7 completed, 2 unknown, 1 not yet recruiting, 1 terminated. 11 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 7, Unknown 2, Not yet recruiting 1, Terminated 1 |
Follow cyclopia sequence: new trials by email Literature Review of cyclopia sequence trials Research Report on cyclopia sequence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of Minocycline Hydrochloride Injectable Hydrogel for the Treatment of Periodontitis treatment group - Periodontitis | Not applicable | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 80 | 2026-05-01 | 2026-05-28 |
| Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories Imagery, Minocycline, Placebo - Post-traumatic Stress Disorder, Cocaine Use Disorder | Not applicable | Completed | Psychiatric University Hospital, Zurich | 138 | 2023-05-10 | 2026-03-06 |
| Comparison of Efficacy of Minocyclin and Celecoxib as Adjunctive Treatment in Treatment Resistant Cases of Major Depressive Disorder Minocycline, Celecoxib - Major Depressive Disorder (MDD), Treatment-resistant Depression (TRD) | Not applicable | Completed | Lahore General Hospital | 78 | 2022-05-12 | 2026-09-04 |
| Minocycline in the Treatment of Angelman Syndrome minocycline - Angelman Syndrome | Not applicable | Completed | University of South Florida | 25 | 2012-04-01 | 2023-04-18 |
| Minocycline Augmentation in Schizophrenia Minocycline, Placebo - Schizophrenia | Not applicable | Unknown | The University of Texas Health Science Center, Houston | 120 | 2012-02-01 | 2012-03-23 |
| Effects of Minocycline on Cytokine Levels in Severe Meibomian Gland Dysfunction oral minocycline hydrochloride treatment - Meibomian Gland Dysfunction | Not applicable | Completed | Yonsei University | 46 | 2011-11-01 | 2014-03-05 |
| A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil Armodafinil, Placebo, Minocycline - Lung Cancer | Not applicable | Completed | M.D. Anderson Cancer Center | 14 | 2011-07-01 | 2020-02-10 |
| Trial of Minocycline to Treat Children With Fragile X Syndrome minocycline hydrochloride, Placebo - Fragile X Syndrome | Not applicable | Completed | University of California, Davis | 66 | 2010-01-01 | 2017-05-30 |
| Enoxaparin and/or Minocycline in Acute Stroke Enoxaparin, Minocycline - Acute Ischemic Stroke | Not applicable | Terminated | NYU Langone Health | 6 | 2009-04-01 | 2016-04-29 |
| Minocycline and Proteinuria in Diabetic Nephropathy Minocycline 100 mg po bid for 6 months, placebo - Diabetic Nephropathy | Not applicable | Unknown | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 30 | 2009-02-01 | 2015-05-21 |
| Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery minocycline, placebo - Kidney Failure, Acute, Acute Kidney Insufficiency | Not applicable | Completed | Tarek M. El-Achkar | 40 | 2007-12-01 | 2017-12-22 |
Acute Kidney Injury (1) · Albuminuria (1) · Angelman Syndrome (1) · Anorexia (1) · Carcinoma, Non-Small-Cell Lung (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Diabetic Nephropathies (1) · Fatigue (1) · Fragile X Syndrome (1) · Ischemic Stroke (1) · Lung Neoplasms (1) · Meibomian Gland Dysfunction (1) · Pain (1)
Mental Disorders (4) · Nervous System Diseases (4) · Central Nervous System Diseases (2) · Chromosome Disorders (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genetic Diseases, Inborn (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Urogenital Diseases (2)
Minocycline (9) · Celecoxib (1) · Enoxaparin (1) · Modafinil (1) · Sugars (1) · Surveys and Questionnaires (1) · Tetracycline (1)
Lahore General Hospital (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · M.D. Anderson Cancer Center (1) · NYU Langone Health (1) · Psychiatric University Hospital, Zurich (1) · Tarek M. El-Achkar (1) · The First Affiliated Hospital of Xinxiang Medical College (1) · The University of Texas Health Science Center, Houston (1) · University of California, Davis (1) · University of South Florida (1) · Yonsei University (1)
United States (7) · Pakistan (1) · South Korea (1) · Switzerland (1)
Birgit Kleim, Prof. Dr. (1) · Boris B. Quednow, Prof. Dr. (1) · Edwin J Weeber, Ph.D. (1) · Farhana Ashraf (1) · Giacinto Grieco, M.D. (1) · Mujeeb U Shad, MD, MSCS (1) · Randi J Hagerman, MD (1) · Saran Jonas, M.D. (1) · Sharon G Adler, MD (1) · Tarek M El-Achkar, MD (1) · Wenjie Ren (1) · Zhongxing Liao, MD (1)
PMID 21450915, PMID 21450917, PMID 21450918, PMID 2234831, PMID 22967863, PMID 25348221, PMID 25491305, PMID 27019421