14 completed, 2 not yet recruiting, 1 active not recruiting, 1 recruiting. 15 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 10, Not yet recruiting 2, Active not recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Couples: new trials by email Literature Review of Couples trials Research Report on Couples
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples Online, couples-based intervention - Alcohol Drinking, Cannabis Use | Not applicable | Not yet recruiting | University of Washington | 60 | 2026-10-01 | 2026-07-08 |
| Couple-Coordinated Lifestyle Intervention for Women With a History of Gestational Diabetes Mellitus Couple-based Collaborative Lifestyle Intervention, Woman-only Lifestyle Intervention - Diabetes Prevention, GDM | Not applicable | Not yet recruiting | The Third Xiangya Hospital of Central South University | 362 | 2026-08-15 | 2026-08-13 |
| Zithandani Stepping Stones and Creating Futures - Phase 2 Pilot Zithandani Stepping Stones and Creating Futures - Intimate Partner Violence (IPV), Earning Outcomes | Not applicable | Completed | University of Exeter | 104 | 2025-07-08 | 2026-06-11 |
| A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers Young Adults Coping with Cancer Together Intervention - Cancer, Survivorship | Not applicable | Completed | Massachusetts General Hospital | 20 | 2024-04-19 | 2026-10-05 |
| Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship Alcohol Administration - Alcohol Use Disorder, Posttraumatic Stress Disorder | Not applicable | Recruiting | Medical University of South Carolina | 140 | 2024-03-01 | 2026-04-03 |
| TYRO Couples Project Study Intervention #1: Treatment Group Receiving On-Demand TYRO Services, Intervention #2: Control Group Receiving In-Person TYRO Services - Couples | Not applicable | Completed | Midwest Evaluation & Research | 820 | 2023-04-11 | 2025-09-19 |
| Wearable Technology and Alcohol-Facilitated Intimate Partner Violence Heart Rate Variability-Biofeedback (HRV-B) via Smartwatch Device Intervention - Alcohol Abuse, IPV | Not applicable | Completed | Medical University of South Carolina | 92 | 2023-01-27 | 2025-07-14 |
| Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD) ReStoreD - Stroke, Depression, Anxiety | Not applicable | Active not recruiting | University of Utah | 400 | 2022-07-20 | 2026-01-30 |
| The Effects of Relational Letter Writing Relational Letter Writing - Relational Problems, Couples | Not applicable | Unknown | Universitat Oberta de Catalunya | 68 | 2022-06-15 | 2022-05-18 |
| Empowering Families Project Family Wellness, Career Coaching, Financial Planning - Couples, Relationship, Marital | Not applicable | Completed | University of Texas at Austin | 666 | 2022-05-01 | 2026-02-10 |
| Effectiveness and Satisfaction With the Gottman Couple Enhancement Course Participation in the couple enhancement program - Couples | Completed | Rune Zahl-Olsen | 732 | 2021-03-01 | 2022-11-01 | |
| Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder PartnerCHESS, A-CHESS - Alcohol Use Disorder, Couples | Not applicable | Completed | University of Wisconsin, Madison | 68 | 2020-11-17 | 2025-04-22 |
| Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT) Oxytocin, Placebo - Alcohol Use Disorder, Couples | Phase 2 | Completed | Medical University of South Carolina | 192 | 2019-05-16 | 2025-02-21 |
| Cancer Survivors and Their Romantic Partners' Preferences for a Couples-based Physical Activity Cancer-Specific Exercise education - Cancer Diagnosis, Couples | Completed | University of Colorado, Denver | 448 | 2018-06-14 | 2024-05-10 | |
| Promoting Female Empowerment at the Household Level Among Couples in Ibadan, Nigeria Gender Socialization Training workshop, Financial Literacy Training Intervention, Family Planning Counseling and Services - Gender Role, Woman's Role | Not applicable | Completed | University of Ibadan | 2472 | 2017-09-15 | 2020-03-31 |
| Couple Interaction and Health Behaviors Cognitive Intervention, Behavioral Intervention, Interpretation Bias - Couples, Relationship, Marital | Not applicable | Completed | NYU Langone Health | 142 | 2017-05-01 | 2020-11-13 |
| Project Nexus: Providing Online Counseling for Home-Based HIV Testing Couples HIV Testing and Counseling (CHTC, CVCT), at-home test kit - Couples | Not applicable | Completed | University of Michigan | 800 | 2016-04-01 | 2019-10-21 |
| Vitamin D Deficiency of Couples and Infertility vitamin D is below 20ng/ml - Vitamin D Deficiency, Infertility | Completed | Tongji Hospital | 1500 | 2016-03-01 | 2017-10-10 | |
| Days in Motion: A Planning Intervention Study With Couples to Enhance Daily Physical Activity Dyadic planning intervention, Individual planning intervention, General motivational treatment - Health Behavior, Physical Activity | Not applicable | Completed | Freie Universität Berlin | 346 | 2013-03-01 | 2016-01-06 |
Alcoholism (4) · Alcohol Drinking (1) · Anxiety Disorders (1) · Behavior, Addictive (1) · Caregiver Burden (1) · Depression (1) · Health Behavior (1) · Infertility (1) · Literacy (1) · Motor Activity (1) · Neoplasms (1) · Psychological Well-Being (1) · Stress Disorders, Post-Traumatic (1) · Stroke (1) · Vitamin D Deficiency (1)
Behavior (7) · Mental Disorders (5) · Alcohol-Related Disorders (4) · Chemically-Induced Disorders (4) · Substance-Related Disorders (4) · Behavioral Symptoms (2) · Avitaminosis (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Communication (1) · Compulsive Behavior (1) · Deficiency Diseases (1) · Drinking Behavior (1)
Behavior Therapy (1) · Counseling (1) · Ethanol (1) · Family Planning Services (1) · Oxytocin (1) · Sodium Chloride (1) · chitinase C (1)
Medical University of South Carolina (3) · Freie Universität Berlin (1) · Massachusetts General Hospital (1) · Midwest Evaluation & Research (1) · NYU Langone Health (1) · Rune Zahl-Olsen (1) · The Third Xiangya Hospital of Central South University (1) · Tongji Hospital (1) · Universitat Oberta de Catalunya (1) · University of Colorado, Denver (1) · University of Exeter (1) · University of Ibadan (1) · University of Michigan (1) · University of Texas at Austin (1) · University of Utah (1)
United States (11) · China (1) · Germany (1) · Nigeria (1) · Norway (1) · South Africa (1)
Adrian Montesano (1) · Alexandra L Terrill, PhD (1) · Chunxia Cheng (1) · David H Gustafson, PhD (1) · Funmilola OlaOlorun, PhD (1) · Giselle K Perez, Ph.D. (1) · Jamie M Jacobs, Ph.D. (1) · Julianne Flanagan, PhD (1) · Kun Qian, Doctor (1) · Matt D Shepherd, PhD (1) · Nina Knoll, Univ.-Prof. (1) · Richard Heyman (1) · Rob Stephenson, PhD (1) · Rune Zahl-Olsen (1)
PMID 18292404, PMID 27642760, PMID 28559225, PMID 32503520, PMID 35140139, PMID 37330256, PMID 39486022
1UH2DE025980-01 (1), K23AA031034 (1), R01AA027212 (1), R21AA029235 (1), R34AA025675 (1)