89 completed. 89 Phase 2, 17 Phase 3, 11 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 89 | Completed 89 |
| Phase 3 | 17 | Completed 17 |
| Phase 1 | 11 | Completed 11 |
Follow Deficiency Diseases: new trials by email Literature Review of Deficiency Diseases trials Research Report on Deficiency Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia Burosumab - Fibrous Dysplasia Of Bone | Phase 2 | Completed | National Institute of Dental and Craniofacial Research (NIDCR) | 12 | 2022-12-07 | 2026-02-02 |
| Vitamin D, Oxidative Stress and Inflammation in Hemodialysis Cholecalciferol - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Ain Shams University | 25 | 2022-05-15 | 2023-02-06 |
| Cholecalciferol Supplementation in Hemodialysis Patients Cholecalciferol - Anemia, Hemodialysis Complication | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2022-05-15 | 2023-06-28 |
| Effectiveness of Vitamin C Supplementation in Treatment of Rickets Vit C - Nutritional Rickets, Bone Turnover Rate Disorder | Phase 2 / Phase 3 | Completed | Cairo University | 88 | 2022-03-01 | 2023-03-08 |
| Nutrition, Immunity, and Covid-19 in Obese People Probiotics, Vitamin D, Placebo - Vitamin D Deficiency, Covid19 | Phase 2 | Completed | Universitas Indonesia | 93 | 2021-07-24 | 2024-06-04 |
| Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency Calcifediol 75mcg, Calcifediol 100mcg, Calcifediol 125mcg - Vitamin D Deficiency, Vitamin D Insufficiency | Phase 2 / Phase 3 | Completed | Faes Farma, S.A. | 674 | 2020-12-23 | 2023-09-15 |
| Daily Vitamin D for Sickle-cell Respiratory Complications Daily oral vitamin D3, 3,333 IU, Monthly oral vitamin D3, 100,000 IU, Placebo oral tablet - Sickle Cell Disease, Anemia, Sickle Cell | Phase 2 | Completed | Columbia University | 58 | 2020-09-15 | 2025-09-24 |
| Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age Burosumab - X-linked Hypophosphatemia (XLH) | Phase 1 / Phase 2 | Completed | Kyowa Kirin Pharmaceutical Development Ltd | 16 | 2020-02-26 | 2024-11-07 |
| Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans cholecalciferol, Standard of Care Prostate Biopsy - collection of 13th core for RNA-seq, Standard of Care Prostate Biopsies at baseline and after one year vitamin D3 supplementation - Prostate Cancer, Vitamin D Deficiency | Phase 2 | Completed | Medical University of South Carolina | 60 | 2019-06-04 | 2025-07-04 |
| Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemia Cholecalciferol 2800 I.U. ml oral drops - Acute Myeloid Leukemia, Vitamin D Deficiency | Phase 1 / Phase 2 | Completed | Zagazig University | 38 | 2019-03-01 | 2021-12-08 |
| Ga-DOTATATE PET for Phosphaturic Mesenchymal Tumors in Patients With Tumor Induced Osteomalacia 68Ga-DOTATATE PET/CT - Osteomalacia | Phase 1 / Phase 2 | Completed | Mayo Clinic | 18 | 2019-01-31 | 2025-04-30 |
| The Effect of Etelcalcetide on CKD-MBD Etelcalcetide - Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy | Phase 2 | Completed | Thomas Nickolas, MD MS | 22 | 2018-09-06 | 2023-09-21 |
| Thiamine as a Renal Protective Agent in Septic Shock Thiamine Hydrochloride, Placebo - Sepsis, Kidney Injury | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 95 | 2018-09-04 | 2023-06-27 |
| Vitamin D and Arterial Stiffness in Elderly Low dose vitamin D3, High dose vitamin D3 - Vitamin D Deficiency, Arterial Stiffness | Phase 2 | Completed | Texas Tech University Health Sciences Center | 52 | 2018-08-16 | 2022-03-21 |
| Cholecalciferol on Hemodialysis Patients Cholecalciferol, Placebo - Hemodialysis Complication, Vitamin D Deficiency | Phase 2 / Phase 3 | Completed | Ain Shams University | 60 | 2018-07-01 | 2019-01-09 |
| Effectiveness of a Micronutrient Supplement to Lower Plasma Homocysteine MDEG2 Pilot Supplementation Trial novel micronutrient, existing micronutrient supplement, UNIMMAP - Micronutrient Deficiencies, Hyperhomocysteinemia | Phase 2 | Completed | London School of Hygiene and Tropical Medicine | 298 | 2018-04-26 | 2019-01-22 |
| Blood Pressure in Blacks and Calcium (BBC) and Vitamin D Study Cholecalciferol - Hypertension, Vitamin D Deficiency | Phase 2 | Completed | Loyola University | 5 | 2018-03-25 | 2020-06-24 |
| 'Palliative-D' Vitamin D to Palliative Cancer Patients Cholecalciferol, Placebo - Vitamin D Deficiency | Phase 2 | Completed | Region Stockholm | 244 | 2017-11-01 | 2020-09-11 |
| High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Thiamine, Normal saline - Hematopoietic Stem Cell Transplantation, Delirium | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 66 | 2017-10-16 | 2021-10-19 |
| The Effects of Oral Vitamin D Supplementation on the Prevention of Peritoneal Dialysis-related Peritonitis Cholecalciferol (2000iu qd), Routine therapy for PD - Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency | Phase 2 | Completed | Peking University First Hospital | 60 | 2017-09-30 | 2021-08-18 |
Showing 20 of 89. Sign in to see all of them.
Vitamin D Deficiency (51) · Osteomalacia (9) · Rickets (9) · Bone Diseases (7) · Chronic Kidney Disease-Mineral and Bone Disorder (7) · Familial Hypophosphatemic Rickets (7) · Hypophosphatasia (6) · Vitamin A Deficiency (6) · Hypertension (4) · Insulin Resistance (4) · Respiratory Tract Infections (4) · Avitaminosis (3) · Diabetes Mellitus (3) · HIV Infections (3) · Kidney Failure, Chronic (3)
Malnutrition (89) · Nutritional and Metabolic Diseases (89) · Nutrition Disorders (88) · Avitaminosis (86) · Metabolic Diseases (36) · Calcium Metabolism Disorders (27) · Musculoskeletal Diseases (25) · Bone Diseases, Metabolic (23) · Urogenital Diseases (23) · Vitamin D Deficiency (22) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (19) · Female Urogenital Diseases and Pregnancy Complications (19) · Bone Diseases (18) · Pathological Conditions, Signs and Symptoms (18)
Cholecalciferol (35) · Vitamin D (13) · burosumab (7) · asfotase alfa (6) · Vitamin A (4) · Calcifediol (3) · Calcitriol (3) · Ascorbic Acid (2) · Calcium Carbonate (2) · Growth Hormone (2) · Saline Solution (2) · Thiamine (2) · etelcalcetide hydrochloride (2) · thiamine hydrochloride (2) · 1 alpha-hydroxyergocalciferol (1)
Alexion Pharmaceuticals, Inc. (6) · Ain Shams University (3) · Kyowa Kirin, Inc. (3) · Children's Hospital of Eastern Ontario (2) · Jewish General Hospital (2) · Kyowa Kirin Co., Ltd. (2) · Mayo Clinic (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Regional Hospital Holstebro (2) · University Hospitals Cleveland Medical Center (2) · University of Aarhus (2) · University of Toronto (2) · Al-Balqa Applied University (1) · Alborz Medical University (1) · Allina Health System (1)
United States (43) · Canada (13) · United Kingdom (6) · Denmark (5) · Egypt (5) · France (4) · Italy (4) · Austria (3) · Spain (3) · Australia (2) · China (2) · Saudi Arabia (2) · Sweden (2) · United Arab Emirates (2) · Bangladesh (1)
Amy Zhang, PhD (2) · Adit A Ginde, MD, MPH (1) · Alison M Boyce, M.D. (1) · Amrein Karin (1) · Andrew Prentice, PhD (1) · Anne-Mette Hvas, MD, Ph.D. (1) · Ari Moskowitz, MD (1) · Ariel A. Salas, MD (1) · Betty J Burri, PhD (1) · Bradley D Berry, MD (1) · Celia Rodd, MD (1) · Chanita Hughes-Halbert, PhD (1) · Cynthia Aranow, MD (1) · Daniel O Young, MD (1)
PMID 26529632, PMID 32417537, PMID 32762706, PMID 33305842, PMID 25919461, PMID 27699270, PMID 32721016, PMID 39151033, PMID 40576086, PMID 10523553, PMID 14608059, PMID 15075545, PMID 15699235, PMID 15795468, PMID 15821396, PMID 18397701, PMID 19244376, PMID 19776051, PMID 19829124, PMID 20130093, PMID 21697075, PMID 21791335, PMID 22293363, PMID 22301548, PMID 22397652, PMID 22412025, PMID 22854406, PMID 22854639, PMID 23632722, PMID 23885048, PMID 24120120, PMID 24290111, PMID 24451309, PMID 24455219, PMID 24661355, PMID 24711745, PMID 25004404, PMID 25527663, PMID 25777546, PMID 25872802, PMID 25955191, PMID 26073451, PMID 26201817, PMID 26353829, PMID 26725194, PMID 26765812, PMID 26890209, PMID 27079965, PMID 27784345, PMID 27861708
K23AG040708 (1), R01DK060021 (1), U54MD010706 (1)