2 completed, 1 not yet recruiting, 1 recruiting, 1 withdrawn. 5 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Cooling: new trials by email Literature Review of Cooling trials Research Report on Cooling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Vigorous Versus Low Intensity Cool Room Treadmill Training in People with Multiple Sclerosis Body-weight supported treadmill training in a room cooled to 16°C - Multiple Sclerosis, Neurological Rehabilitation | Not applicable | Withdrawn | Memorial University of Newfoundland | 2030-01-01 | 2024-11-27 | |
| Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b) Non-invasive convective head cooling, Standard of Care (SOC) - Stroke, Acute Ischemic Stroke | Not applicable | Not yet recruiting | Auckland City Hospital | 182 | 2026-04-10 | 2026-04-13 |
| Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss Cold pack-delivered mild therapeutic hypothermia - Noise Exposure, Noise-induced Hearing Loss | Not applicable | Recruiting | Restorear Devices LLC | 116 | 2024-12-19 | 2026-07-23 |
| Efficacy of Ceiling Fans for Mitigating Thermal Strain During Bed Rest in Older Adults During Heat Waves No cooling (control), Cooling with ceiling fan - Hyperthermia, Heat Stress | Not applicable | Completed | University of Ottawa | 20 | 2023-12-05 | 2025-02-20 |
| Temperature Sensitive Release of PGE2 and Diminished Energy Requirements in Synovial Tissue With Postoperative Cryotherapy - A Prospective Randomised Study After Knee Arthroscopy Cooling and compression - Knee Arthroscopy, Meniscus | Not applicable | Completed | Karolinska Institutet | 40 | 2008-01-01 | 2010-11-24 |
Brain Ischemia (1) · Edema (1) · Hearing Loss (1) · Hearing Loss, Hidden (1) · Hearing Loss, Noise-Induced (1) · Heat Stress Disorders (1) · Hyperthermia (1) · Inflammation (1) · Ischemic Stroke (1) · Motor Activity (1) · Multiple Sclerosis (1) · Reperfusion Injury (1) · Stroke (1)
Pathological Conditions, Signs and Symptoms (4) · Nervous System Diseases (3) · Signs and Symptoms (3) · Pathologic Processes (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Behavior (1) · Body Temperature Changes (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1) · Ear Diseases (1)
Standard of Care (1)
Auckland City Hospital (1) · Karolinska Institutet (1) · Memorial University of Newfoundland (1) · Restorear Devices LLC (1) · University of Ottawa (1)
Canada (2) · New Zealand (1) · Sweden (1) · United States (1)
Alan Barber, PhD (1) · Doug Campbell, MBChB (1) · Glen P Kenny, PhD (1) · Michelle Ploughman, PhD (1) · Suhrud M Rajguru, PhD (1) · William Diprose, MBChB (1)
R44DC018760 (1)