3 completed, 2 withdrawn, 1 unknown. 6 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 3, Withdrawn 2, Unknown 1 |
| Phase 1 | 4 | Withdrawn 2, Completed 1, Unknown 1 |
Follow Degenerative Spondylolisthesis: new trials by email Literature Review of Degenerative Spondylolisthesis trials Research Report on Degenerative Spondylolisthesis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of RECK in Posterior Spinal Fusion Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo - Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease | Phase 1 / Phase 2 | Withdrawn | University of Maryland, Baltimore | 2025-10-01 | 2025-07-31 | |
| Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion ART352-L - Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Unknown | Ankasa Regenerative Therapeutics, Inc. | 12 | 2020-09-30 | 2020-10-12 |
| Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion NeoFuse, MasterGraft Granules - Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Completed | Mesoblast, Ltd. | 12 | 2010-06-01 | 2020-06-29 |
| Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy NeoFuse, Allograft - Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 2 | Completed | Mesoblast, Ltd. | 24 | 2010-06-01 | 2019-08-16 |
| Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse - Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 2 | Completed | Mesoblast, Ltd. | 24 | 2009-09-01 | 2020-06-29 |
| Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion PLF with autograft, PLF with NeoFuse - Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Withdrawn | Mesoblast, Ltd. | 2008-11-01 | 2020-06-02 |
Intervertebral Disc Degeneration (4) · Spinal Stenosis (4) · Spondylolisthesis (3) · Agnosia (1) · Back Pain (1)
Bone Diseases (6) · Musculoskeletal Diseases (6) · Spinal Diseases (6) · Spondylolysis (3) · Spondylosis (3) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Pain (1) · Perceptual Disorders (1)
Gene Fusion (2) · Spinal Fusion (2) · Transplantation, Autologous (2) · Clonidine (1) · Epinephrine (1) · Ropivacaine (1) · Transplantation, Homologous (1)
Mesoblast, Ltd. (4) · Ankasa Regenerative Therapeutics, Inc. (1) · University of Maryland, Baltimore (1)
United States (5) · Australia (1)
Roger Brown (3) · Donna Skerrett, MD (1)