98 completed, 55 unknown, 27 recruiting, 15 not yet recruiting. 225 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 225 | Completed 98, Unknown 55, Recruiting 27, Not yet recruiting 15, Terminated 11, Enrolling by invitation 8, Withdrawn 7, Active not recruiting 4 |
Follow Craniofacial Abnormalities: new trials by email Literature Review of Craniofacial Abnormalities trials Research Report on Craniofacial Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Tummy Time Associated With Therapeutic Positioning in Premature Newborns With Cranial Asymmetry Tummy Time Protocol - Premature Newborns, Cranial Asymmetry | Not applicable | Not yet recruiting | Hospital de Clinicas de Porto Alegre | 300 | 2026-10-01 | 2026-09-18 |
| Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates - Malocclusion, Angle Class II, Malocclusion, Angle Class III | Not applicable | Recruiting | Future University in Egypt | 12 | 2026-10-01 | 2026-09-25 |
| Frontal Reconstruction Without Orbital Advancement for Moderate Metopic Craniosynostosis Frontal vault remodelling without orbital advancement - Metopic Craniosynostosis, Craniosynostosis | Not applicable | Not yet recruiting | Assiut University | 15 | 2026-10-01 | 2026-09-23 |
| Furlow With Buccinator and Fistula Formation furlow with buccinator, two flap palatoplasty - Cleft Palate | Not applicable | Not yet recruiting | Fayoum University | 20 | 2026-09-25 | 2026-09-25 |
| Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion Low Sagittal Medial Ramus Osteotomy - Skeletal Class II Malocclusion, Skeletal Class III Malocclusion | Not applicable | Not yet recruiting | Al-Azhar University | 11 | 2026-09-01 | 2026-08-05 |
| Treatment for "Asymmetric Crying Facies" Botulinium toxin type A injection - Hemifacial Microsomia, Facial Nerve Paralysis | Not applicable | Recruiting | Xiaolei Jin | 60 | 2026-08-07 | 2026-09-28 |
| Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF - Cleft Palate, Unilateral Cleft Palate | Not applicable | Recruiting | Al-Thawra Modern General Hospital | 90 | 2026-08-01 | 2026-08-07 |
| Speech Intervention Frameworks in Cantonese-speaking Children and Adolescences With Cleft Palate +/- Lip Non-linear based phonological speech intervention, Linear-based speech intervention - Cleft Palate +/- Lip | Not applicable | Enrolling by invitation | Chinese University of Hong Kong | 12 | 2026-07-24 | 2026-07-09 |
| MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair Modified Furlow Palatoplasty combined with buccinator myomucosal flap - Cleft Palate, Cleft Palate, Unilateral, Complete | Not applicable | Not yet recruiting | Cairo University | 10 | 2026-06-01 | 2026-04-07 |
| Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery Bone Ring Technique (BRT) - Maxillary Deficiency, Bone Resorption | Not applicable | Recruiting | Damascus University | 10 | 2026-05-31 | 2026-09-01 |
| Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction. Patient-specific titanium implants for facial reconstruction - Hemifacial Microsomia, Mucormycosis | Not applicable | Recruiting | Latakia University | 30 | 2026-04-26 | 2026-06-17 |
| Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients Observational Assessment - Orthognathic Surgery, Malocclusions | Not applicable | Enrolling by invitation | Lithuanian University of Health Sciences | 100 | 2026-03-03 | 2026-03-17 |
| Speech Intervention Via Telepractice for Children With Repaired Cleft Palate Speech therapy via teleprace, Face-to-face speech therapy - Cleft Palate Children, Speech Sound Disorder | Not applicable | Not yet recruiting | Texas Tech University Health Sciences Center | 64 | 2026-03-02 | 2026-02-27 |
| Effects of AlignBabyCleft (ABaCleft) Appliance. Orthodontic appliance to carry out dentoalveolar movement - Cleft Lip, Cleft Palate | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 30 | 2025-11-21 | 2025-04-25 |
| Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. Early intervention for language, articulation and palatal function skills - Cleft Lip and Cleft Palate, Cleft Lip Palate | Not applicable | Not yet recruiting | Old Dominion University | 200 | 2025-10-21 | 2025-10-22 |
| Palliative Care Needs of Children With Rare Diseases and Their Families Family Centered pediatric palliative care for family caregivers of children with rare diseases. - Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia | Not applicable | Enrolling by invitation | Children's National Research Institute | 480 | 2025-10-02 | 2026-01-28 |
| Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite. The Leaf expander, Hyrax expander - Posterior Crossbite, Maxilla; Hypoplasia | Not applicable | Recruiting | Cairo University | 30 | 2025-10-01 | 2026-06-04 |
| Trial to Compare the Effects of Myo Munchee Therapy and Oral Motor Therapy (OMT) in Pediatric Patients to Treat Maxillary Deficiency and Orofacial Myofunctional Dysfunction (OMD). Chewing device only, Myo Munchee and Oral Motor Therapy Treatment, Oral Motor Therapy Treatment Arm - Orofacial Myofunctional Disorders, Myo Munchee | Not applicable | Recruiting | Myo Munchee (Operations) Pty Ltd | 48 | 2025-08-20 | 2025-07-28 |
| Predictors of Patient-Reported Outcomes for Maxillectomy Patients Digitally Fabricated Obturator Prosthesis - Maxillary Deficiency, Head and Neck Neoplasms | Not applicable | Completed | Dr. Merve Benli | 75 | 2025-08-12 | 2026-10-08 |
| Effects of Local Ketamine in Orthognathic Procedures Ketamine, Articaine Hydrochloride + Epinephrine - Dentofacial Deformities, Analgesia | Not applicable | Active not recruiting | Bezmialem Vakif University | 40 | 2025-06-21 | 2026-03-27 |
Showing 20 of 225. Sign in to see all of them.
Cleft Palate (53) · Retrognathia (41) · Dentofacial Deformities (22) · Micrognathism (20) · Cleft Lip (19) · Craniosynostoses (18) · DiGeorge Syndrome (12) · Malocclusion, Angle Class III (11) · Maxillofacial Abnormalities (11) · Plagiocephaly, Nonsynostotic (11) · Malocclusion (9) · Plagiocephaly (9) · Pierre Robin Syndrome (8) · Jaw Abnormalities (7)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (225) · Musculoskeletal Abnormalities (224) · Musculoskeletal Diseases (224) · Congenital Abnormalities (220) · Stomatognathic Diseases (152) · Stomatognathic System Abnormalities (150) · Maxillofacial Abnormalities (138) · Jaw Diseases (122) · Jaw Abnormalities (114) · Mouth Diseases (60) · Mouth Abnormalities (55) · Mandibular Diseases (45) · Bone Diseases (37) · Pathological Conditions, Signs and Symptoms (34)
Orthognathic Surgery (3) · Activator Appliances (2) · Biopsy (2) · Enteral Nutrition (2) · Head Protective Devices (2) · Manipulation, Osteopathic (2) · Manual Lymphatic Drainage (2) · Masks (2) · Neuropsychological Tests (2) · Saline Solution (2) · Surveys and Questionnaires (2) · Acetaminophen (1) · Anastrozole (1) · Anesthetics, Local (1) · Betaine (1)
Cairo University (17) · Al-Azhar University (7) · Fayoum University (5) · Alexandria University (4) · Assistance Publique - Hôpitaux de Paris (4) · Assiut University (4) · Damascus University (4) · Hôpital le Vinatier (4) · Bezmialem Vakif University (3) · Centre Hospitalier Universitaire, Amiens (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Hospices Civils de Lyon (3) · Mansoura University (3) · Oslo University Hospital (3) · TC Erciyes University (3)
Egypt (44) · United States (43) · France (21) · Turkey (Türkiye) (15) · Brazil (11) · Canada (8) · Italy (7) · Belgium (5) · Spain (5) · Syria (5) · Hong Kong (4) · Norway (4) · Switzerland (4) · China (3) · Denmark (3)
Chiara Leoni, MD, PhD (3) · Fabianne MG Furtado, PhD (2) · Gabriela PR Prado, MS (2) · Lydia M Ferreira, PhD (2) · Michele DeGrazia, PhD, NNP (2) · Nieto Luis, Master (2) · Orosia Lucha (2) · Stephan Eliez, Professor (2) · Abdulmalek Majanni, DDS MSc (1) · Ahamd Burhan, DDS MSc PhD (1) · Ahmad S. Zakaria, DDS MSc (1) · Ahmed El Shanawany, M.D., Ph.D. (1) · Alessandro Ugolini (1)
PMID 10371309, PMID 10883694, PMID 14707617, PMID 1472517, PMID 16122596, PMID 16448254, PMID 16563165, PMID 18452361, PMID 18980518, PMID 19761925, PMID 21823827, PMID 22002941, PMID 22204448, PMID 22776627, PMID 23690355, PMID 23711443, PMID 24207068, PMID 24951081, PMID 25023781, PMID 25595400, PMID 25823758, PMID 26044111, PMID 26468849, PMID 26847514, PMID 27129491, PMID 27383684, PMID 27624627, PMID 27629273, PMID 28018773, PMID 28279603, PMID 28921849, PMID 29496055, PMID 31002789, PMID 31230767, PMID 31300507, PMID 31614700, PMID 31640736, PMID 31795731, PMID 31827528, PMID 31892114, PMID 31892445, PMID 32049908, PMID 32081579, PMID 32197886, PMID 32249045, PMID 32572853, PMID 33107321, PMID 33397459, PMID 33632268, PMID 33827851
R21DC017553 (2), 2014 (1), 2016 (1), K12HD043494 (1), R01AG076678 (1), R01AI047040 (1), R01DC011524 (1), R01HD117137 (1), R33MH085901 (1), R34MH091314 (1), R42HD081712 (1), U01DE018837 (1), U01HD040561 (1), U01HG006487 (1)