14 completed, 3 not yet recruiting, 3 terminated, 1 unknown. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 14, Not yet recruiting 3, Terminated 3, Unknown 1 |
Follow Chronic Rhinosinusitis: new trials by email Literature Review of Chronic Rhinosinusitis trials Research Report on Chronic Rhinosinusitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bactorinol® Nasal Spray With Reduced-Dose Mometasone in Adults With Chronic Rhinosinusitis Bactorinol® (manufacturer: PharmExtracta S.p.A.), Mometasone Furoate Nasal Spray - Chronic Rhinosinusitis | Not applicable | Not yet recruiting | Liaquat University of Medical & Health Sciences | 78 | 2026-09-14 | 2026-09-02 |
| Efficacy Of Erythromycin Phonophoresis on Chronic Rhinosinusitis Erythromycin Phonophoresis, Ultrasound (US), Topical Erythromycin - Chronic Rhinosinusitis | Not applicable | Not yet recruiting | Cairo University | 90 | 2025-07-07 | 2025-07-14 |
| The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS Conventional olfactory training device, Modified olfactory training device, Budesonide irrigation - Olfactory Dysfunction, Chronic Rhinosinusitis | Not applicable | Not yet recruiting | Peking University Third Hospital | 213 | 2025-03-14 | 2025-02-20 |
| Nigella Sativa for Selected Outcomes in Chronic Rhinosinusitis Nigella sativa nasal oil drops, standard treatment - Chronic Rhinosinusitis | Not applicable | Completed | Cairo University | 102 | 2022-08-07 | 2024-04-17 |
| Microcurrent Device (TIVIC Health) Microcurrent TENS device, Sham Device - Chronic Rhinosinusitis | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 60 | 2022-03-30 | 2025-06-12 |
| Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis Normal Saline Nasal Irrigation, Acetylcysteine (Mucomyst) Nasal Irrigation, Povidone-Iodine Nasal Irrigation - Chronic Rhinosinusitis | Not applicable | Completed | Pusan National University Hospital | 48 | 2021-10-13 | 2026-03-13 |
| Efficacy and Safety of Xylitol Nasal Irrigation After Functional Endoscopic Sinus Surgery Xylitol Powder, Salt Powder - Chronic Rhinosinusitis, Postoperative Care | Not applicable | Completed | Taichung Veterans General Hospital | 79 | 2020-02-01 | 2023-10-31 |
| Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP) Prednisone, Flonase - Chronic Rhinosinusitis, Endoscopic Sinus Surgery | Not applicable | Completed | Stanford University | 81 | 2015-08-01 | 2020-08-04 |
| Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement Early saline irrigation, Routine Irrigation - Chronic Rhinosinusitis | Not applicable | Completed | University of Alberta | 25 | 2015-05-01 | 2018-10-15 |
| Efficacy of Nasal Irrigation With Respimer® Netiflow® vs Saline Among Patients With Cystic Fibrosis and Chronic Rhinosinusitis Saline solution, Respimer Netiflow - Chronic Rhinosinusitis, Cystic Fibrosis | Not applicable | Unknown | Laboratoire de la Mer | 50 | 2015-01-01 | 2017-09-01 |
| NuVent™ Revision Study Electromagnetic Sinus Dilation System (NuVent™) - Chronic Rhinosinusitis | Not applicable | Completed | Medtronic Surgical Technologies | 51 | 2014-12-01 | 2016-08-24 |
| A Randomized Controlled Trial Evaluating Postoperative Debridement Following Endoscopic Sinus Surgery debridement - Chronic Rhinosinusitis | Not applicable | Completed | Unity Health Toronto | 30 | 2014-05-01 | 2019-02-06 |
| Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery Clarithromycin, Glucocorticoid - Chronic Rhinosinusitis, Endoscopic Sinus Surgery | Not applicable | Completed | Zheng Liu | 187 | 2014-01-01 | 2018-09-25 |
| Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease Low salicylate diet, Normal Diet - Chronic Rhinosinusitis, Aspirin Exacerbated Respiratory Disease | Not applicable | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 7 | 2013-05-01 | 2021-03-09 |
| Safety and Efficacy of Lactococcus Lactis Probiotic Bacteria for the Treatment of Chronic Rhinosinusitis Topical probiotic treatment with Lactococcus lactis W136, Saline irrigation - Chronic Rhinosinusitis | Not applicable | Completed | Centre hospitalier de l'Université de Montréal (CHUM) | 27 | 2013-03-06 | 2019-08-12 |
| Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis Relieva Balloon Sinuplasty™ System, Functional Endoscopic Sinus Surgery - Chronic Rhinosinusitis | Not applicable | Terminated | Integra LifeSciences Corporation | 25 | 2012-02-01 | 2024-07-11 |
| Impact of Topical Sinonasal Budesonide Irrigation on Hypothalamic-Pituitary-Adrenal Axis Function Budesonide irrigation - Chronic Rhinosinusitis | Not applicable | Terminated | Ottawa Hospital Research Institute | 2 | 2010-12-01 | 2012-05-18 |
| Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery. Propofol and Remifentanyl, Sevoflurane and Remifentanyl - Chronic Rhinosinusitis | Not applicable | Terminated | The University of Texas Health Science Center, Houston | 23 | 2010-05-01 | 2021-11-01 |
| Mucociliary Clearance Time in Chronic Rhinosinusitis (CRS) Patients After Sinus Surgery 1% Johnson's Baby Shampoo - Chronic Rhinosinusitis | Not applicable | Completed | The University of Texas Health Science Center, Houston | 60 | 2009-07-01 | 2010-03-22 |
| Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study Pre-treatment Sinus CT Scan, Post-treatment Sinus CT Scan - Chronic Rhinosinusitis | Not applicable | Completed | Northwestern University | 40 | 2009-03-01 | 2012-01-18 |
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Asthma (1) · Bronchiolitis Obliterans Syndrome (1) · Cystic Fibrosis (1) · Pain (1) · Pain, Postoperative (1) · Sinusitis (1)
Lung Diseases (3) · Respiratory Tract Diseases (3) · Bronchial Diseases (2) · Immune System Diseases (2) · Lung Diseases, Obstructive (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Genetic Diseases, Inborn (1) · Graft vs Host Disease (1)
Fluticasone (2) · Acetylcysteine (1) · Biopsy (1) · Clarithromycin (1) · Debridement (1) · Erythromycin (1) · Glucocorticoids (1) · Nasal Lavage (1) · Prednisone (1) · Propofol (1) · Remifentanil (1) · Saline Solution (1) · Sevoflurane (1) · Ultrasonography (1)
Cairo University (2) · The University of Texas Health Science Center, Houston (2) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Icahn School of Medicine at Mount Sinai (1) · Integra LifeSciences Corporation (1) · Laboratoire de la Mer (1) · Liaquat University of Medical & Health Sciences (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Massachusetts General Hospital (1) · Medtronic Surgical Technologies (1) · Northwestern University (1) · Ottawa Hospital Research Institute (1) · Peking University Third Hospital (1) · Pusan National University Hospital (1) · Stanford University (1)
United States (7) · Canada (5) · China (2) · Egypt (2) · France (1) · Italy (1) · South Korea (1) · Taiwan (1)
Adel El-Antably, Doctorate (1) · Alfred-Marc Iloreta, MD (1) · Aya Gamal Fawzy Elsayed, PhD (1) · Bassamat O. Ahmed, Doctorate (1) · Daniel Hamilos, MD (1) · Davide Cattano, MD PhD (1) · Fathy M. Soliman, Doctorate (1) · Hanan A. Al Sebaee, Doctorate (1) · Hussein Gamal Hussein Mogahed, PhD (1) · Ian Witterick, MD, MSc (1) · John Lee, MD, FRCSC (1) · Julia E Noel, MD (1) · Kilty Shaun, MD (1) · Leigh J Sowerby, MD (1) · Michael T Chang, MD (1)