7 completed, 4 not yet recruiting, 4 unknown, 2 withdrawn. 8 Not applicable, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Not yet recruiting 2, Unknown 2, Withdrawn 1 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Cytoreductive Surgery: new trials by email Literature Review of Cytoreductive Surgery trials Research Report on Cytoreductive Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Quality Of Life And Symptom Assessment Among Recurrence-Free Patients Who Underwent Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Questionnaire and Physical Exam - Long Term, Quality of Life | Not yet recruiting | M.D. Anderson Cancer Center | 300 | 2027-03-22 | 2026-10-13 | |
| Impact of an Omega-3 Enriched Oral Nutritional Supplement on Improving Surgical Outcomes in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery ONS enriched with Omega-3, Standard ONS - Peritoneal Carcinosis, Peritoneal Metastases | Not applicable | Not yet recruiting | Catholic University of the Sacred Heart | 28 | 2026-04-01 | 2026-03-17 |
| Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management. Ventral Hernias, Cytoreductive Surgery | Recruiting | Jules Bordet Institute | 500 | 2026-01-20 | 2026-03-05 | |
| HIPEC Surgery and Hemodynamics Hemodynamics, Cytoreductive Surgery | Not yet recruiting | Miray Gözde Özdemir | 15 | 2025-04-01 | 2025-04-13 | |
| Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer esketamine, placebo - Ovarian Cancer, Cytoreductive Surgery | Not applicable | Completed | Zhejiang Cancer Hospital | 568 | 2024-10-08 | 2026-02-27 |
| PET/MRI in Endometrial Cancer PET/MRI with radiotracer ([18F]- fluorodeoxyglucose) and a gadolinium-based contrast agent - Cytoreductive Surgery, Grade 3 Endometrial Endometrioid Adenocarcinoma | Not applicable | Withdrawn | Massachusetts General Hospital | 2024-03-30 | 2024-04-02 | |
| Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC Urine-guided hydration, Routine hydration, Forced administration of furosemide - Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy | Not applicable | Completed | Peking University First Hospital | 168 | 2023-07-24 | 2025-03-19 |
| ECO-LEAK Technique: Early Detection of Colorectal Anastomotic Leakage by Transvaginal Ultrasound ECO-LEAK transvaginal ultrasound, ECO-LEAK with CT-Scan or rectoscopy, CT-Scan or rectoscopy - Gynecologic Cancer, Anastomotic Leak | Unknown | Instituto de Investigacion Sanitaria La Fe | 766 | 2023-04-17 | 2023-07-21 | |
| Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancer cytoreductive surgery - Cytoreductive Surgery | Not applicable | Not yet recruiting | Women's Hospital School Of Medicine Zhejiang University | 140 | 2022-12-01 | 2022-12-01 |
| Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy Arm I (QL block and multimodal analgesia), Arm II (multimodal analgesia without regional block) - Cytoreductive Surgery, Hyperthermic Intra-peritoneal Chemotherapy | Not applicable | Unknown | Gangnam Severance Hospital | 50 | 2022-11-15 | 2024-08-15 |
| Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases Preoperative systematic therapy, CRS+HIPEC, Postoperative chemotherapy - Colorectal Neoplasms, Colorectal Cancer | Phase 2 | Unknown | Sun Yat-sen University | 168 | 2022-06-01 | 2022-04-29 |
| CRS & HIPEC for Platinum-Resistant Recurrent Ovarian Cancer (KOV-02R, RECOVER) HIPEC - Epithelial Ovarian Cancer, Platinum Resistant | Phase 3 | Active not recruiting | National Cancer Center, Korea | 140 | 2022-04-07 | 2026-02-12 |
| Role of Magnetic Resonance Enterography for Predicting Peritoneal Cancer Index MRI - Hyperthermic Intraperitoneal Chemotherapy, Cytoreductive Surgery | Not applicable | Unknown | Chang Gung Memorial Hospital | 90 | 2021-09-01 | 2021-10-18 |
| TAP and IMS for HIPEC IVPCA, TAP, IMS - Cytoreductive Surgery | Phase 3 | Completed | Gangnam Severance Hospital | 81 | 2021-08-21 | 2022-10-10 |
| Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment Peritoneal Metastases, Peritoneal Carcinomatosis | Completed | University of Aarhus | 90 | 2021-04-06 | 2024-05-29 | |
| Anesthesia Management in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy | Completed | Sanliurfa Mehmet Akif Inan Education and Research Hospital | 50 | 2020-01-01 | 2024-05-06 | |
| What Are the Experiences of Patients With Pseudomyxoma Peritonei? Pseudomyxoma Peritonei, Cytoreductive Surgery | Withdrawn | University of Southampton | 2019-11-01 | 2020-01-31 | ||
| Single Dose Tranexamic Acid in Reducing Blood Loss During Cytoreductive Surgery and HIPEC tranexamic Acid infusion, saline infusion - Cytoreductive Surgery | Not applicable | Completed | Assiut University | 46 | 2018-08-30 | 2022-06-07 |
| Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery Serum procalcitonin lab draws - Cytoreductive Surgery | Completed | Eastern Regional Medical Center | 20 | 2014-06-01 | 2017-07-12 |
Peritoneal Neoplasms (4) · Colorectal Neoplasms (3) · Ovarian Neoplasms (2) · Postoperative Complications (2) · Pseudomyxoma Peritonei (2) · Acute Kidney Injury (1) · Anastomotic Leak (1) · Carcinoma, Ovarian Epithelial (1) · Colonic Neoplasms (1) · Depression (1) · Hemorrhage (1) · Hernia, Ventral (1) · Intestinal Neoplasms (1) · Neoplasms (1) · Rectal Neoplasms (1)
Neoplasms (6) · Neoplasms by Site (6) · Abdominal Neoplasms (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Pathological Conditions, Signs and Symptoms (4) · Peritoneal Diseases (4) · Carcinoma (3) · Colonic Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Gastrointestinal Diseases (3) · Gastrointestinal Neoplasms (3) · Intestinal Diseases (3) · Neoplasms by Histologic Type (3)
Cytoreduction Surgical Procedures (1) · Docosahexaenoic Acids (1) · Esketamine (1) · Fluorodeoxyglucose F18 (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Proctoscopy (1) · Restraint, Physical (1) · Surveys and Questionnaires (1) · Tomography, X-Ray Computed (1)
Gangnam Severance Hospital (2) · Assiut University (1) · Catholic University of the Sacred Heart (1) · Chang Gung Memorial Hospital (1) · Eastern Regional Medical Center (1) · Instituto de Investigacion Sanitaria La Fe (1) · Jules Bordet Institute (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1) · Miray Gözde Özdemir (1) · National Cancer Center, Korea (1) · Peking University First Hospital (1) · Sanliurfa Mehmet Akif Inan Education and Research Hospital (1) · Sun Yat-sen University (1) · University of Aarhus (1)
China (4) · South Korea (3) · Turkey (Türkiye) (2) · United States (2) · Belgium (1) · Denmark (1) · Egypt (1) · Italy (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Anne-Mette Hvas, MD, PhD (1) · Chia-Ni Lin, MA (1) · Dong-Xin Wang, MD, PhD (1) · Gabriel Liberale, MD, Phd (1) · Onofrio Catalono, MD, PhD (1) · Rod Flynn, MD (1) · Young Song (1) · Yun Song, MD (1)