64 completed, 46 unknown, 30 recruiting, 15 not yet recruiting. 60 Not applicable, 29 Phase 2, 23 Phase 1, 10 Phase 3, 2 Early Phase 1.
Follow Colo-rectal Cancer: new trials by email Literature Review of Colo-rectal Cancer trials Research Report on Colo-rectal Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients Nurse-led Geriatric Assessment - Colo-rectal Cancer | Not applicable | Not yet recruiting | Helse Stavanger HF | 50 | 2026-09-28 | 2026-10-14 |
| Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis Radiogenomic and Immune Profiling, Prospective Radiogenomic and ctDNA Profiling - Colo-rectal Cancer, Liver Metastases | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 210 | 2026-09-01 | 2026-08-06 | |
| Early Discharge After Colorectal Surgery Cancer, Colo-rectal Cancer | Not yet recruiting | Fundación para la Investigación del Hospital Clínico de Valencia | 97 | 2026-09-01 | 2026-09-18 | |
| Prehabilitation in High-risk Oncologic Surgery Multidisciplinary Prehabilitation Program - Pancreatic Cancer, Colo-rectal Cancer | Not applicable | Recruiting | Fox Chase Cancer Center | 180 | 2026-07-15 | 2026-09-21 |
| Colorectal Cancer Screening Outreach Bundled messaging intervention - Colo-rectal Cancer | Not applicable | Recruiting | Yale University | 2000 | 2026-06-23 | 2026-07-07 |
| Decision Counseling and Follow-up for Shield+ Patients Decision Counseling Session - Colo-rectal Cancer | Not yet recruiting | Guardant Health, Inc. | 350 | 2026-06-01 | 2026-06-02 | |
| FULIRI Plus Targeted Therapy for First-line Conversion Therapy of Colorectal Cancer Liver Metastases. FULIRI combination targeted therapy - Colo-rectal Cancer | Phase 2 | Not yet recruiting | Zhongnan Hospital | 24 | 2026-06-01 | 2026-04-07 |
| A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE) Cemiplimab, cemiplimab plus fianlimab, cemiplimab + REGN7075 - Colo-rectal Cancer | Phase 2 | Recruiting | NSABP Foundation Inc | 79 | 2026-04-17 | 2026-09-03 |
| The Impact of AI-Assisted Nursing Care Intervention Within the Enhanced Recovery Framework on Outcomes of Colorectal Surgery Patients Educational intervention, Standard maintenance therapy - Home Care, Enhanced Recovery | Not applicable | Active not recruiting | Bahçeşehir University | 70 | 2026-04-10 | 2026-06-09 |
| Serum Talin-1 and Cripto-1 in Colorectal Cancer Serum level of Human Talin-1, Serum level of Human Cripto-1 - Colo-rectal Cancer | Not applicable | Not yet recruiting | Assiut University | 70 | 2026-03-30 | 2026-02-17 |
| Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy Colonoscopy Surveillance - Advanced Colorectal Cancer, Colo-rectal Cancer | Enrolling by invitation | National Taiwan University Hospital | 1274 | 2026-03-10 | 2026-03-13 | |
| Post Operative Hospital at Home After Colorectal Surgery virtual Hospital at Home - Colo-rectal Cancer, Colo-rectal Surgery | Not applicable | Not yet recruiting | Nordsjaellands Hospital | 20 | 2025-12-15 | 2025-08-11 |
| Piecemeal Resection and Advanced Histology Independently Predict Local Recurrence After Colorectal Snare-based Endoscopic Resection: a Time-to-event Cohort Study Colo-rectal Cancer | Completed | University of Sao Paulo | 255 | 2025-12-04 | 2026-03-03 | |
| Clinical Study on the Expression of PHGDH and Its Prognostic Value in Colorectal Cancer Patients Receiving Immunotherapy No intervention - Colo-rectal Cancer | Completed | West China Hospital | 100 | 2025-11-01 | 2026-04-02 | |
| The AIDPRO-CRC Trial AI augmented risk-stratification, Expert-based Risk-stratification - Colo-rectal Cancer | Not applicable | Recruiting | Zealand University Hospital | 1200 | 2025-10-24 | 2026-09-17 |
| A Study to Characterize Encorafenib Plus Cetuximab as Rechallenge Treatment for BRAF V600E-mutant Metastatic Colorectal Cancer Patients After Previous Therapy With BRAF Inhibitors-based Combinations Rechalange with bevacizumab + encorafenib - Colo-rectal Cancer | Phase 2 | Not yet recruiting | Vall d'Hebron Institute of Oncology | 25 | 2025-10-01 | 2025-09-17 |
| Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors ADC - Prostate Cancer Castration-resistant Prostate Cancer, Breast Cancer | Phase 1 / Phase 2 | Recruiting | MBrace Therapeutics | 150 | 2025-09-03 | 2026-02-17 |
| Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49 Colonoscopy, Shared Decision-Making - Colo-rectal Cancer, Shared Decision Making | Not applicable | Enrolling by invitation | National Taiwan University Hospital | 2286 | 2025-09-01 | 2026-03-31 |
| A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors ALX2004 - NSCLC (Advanced Non-small Cell Lung Cancer), HNSCC | Phase 1 | Recruiting | ALX Oncology Inc. | 170 | 2025-08-18 | 2026-09-30 |
| Study on the Prediction of Regional Lymph Node Metastasis in Colorectal Cancer by Spectral CT Combined With MSI Investigating the role of spectral CT combined with MSI status in the diagnosis and treatment of colorectal cancer lymph nodes. - Colo-rectal Cancer | Not applicable | Active not recruiting | Yunnan Cancer Hospital | 260 | 2025-08-04 | 2026-05-04 |
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Colonic Neoplasms (183) · Colorectal Neoplasms (36) · Breast Neoplasms (17) · Pancreatic Neoplasms (15) · Rectal Neoplasms (15) · Stomach Neoplasms (14) · Lung Neoplasms (12) · Colonic Polyps (10) · Neoplasms (10) · Ovarian Neoplasms (10) · Carcinoma, Non-Small-Cell Lung (9) · Melanoma (7) · Esophageal Neoplasms (6) · Head and Neck Neoplasms (6) · Neoplasm Metastasis (6)
Intestinal Neoplasms (183) · Neoplasms by Site (183) · Digestive System Diseases (182) · Digestive System Neoplasms (182) · Gastrointestinal Diseases (182) · Intestinal Diseases (182) · Gastrointestinal Neoplasms (181) · Colonic Diseases (180) · Neoplasms (173) · Colorectal Neoplasms (147) · Rectal Diseases (47) · Pathological Conditions, Signs and Symptoms (36) · Lung Diseases (23) · Respiratory Tract Diseases (23) · Endocrine System Diseases (21)
Oxaliplatin (8) · Irinotecan (5) · Leucovorin (5) · Bevacizumab (4) · Cetuximab (4) · Fluorouracil (4) · pembrolizumab (4) · Blood Specimen Collection (3) · Capecitabine (3) · Colonoscopy (3) · HMPL-013 (3) · tislelizumab (3) · Cyclophosphamide (2) · Endoscopic Mucosal Resection (2) · Radiotherapy (2)
Assiut University (7) · Check-Cap Ltd. (3) · National Taiwan University Hospital (3) · Roswell Park Cancer Institute (3) · Seoul National University Hospital (3) · West China Hospital (3) · Centre hospitalier de l'Université de Montréal (CHUM) (2) · Chinese Academy of Medical Sciences (2) · Corporacion Parc Tauli (2) · Dr. Horst Schmidt Klinik GmbH (2) · Exact Sciences Corporation (2) · Guardant Health, Inc. (2) · Imperial College London (2) · London North West Healthcare NHS Trust (2) · Mirati Therapeutics Inc. (2)
United States (49) · China (21) · France (12) · Italy (11) · Egypt (9) · Canada (8) · United Kingdom (8) · Denmark (7) · Germany (7) · Turkey (Türkiye) (7) · South Korea (6) · Spain (6) · Taiwan (5) · Brazil (4) · Sweden (4)
Boaz Shpigelman (2) · Gina Brown, MD (2) · Ralf Kiesslich, Prof. (2) · Shai Friedland, MD (2) · Adjoa Anyane-Yeboa, MD, MPH (1) · Ahmed M Mahmoud, Professor (1) · Aiping Zhou, Doctor (1) · Ajay Goel, PhD (1) · Albert Yu, MD (1) · Alexander Vahrmeijer, MD, PhD (1) · Alice Bexon, MD (1) · Ankit Sarin, MD (1) · Antonio Camargo, PhD (1)
PMID 11875733, PMID 12719744, PMID 12800205, PMID 15551359, PMID 15896435, PMID 17224254, PMID 18323549, PMID 18469262, PMID 18473397, PMID 20477993, PMID 21392504, PMID 22436836, PMID 23017624, PMID 23357886, PMID 24032114, PMID 24090728, PMID 24105007, PMID 24278855, PMID 24671869, PMID 24857018, PMID 25467588, PMID 26171439, PMID 27005802, PMID 27032509, PMID 27811855, PMID 27908600, PMID 28228123, PMID 28494577, PMID 28779355, PMID 29343246, PMID 29352577, PMID 29470704, PMID 29881409, PMID 30123367, PMID 30426190, PMID 30658268, PMID 30911655, PMID 31323292, PMID 31380561, PMID 31434774, PMID 31631858, PMID 31820199, PMID 31836474, PMID 32012053, PMID 32044092, PMID 32122632, PMID 32183229, PMID 32477640, PMID 32542873, PMID 32572858
2023 (3), R01CA207689 (2), 2017 (1), 2019 (1), P50CA244433 (1)