7 completed, 3 recruiting, 2 not yet recruiting, 1 active not recruiting. 6 Not applicable, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Recruiting 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 4 | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow Coronary Calcification: new trials by email Literature Review of Coronary Calcification trials Research Report on Coronary Calcification
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AERO CAD Study Evaluating the Shockwave C2 Aero IVL System in Coronary Artery Disease Shockwave C2 Aero Coronary IVL System - Coronary Artery Disease (CAD), Coronary Calcification | Not applicable | Not yet recruiting | OPCI Core Laboratories LLC | 200 | 2026-04-01 | 2026-04-06 |
| DCB vs DES for Severe Coronary Calcification After Optimal Modification Assessed by QFR rotational atherectomy (RA), excimer laser coronary angioplasty (ELCA), Intravascular Lithotripsy (IVL) - Coronary Calcification | Not applicable | Recruiting | Shanghai Zhongshan Hospital | 656 | 2026-02-01 | 2026-03-02 |
| Intravascular Imaging Evaluated Calcified Nodule China Registry Coronary Artery Disease, Coronary Artery Atherosclerosis | Not yet recruiting | Shanghai Zhongshan Hospital | 500 | 2025-12-01 | 2025-12-03 | |
| CAlcified Coronary Lesions Identification & Quantification With X Rays Imaging by IVUS and 3D Stent - Coronary Calcification | Not applicable | Completed | RCF@ICPS | 30 | 2025-11-14 | 2026-06-12 |
| Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment Intravascular lithotripsy, Rotational atherectomy - Coronary Artery Disease, Coronary Calcification | Not applicable | Active not recruiting | Annapoorna Kini | 120 | 2025-10-06 | 2026-10-08 |
| Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK). Orbital atherectomy, Intravascular lithotripsy, Optical Coherence Tomography (OCT) - Coronary Arterial Disease (CAD), Coronary Calcification | Not applicable | Recruiting | Spanish Society of Cardiology | 50 | 2025-06-12 | 2026-04-30 |
| Implementation of a Standardized Algorithm for Coronary Calcification With Plaque Modification Calcium modification - Myocardial Ischaemia, Severely Calcified Coronary Stenoses | Recruiting | Royal College of Surgeons, Ireland | 500 | 2024-09-24 | 2024-11-07 | |
| Safety and Efficacy Evaluation of Orbital Atherectomy System in de Novo Calcified Lesions Diamondback 360TM orbital atherectomy system - Angiography, Coronary Calcification | Unknown | Centre Recherche Cardio Vasculaire Alpes | 300 | 2022-06-15 | 2023-12-20 | |
| IVL and RA in Treatment of Balloon-crossable Severely Calcified Coronary Lesions Rotational atherectomy, Intravascular lithotripsy - Coronary Calcification | Completed | Assiut University | 101 | 2021-05-01 | 2022-08-02 | |
| Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients phytomenadione, placebo solution - Coronary Calcification | Not applicable | Completed | Instituto Mexicano del Seguro Social | 60 | 2017-09-07 | 2020-01-29 |
| Vitamin D and Coronary Calcification Study Calcitriol (Rocaltrol®), Paricalcitol - Chronic Kidney Disease, Vitamin D Deficiency | Phase 4 | Completed | Joslin Diabetes Center | 44 | 2008-09-01 | 2017-12-08 |
| Intravenous Sodium Thiosulfate on Coronary Calcification in Patients on Hemodialysis 25% intravenous (IV) sodium thiosulfate - Coronary Calcification, Vascular Calcification | Phase 2 | Completed | Ramathibodi Hospital | 50 | 2008-07-01 | 2009-12-17 |
| Comparison of Phenprocoumon and Acetylsalicylic Acid (ASA) Valvular Calcification, Coronary Calcification | Completed | RWTH Aachen University | 157 | 2008-02-01 | 2015-09-23 | |
| Vitamin D and Carboxy PTH Fragments in Coronary Calcification Doxercalciferol administration, Doxercalciferol administered by 1-84-7-84 - Coronary Calcification, Endstage Renal Disease | Phase 4 | Withdrawn | Southeast Renal Research Institute | 2008-02-01 | 2020-12-23 | |
| Warfarin and Coronary Calcification Project Coronary Calcification | Completed | Walter Reed Army Medical Center | 70 | 2004-05-01 | 2012-08-24 |
Coronary Artery Disease (4) · Renal Insufficiency, Chronic (2) · Acute Coronary Syndrome (1) · Vascular Calcification (1) · Vitamin D Deficiency (1)
Cardiovascular Diseases (5) · Heart Diseases (5) · Myocardial Ischemia (5) · Vascular Diseases (5) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Coronary Disease (4) · Chronic Disease (2) · Disease Attributes (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Nutritional and Metabolic Diseases (2) · Pathologic Processes (2)
Atherectomy, Coronary (3) · Calcitriol (1) · Injections (1) · Percutaneous Coronary Intervention (1) · Solutions (1) · Tomography, Optical Coherence (1) · Vitamin K (1) · Vitamin K 1 (1) · paricalcitol (1) · sodium thiosulfate (1)
Shanghai Zhongshan Hospital (2) · Annapoorna Kini (1) · Assiut University (1) · Centre Recherche Cardio Vasculaire Alpes (1) · Instituto Mexicano del Seguro Social (1) · Joslin Diabetes Center (1) · OPCI Core Laboratories LLC (1) · RCF@ICPS (1) · RWTH Aachen University (1) · Ramathibodi Hospital (1) · Royal College of Surgeons, Ireland (1) · Southeast Renal Research Institute (1) · Spanish Society of Cardiology (1) · Walter Reed Army Medical Center (1)
United States (5) · France (2) · China (1) · Germany (1) · Ireland (1) · Mexico (1) · Netherlands (1) · Spain (1) · Thailand (1)
Allen Jeremias, MD, MSc (1) · Annapoorna S Kini, MD (1) · Hilda E Macias Cervantes, Doctor (1) · Iannis Karalis, Doctor (1) · James A. Tumlin, MD (1) · Johan W Jukema, professor (1) · Marco A Ocampo Apolonio, Doctor (1) · Mohamed AA Mousa, Doctor (1) · Mohamed Abdelghany, professor (1) · Robert A Byrne (1) · Rodolfo Guardado Mendonza, Doctor (1) · Salma M Taha, Lecturer (1)
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