-facilitated SC Rehydration Versus ORT for Dehydrated Children in the Emergency Department (ED) Oral rehydration fluid, Isotonic hydration fluid and recombinant human hyaluronidase - Dehydration | Phase 4 | Withdrawn | Baxter Healthcare Corporation | 2010-05-01 | 2017-05-08 | |
| Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A) Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution - Dehydration | Phase 4 | Terminated | Baxter Healthcare Corporation | 20 | 2010-05-01 | 2011-10-24 |
| Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics Hylenex - Dehydration, Cardiac Output | Phase 4 | Completed | Vanderbilt University Medical Center | 17 | 2010-02-01 | 2018-02-01 |
| Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase hylenex-facilitated subcutaneous Lactated Ringer's infusion - Dehydration | Phase 4 | Completed | Baxter Healthcare Corporation | 100 | 2008-12-01 | 2011-10-26 |
| Subcutaneous Rehydration Compared to Intravenous Rehydration recombinant human hyaluronidase - Dehydration | Phase 4 | Completed | Halozyme Therapeutics | 148 | 2008-10-01 | 2018-11-07 |
| Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children hyaluronidase (human recombinant)/rehydration fluid - Dehydration | Phase 4 | Completed | Baxter Healthcare Corporation | 52 | 2007-08-01 | 2011-12-01 |
| Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis Standard IV rehydration, Rapid intravenous rehydration (RIVR) - Gastroenteritis, Dehydration | Phase 4 | Completed | The Hospital for Sick Children | 226 | 2006-11-01 | 2018-04-17 |
Gastroenteritis (5) · Diarrhea (3) · Motor Activity (2) · Vomiting (2) · Hypernatremia (1) · Hypokalemia (1) · Hyponatremia (1)
Metabolic Diseases (14) · Nutritional and Metabolic Diseases (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Water-Electrolyte Imbalance (14) · Digestive System Diseases (5) · Gastrointestinal Diseases (5) · Signs and Symptoms (3) · Signs and Symptoms, Digestive (3) · Behavior (2)
Sodium Chloride (3) · Ondansetron (2) · Ringer's Lactate (2) · Saline Solution (2) · Sugars (2) · Electrolytes (1) · Exercise (1) · Fluid Therapy (1) · Glucose (1) · Hyaluronoglucosaminidase (1) · RotaTeq (1)
Baxter Healthcare Corporation (5) · Dr. Stephen Freedman (2) · Dennis Clements (1) · Halozyme Therapeutics (1) · The Hospital for Sick Children (1) · Universidad de Colima (1) · University of Oulu (1) · Vanderbilt University Medical Center (1) · Vibeke Backer (1)
United States (6) · Canada (2) · Pakistan (2) · Denmark (1) · Finland (1) · Mexico (1)
George Harb, MD, MPH (3) · Sajid B Soofi, MD (2) · Stephen Freedman, MD (2) · Zulfiqar Bhutta, MD (2) · Coburn H Allen, MD (1) · Dennis A Clements, MD, PhD (1) · Drew Jones, MD (1) · George E Harb, MD (1) · Stephen B Freedman, MD (1) · Terhi Tapiainen, MD (1) · Thomas J Abramo, MD (1) · Vibeke Backer, Professor (1)
PMID 19805455, PMID 22094316, PMID 23062548, PMID 23993936, PMID 27480410, PMID 30392735, PMID 31694979, PMID 33104176