20 completed, 5 active not recruiting, 5 recruiting, 5 terminated. 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endometrial Cancer Vaginal Fluid Specimen Collection Study Abnormal Uterine Bleeding (AUB), Endometrial Cancer | Active not recruiting | Exact Sciences Corporation | 4200 | 2026-03-10 | 2026-10-05 | |
| Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests Patient survey - Gastro Esophageal Reflux Disease, Barrett Esophagus | Recruiting | University of Colorado, Denver | 556 | 2024-11-01 | 2024-11-18 | |
| Falcon Real World Evidence Registry Exact Sciences Multicancer Early Detection (MCED) Test - Cancer | Recruiting | Exact Sciences Corporation | 25000 | 2024-08-01 | 2026-09-11 | |
| EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD) ctDNA MRD test - Breast Cancer | Recruiting | Exact Sciences Corporation | 1800 | 2024-06-07 | 2026-01-20 | |
| Stool Sample Collection Study A screening device for the detection of colorectal and other aerodigestive tract cancers - Colorectal Cancer | Unknown | Innovis LLC | 40 | 2023-07-20 | 2024-03-06 | |
| First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer MRD - Colorectal Cancer | Active not recruiting | Exact Sciences Corporation | 416 | 2023-06-20 | 2025-07-24 | |
| The T-REX Trial: Tailored Regional External Beam Radiotherapy in Clinically Node-negative Breast Cancer Patients With 1-2 Sentinel Node Macrometastases. De-escalation - Breast Cancer | Not applicable | Recruiting | Region Skane | 1350 | 2023-03-17 | 2026-05-11 |
| Informed Choice - Compass Brief Video, Brief Video Plus - Colorectal Cancer | Terminated | Exact Sciences Corporation | 1823 | 2022-04-28 | 2025-11-10 | |
| Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients Biospecimen Collection, Electronic Health Record Review - Colorectal Carcinoma, Lynch Syndrome | Recruiting | Mayo Clinic | 950 | 2022-03-30 | 2026-08-18 | |
| CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer MRD - Colorectal Cancer | Active not recruiting | Exact Sciences Corporation | 1017 | 2021-12-15 | 2026-01-12 | |
| ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk Study CT/MRI Imaging, Standard of Care CT/MRI Imaging, Oncoguard™ Liver Test - Hepatocellular Carcinoma, Hepatocellular Cancer | Active not recruiting | Exact Sciences Corporation | 2990 | 2021-07-26 | 2025-10-15 | |
| Stool Collection Sub-Study of Exact Sciences Protocol 2018-01 Stool Sample Collection - Colorectal Cancer, Colo-rectal Cancer | Completed | Exact Sciences Corporation | 291 | 2020-07-21 | 2022-06-06 | |
| Home Usability Study of the SARS-CoV-2 (COVID-19) Test SARS-CoV-2 - COVID-19 | Completed | Exact Sciences Corporation | 30 | 2020-05-18 | 2023-12-13 | |
| Detecting Cancers Earlier Through Elective Plasma-based CancerSEEK Testing Early Cancer Detection | Completed | Exact Sciences Corporation | 6400 | 2019-11-18 | 2024-06-14 | |
| Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C" mt-sDNA 2.0 screening test, FIT test, Colonoscopy - Colorectal Cancer | Completed | Exact Sciences Corporation | 26758 | 2019-11-15 | 2023-09-01 | |
| Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: "Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C" Blood Sample Collection - Colorectal Cancer | Completed | Exact Sciences Corporation | 23494 | 2019-11-15 | 2023-09-28 | |
| Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality Cologuard - Colon Cancer | Active not recruiting | Exact Sciences Corporation | 150000 | 2019-10-18 | 2025-10-03 | |
| Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Melanoma Blood Sample Collection - Melanoma | Terminated | Exact Sciences Corporation | 348 | 2019-01-10 | 2021-02-10 | |
| Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act Bold Colorectal Cancer | Completed | Exact Sciences Corporation | 5131 | 2019-01-03 | 2020-07-21 | |
| Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast Colorectal Cancer | Completed | Exact Sciences Corporation | 850 | 2018-12-20 | 2025-06-29 |
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Colorectal Neoplasms (20) · Neoplasms (8) · Colonic Diseases (6) · Digestive System Diseases (6) · Digestive System Neoplasms (6) · Gastrointestinal Diseases (6) · Gastrointestinal Neoplasms (6) · Intestinal Diseases (6) · Intestinal Neoplasms (6) · Neoplasms by Site (6) · Rectal Diseases (5) · Breast Neoplasms (3) · Colonic Neoplasms (3) · Barrett Esophagus (2) · Carcinoma, Hepatocellular (2)
Colonoscopy (2) · Biopsy (1) · Endoscopy (1) · Specimen Handling (1)
United States (34) · Canada (8) · Italy (2) · Spain (2) · Finland (1) · France (1) · Germany (1) · Israel (1) · Japan (1) · Norway (1) · Sweden (1) · Taiwan (1) · Thailand (1) · United Kingdom (1)
Thomas Imperiale, MD (5) · Graham Lidgard, PhD (3) · Laura Strong (3) · Binu John (1) · Charles R. Rogers, PhD (1) · Dax Kurbegov, MD (1) · Gregg S Britt (1) · Jennifer Kolb, MD, MS (1) · Joan M. Griffin, PhD (1) · John Inadomi, MD (1) · Michael Domanico (1) · Niloy Jewel Samadder, M.D. (1) · Prasad G Iyer, M.D. (1) · Sachin Wani, MD (1) · Sara Alkner, Associate professor (1)
PMID 23639600, PMID 39280922, PMID 24645800, PMID 29891853, PMID 32128228, PMID 32889146, PMID 33436397, PMID 33857451, PMID 34391922, PMID 35842109, PMID 37502338, PMID 37751948, PMID 37851937, PMID 38224564, PMID 38477986, PMID 38513982, PMID 39019622, PMID 40525978, PMID 42800682
P30CA015083 (1)