4 completed, 2 recruiting, 1 not yet recruiting. 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Corticobasal Syndrome (CBS): new trials by email Literature Review of Corticobasal Syndrome (CBS) trials Research Report on Corticobasal Syndrome (CBS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia Spectrum Frontotemporal Lobar Degeneration (FTLD), Frontotemporal Dementia (FTD) | Not yet recruiting | BioSensics | 60 | 2026-11-01 | 2026-10-13 | |
| Imaging Studies in Corticobasal Syndrome C-11 ER176 Radiotracer, C-11 PiB, AV1451 Tau - Cortico Basal Degeneration, Corticobasal Syndrome | Recruiting | Jennifer Whitwell | 80 | 2025-06-25 | 2026-07-14 | |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS) RAVICTI 1.1 g/ml, Placebo - Corticobasal Syndrome (CBS) | Phase 2 | Completed | Technical University of Munich | 32 | 2023-12-12 | 2026-09-11 |
| 4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2 Observational Study - Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS) | Completed | University of California, San Francisco | 293 | 2016-01-01 | 2025-04-13 | |
| Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) FTLD, Progressive Supranuclear Palsy (PSP) | Completed | University of California, San Francisco | 1489 | 2014-09-01 | 2021-05-21 | |
| Safety Study of TPI-287 to Treat CBS and PSP TPI 287 2 mg/m2, TPI-287 20 mg/m2, Placebo - Primary Four Repeat Tauopathies (4RT), Corticobasal Syndrome (CBS) | Phase 1 | Completed | University of California, San Francisco | 44 | 2014-05-01 | 2020-04-15 |
Corticobasal Degeneration (7) · Supranuclear Palsy, Progressive (4) · Color Vision Defects (3) · Frontotemporal Dementia (2) · Frontotemporal Lobar Degeneration (2) · Amyotrophic Lateral Sclerosis (1) · Multiple System Atrophy (1) · Multiple system atrophy (MSA) with orthostatic hypotension (1) · Nerve Degeneration (1) · Neurodegenerative Diseases (1) · Pick Disease of the Brain (1) · Primary Progressive Nonfluent Aphasia (1) · Shy-Drager Syndrome (1)
Nervous System Diseases (7) · Tauopathies (7) · Neurodegenerative Diseases (6) · Brain Diseases (5) · Central Nervous System Diseases (5) · Eye Diseases (5) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Basal Ganglia Diseases (4) · Cranial Nerve Diseases (4) · Movement Disorders (4) · Ocular Motility Disorders (4) · Ophthalmoplegia (4) · Paralysis (4)
Observation (1) · TPI-287 (1) · glycerol phenylbutyrate (1)
University of California, San Francisco (3) · BioSensics (1) · Jennifer Whitwell (1) · Massachusetts General Hospital (1) · Technical University of Munich (1)
United States (6) · Canada (2) · Germany (1)
Adam L Boxer, MD, PhD (2) · Adam Boxer, MD, PhD (1) · Jennifer Whitwell, Ph.D. (1)
PMID 31710340, PMID 33827960, PMID 35492244, PMID 35790423, PMID 38578117, PMID 38959435, PMID 42400090
R01AG038791 (1), R01AG087140 (1), U54NS092089 (1)