6 recruiting. 6 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Recruiting 6 |
| Phase 2 | 3 | Recruiting 3 |
Follow cyclopia sequence: new trials by email Literature Review of cyclopia sequence trials Research Report on cyclopia sequence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis Minocycline Hydrochloride Capsule (50 mg per capsule), Placebo of Minocycline Hydrochloride Capsule (50 mg per capsule, containing 0 mg of minocycline) - Ischaemic Stroke | Phase 3 | Recruiting | Beijing Tiantan Hospital | 934 | 2026-06-05 | 2026-07-01 |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA) Minocycline hydrochloride capsule, Placebo capsules of Minocycline hydrochloride capsules - Acute Ischemic Stroke, Vessel Occlusion | Phase 2 / Phase 3 | Recruiting | Xiang Luo | 860 | 2026-05-21 | 2026-05-27 |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP) Minocycline hydrochloride capsule, Placebo capsules of Minocycline hydrochloride capsules - Acute Ischemic Stroke, Endovascular Thrombectomy | Phase 2 / Phase 3 | Recruiting | Xiang Luo | 234 | 2026-05-19 | 2026-05-22 |
| Efficacy and Safety of Minocycline in Acute Spontaneous Intracerebral Hemorrhage Minocycline hydrochloride capsules, Placebo capsules of Minocycline hydrochloride capsules - Intracerebral Hemorrhage | Phase 3 | Recruiting | Beijing Tiantan Hospital | 1192 | 2026-04-02 | 2026-04-23 |
| Minocycline in Stroke Study at Maimonides Minocycline 200mg - Stroke, Ischemia Stroke | Phase 2 / Phase 3 | Recruiting | Joyce Chen | 1164 | 2026-02-02 | 2026-03-19 |
| INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder Celecoxib, Minocyclin, Placebo - Major Depressive Disorder, Inflammation | Phase 3 | Recruiting | Universiteit Antwerpen | 240 | 2023-09-21 | 2024-10-15 |
Ischemic Stroke (4) · Cerebral Hemorrhage (2) · Arterial Occlusive Diseases (1) · Brain Infarction (1) · Depressive Disorder, Major (1) · Hemorrhagic Stroke (1) · Inflammation (1) · Stroke (1)
Brain Diseases (5) · Cardiovascular Diseases (5) · Central Nervous System Diseases (5) · Cerebrovascular Disorders (5) · Nervous System Diseases (5) · Vascular Diseases (5) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Stroke (3) · Hemorrhage (2) · Intracranial Hemorrhages (2) · Brain Ischemia (1) · Depressive Disorder (1) · Infarction (1) · Ischemia (1)
Minocycline (6) · Celecoxib (1)
Beijing Tiantan Hospital (2) · Xiang Luo (2) · Joyce Chen (1) · Universiteit Antwerpen (1)
China (4) · Belgium (1) · United States (1)
Xiang Luo (2) · Anxin Wang, PhD (1) · Manuel Morrens, MD PhD (1) · Qingliang T. Wang, MD, PhD (1) · Yilong Wang, MD, PhD (1)
PMID 10557349, PMID 11880505, PMID 15760647, PMID 16033424, PMID 17909152, PMID 21169826, PMID 22943144, PMID 23085382, PMID 25003359, PMID 26396030, PMID 28275199, PMID 28887388, PMID 28929560, PMID 30319113, PMID 30938800, PMID 31919518, PMID 33212054, PMID 34487721, PMID 34838196, PMID 35465695, PMID 35579034, PMID 36180765, PMID 36274585, PMID 36300975, PMID 39350954, PMID 40147820