17 completed, 4 withdrawn, 1 active not recruiting, 1 not yet recruiting. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 17, Withdrawn 4, Active not recruiting 1, Not yet recruiting 1 |
Follow Conjunctivitis, Bacterial: new trials by email Literature Review of Conjunctivitis, Bacterial trials Research Report on Conjunctivitis, Bacterial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-10-05 | 2026-10-30 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Azithromycin Reduction to Reach Elimination of Trachoma B Azithromycin - Trachoma | Phase 4 | Withdrawn | University of California, San Francisco | 2024-10-01 | 2026-03-13 | |
| Enhancing the A in SAFE for Trachoma Azithromycin for Routine Community-wide MDA, Two Additional Rounds of Azithromycin for Children, Azithromycin for Second Community-wide MDA - Trachoma | Phase 4 | Completed | Emory University | 34630 | 2022-05-04 | 2024-02-29 |
| Kebele Elimination of Trachoma for Ocular Health Azithromycin - Trachoma | Phase 4 | Active not recruiting | University of California, San Francisco | 320000 | 2022-02-07 | 2025-10-23 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Azithromycin Reduction to Reach Elimination of Trachoma Azithromycin - Trachoma | Phase 4 | Completed | University of California, San Francisco | 3931 | 2021-05-29 | 2026-03-25 |
| Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso Azithromycin, Amoxicillin, Cotrimoxazole - Child Development | Phase 4 | Completed | University of California, San Francisco | 252 | 2017-07-04 | 2023-03-02 |
| Mortality Reduction After Oral Azithromycin: Morbidity Study Azithromycin, Placebo - Childhood Mortality | Phase 4 | Completed | University of California, San Francisco | 72000 | 2014-11-01 | 2021-03-17 |
| Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis azithromycin, ivermectin, albendazole - Trachoma, Lymphatic Filariasis | Phase 4 | Withdrawn | Emory University | 2014-02-01 | 2014-05-22 | |
| Tripartite International Research for the Elimination of Trachoma mass treatment with oral azithromycin - Trachoma, Chlamydia | Phase 4 | Completed | University of California, San Francisco | 29000 | 2010-11-01 | 2017-10-11 |
| Study of the Progression of Bacterial Conjunctivitis Symptoms Upon Antibiotic Treatment Vigamox Ophthalmic Solution, BSS placebo - Bacterial Conjunctivitis | Phase 4 | Completed | Alcon Research | 24 | 2008-10-01 | 2010-03-31 |
| Partnership for Rapid Elimination of Trachoma Azithromycin - Trachoma | Phase 4 | Completed | Johns Hopkins University | 128 | 2008-05-01 | 2017-07-18 |
| A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery Trichiasis surgery with absorbable sutures, Trichiasis surgery with non-absorbable sutures - Trachomatous Trichiasis, Trachoma | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 1300 | 2008-03-01 | 2012-01-12 |
| Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger Azithromcyin, Azithromycin - Trachoma, Chlamydia Trachomatis | Phase 4 | Completed | University of California, San Francisco | 1139 | 2008-01-01 | 2012-05-08 |
| A Study to Evaluate the Safety and Efficacy of Gatifloxacin for the Treatment of Bacterial Conjunctivitis gatifloxacin, moxifloxacin 0.5% eye drops - Bacterial Conjunctivitis | Phase 4 | Completed | Allergan | 171 | 2007-06-01 | 2011-09-21 |
| Trachoma Amelioration in Northern Amhara (TANA) Mass treatment with oral azithromycin to an entire community - Trachoma, Chlamydia | Phase 4 | Completed | University of California, San Francisco | 33000 | 2006-06-01 | 2015-09-09 |
| Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora VIGAMOX - Bacterial Conjunctivitis | Phase 4 | Completed | Alcon Research | 137 | 2006-06-01 | 2012-11-02 |
| Impact of Water and Health Education Programs on Trachoma and Ocular C. Trachomatis in Niger water and health education program to improve hygiene - Trachoma | Phase 4 | Completed | Johns Hopkins University | 720 | 2005-12-01 | 2011-10-28 |
| Azithromycin in Control of Trachoma II Azithromycin - Trachoma | Phase 4 | Withdrawn | University of California, San Francisco | 2005-06-01 | 2012-04-16 |
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Trachoma (20) · Chlamydia Infections (5) · Bacterial Infections (3) · Elephantiasis, Filarial (2) · Eye Diseases (2) · Infections (2) · Communicable Diseases (1) · Diarrhea (1) · Health Education (1) · Malaria (1) · Neglected Diseases (1) · Respiratory Tract Infections (1) · Trichiasis (1)
Bacterial Infections and Mycoses (23) · Conjunctival Diseases (23) · Conjunctivitis (23) · Eye Infections (23) · Eye Infections, Bacterial (23) · Eye Diseases (21) · Infections (21) · Bacterial Infections (20) · Chlamydiaceae Infections (20) · Corneal Diseases (20) · Gram-Negative Bacterial Infections (20) · Chlamydia Infections (15) · Communicable Diseases (5) · Genital Diseases (5)
Azithromycin (12) · Ivermectin (2) · Moxifloxacin (2) · Albendazole (1) · Amoxicillin (1) · Gatifloxacin (1) · Ophthalmic Solutions (1) · Permethrin (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · Water (1)
University of California, San Francisco (10) · Johns Hopkins University (4) · Emory University (3) · London School of Hygiene and Tropical Medicine (3) · Alcon Research (2) · Allergan (1)
United States (12) · Ethiopia (6) · Niger (3) · United Kingdom (3) · Tanzania (2) · Burkina Faso (1) · Canada (1) · Democratic Republic of the Congo (1) · Malawi (1) · Mozambique (1) · South Sudan (1)
Tom Lietman, MD (3) · Catherine Oldenburg, ScD, MPH (2) · Elodie Lebas, RN (2) · Julius Schachter, PhD (2) · Kieran S O'Brien, MPH (2) · Paul Emerson, PhD (2) · Sheila K West (2) · Thomas M Lietman, MD (2) · Tom M Lietman, MD (2) · Abdou Amza, MD (1) · Catherine E Oldenburg, ScD (1) · Chandler R Dawson, MD (1) · Elodie J Lebas, RN (1) · Hadley Burroughs, MSPH (1) · Huub C Gelderblom, MD, PhD, MPH (1)
PMID 16905024, PMID 19329003, PMID 21072224, PMID 21685340, PMID 22095569, PMID 22180732, PMID 22192488, PMID 22545165, PMID 22736616, PMID 22953007, PMID 23326612, PMID 23392481, PMID 23785525, PMID 24433194, PMID 24621121, PMID 25002297, PMID 25407464, PMID 25858004, PMID 26302380, PMID 26489933, PMID 27956455, PMID 28351345, PMID 28402408, PMID 28893761, PMID 29088030, PMID 29260659, PMID 29561511, PMID 29897440, PMID 30014828, PMID 30106956, PMID 30151409, PMID 30419040, PMID 30515431, PMID 30689671, PMID 30895203, PMID 30950493, PMID 31166952, PMID 31237871, PMID 31362969, PMID 31589610, PMID 31796025, PMID 32556194, PMID 33407263, PMID 34559801, PMID 34967883, PMID 35156069, PMID 35190534, PMID 35997979, PMID 36747194, PMID 37021692
5UG1EY030833 (2), R01AI048789 (2), 1UG1EY028088 (1)