19 completed, 15 not yet recruiting, 15 recruiting, 4 enrolling by invitation. 57 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 57 | Completed 19, Not yet recruiting 15, Recruiting 15, Enrolling by invitation 4, Unknown 3, Withdrawn 1 |
Follow Chronic Low Back Pain (CLBP): new trials by email Literature Review of Chronic Low Back Pain (CLBP) trials Research Report on Chronic Low Back Pain (CLBP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RE-SCALE: Rehabilitation Engagement and Scaled Access With eXtended Reality and Artificial Intelligence Mixed realities rehabilitation program, Usual Care - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Universitat Jaume I | 314 | 2027-01-01 | 2025-10-02 |
| Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment Engagement Among Medicaid-insured Adults With Chronic Low Back Pain Empowering Pain Psychology Access and Collaboration (EPPAC), Usual Care Pain Psychology Evaluation - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Johns Hopkins University | 70 | 2026-11-30 | 2026-10-26 |
| Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy EMMA (Expert Manipulative Massage Automation) - Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Mayo Clinic | 38 | 2026-11-01 | 2026-09-17 |
| SENECA - Smart Therapies for Chronic Pain VIVO 2nd GEN, Standard-of-Care Multimodal Pain Therapy - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Aurimod GmbH | 44 | 2026-09-17 | 2026-08-31 |
| Integration of Virtual Reality and Traditional Acupuncture: From Education to Clinical Practice. VR-Assisted Acupuncture Group, Traditional Acupuncture Group, Conventional Care / Outcome Assessment Only - Chronic Low Back Pain (cLBP) | Not applicable | Not yet recruiting | China Medical University Hospital | 90 | 2026-09-08 | 2026-09-14 |
| Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain Single Bipolar Ablation, Double Parallel Bipolar Ablation, Double Cross Bipolar Ablation - Low Back Pain, Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Axon srl | 69 | 2026-09-01 | 2026-07-10 |
| Biologic Injection For Adults With Lumbar Disc Herniation Bone Marrow Aspirate Concentrate (BMAC) - Degenerative Disc Disease, DDD | Not applicable | Recruiting | Weill Medical College of Cornell University | 90 | 2026-08-30 | 2026-07-29 |
| Lumbar Extension Strengthening in Addition to Manual Therapy and Exercise for Chronic Low Back Pain Standard Physical Therapy, Lumbar Extensor Strengthening plus Standard Physical Therapy - Chronic Low Back Pain (CLBP) | Not applicable | Enrolling by invitation | Brooke Army Medical Center | 60 | 2026-08-03 | 2026-07-22 |
| PRT for Chronic Low Back Pain Pain Reprocessing Therapy, Monitoring and Education - Chronic Low Back Pain (CLBP), Nociplastic Pain | Not applicable | Recruiting | University Health Network, Toronto | 30 | 2026-07-15 | 2026-10-06 |
| Chronic Low Back Pain Comorbidities: Unravelling Impaired Glucose Metabolism Glucose beverage, Isomaltulose beverage, Standardized breakfast - Chronic Low Back Pain (Non-specific, Uncomplicated), Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Vrije Universiteit Brussel | 124 | 2026-07-01 | 2026-07-29 |
| Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients Impairment-based trearment, Modified Functional restoration program - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Cairo University | 18 | 2026-07-01 | 2026-07-13 |
| Focal Extracorporeal Shock Wave Therapy With Two Different Dosing Regimens for Chronic Low Back Pain Focal Extracorporeal Shock Wave Therapy (F-ESWT) - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Armando Tonatiuh Avila Garcia | 60 | 2026-06-15 | 2026-06-12 |
| Pain Neuroscience Education for Chronic Pain Therapeutic Exercise and Education in Pain Neuroscience, Therapeutic exercise and education in the neuroscience of pain: the placebo effect - Fibromyalgia (FM), Chronic Low Back Pain (CLBP) | Not applicable | Enrolling by invitation | University of Valencia | 84 | 2026-05-05 | 2026-07-09 |
| Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain. Electroacupuncture, Auricular Acupressure, Sham Auricular Acupressure - Chronic Low Back Pain (CLBP), Lumbar Spondylosis | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 76 | 2026-04-20 | 2026-08-14 |
| Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain Connective tissue dry needling, Exercise therapy - Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction | Not applicable | Not yet recruiting | University of Social Welfare and Rehabilitation Science | 42 | 2026-04-10 | 2026-01-21 |
| Chronic Low Back Pain and Osteopathic Manipulation Treatment Usual VA Care, Osteopathic manipulative treatment - Chronic Low Back Pain (CLBP), Low Back Pain | Not applicable | Recruiting | Edward Hines Jr. VA Hospital | 48 | 2026-03-02 | 2026-05-22 |
| A Superiority Trial of Radiofrequency Ablation for Low Back Pain Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation - Chronic Low Back Pain (CLBP) | Not applicable | Recruiting | University of Washington | 300 | 2026-02-04 | 2026-02-09 |
| Percussive Massage Therapy Using Heat Attachment in Chronic Low Back Pain Percussive Massage Therapy, Exercise Training (Conventional Rehabilitation), Transcutaneous Electrical Nerve Stimulation (Conventional Rehabilitation) - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Fenerbahce University | 48 | 2026-01-12 | 2026-01-16 |
| Effectiveness of ELDOA Stretching Combined With Standard Physiotherapy in Adults With Chronic Low Back Pain and Dural Hypomobility; A Randomized Controlled Trial. ELDOA Stretching, Standard Physiotherapy - Chronic Low Back Pain (CLBP) | Not applicable | Completed | Ibadat International University, Islamabad | 48 | 2026-01-10 | 2026-07-28 |
| Clinical Research on the Comparative Effectiveness and Safety of JHG002 Therapy for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial Hominis placental pharmacopuncture, Tanscutaneous electrical nerve stimulation (TENS) - Chronic Low Back Pain (CLBP) | Not applicable | Recruiting | Jaseng Medical Foundation | 96 | 2025-12-17 | 2026-02-25 |
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Low Back Pain (18) · Chronic Pain (9) · Motor Activity (5) · Kinesiophobia (3) · Back Pain (2) · Fibromyalgia (2) · Inflammation (2) · Intervertebral Disc Displacement (2) · Myofascial Pain Syndromes (2) · Pain (2) · Agnosia (1) · Anxiety Disorders (1) · Behavior (1) · Connective Tissue Diseases (1) · Depression (1)
Pathological Conditions, Signs and Symptoms (27) · Neurologic Manifestations (26) · Signs and Symptoms (26) · Pain (24) · Back Pain (17) · Musculoskeletal Diseases (8) · Behavior (5) · Muscular Diseases (5) · Mental Disorders (4) · Anxiety Disorders (3) · Bone Diseases (3) · Nervous System Diseases (3) · Phobic Disorders (3) · Spinal Diseases (3) · Hernia (2)
Exercise (3) · Exercise Therapy (3) · Educational Status (2) · Manipulation, Osteopathic (2) · Transcutaneous Electric Nerve Stimulation (2) · Anti-Inflammatory Agents, Non-Steroidal (1) · Diagnosis-Related Groups (1) · Diathermy (1) · Dry Needling (1) · Electroacupuncture (1) · Endurance Training (1) · High-Energy Shock Waves (1) · Ibuprofen (1) · Manipulation, Spinal (1) · Muscle Stretching Exercises (1)
Cairo University (3) · University of Lahore (3) · Hopital Charles Nicolle (2) · McGill University (2) · The Hong Kong Polytechnic University (2) · University of Medicine and Pharmacy at Ho Chi Minh City (2) · Armando Tonatiuh Avila Garcia (1) · Aurimod GmbH (1) · Axon srl (1) · Beth Israel Deaconess Medical Center (1) · Brooke Army Medical Center (1) · Cardenal Herrera University (1) · China Medical University Hospital (1) · Edward Hines Jr. VA Hospital (1) · Edward Via Virginia College of Osteopathic Medicine (1)
United States (14) · Pakistan (7) · Turkey (Türkiye) (4) · Belgium (3) · Canada (3) · Egypt (2) · Hong Kong (2) · Italy (2) · Saudi Arabia (2) · South Korea (2) · Spain (2) · Tunisia (2) · Vietnam (2) · Austria (1) · France (1)
An De Groef, Doctoral degree (1) · Andrea D Furlan, MD PhD (1) · Benjamin Hando, PT, DSc, PhD (1) · Billy CL So, Prof. (1) · Daniel Cawley, DC, MS, MSHS (1) · Dennis E Anderson, Ph.D. (1) · Divya Adhia, Ph.D (1) · Emanuele Piras, MD (1) · Fenan S Rassu, Ph.D. (1) · Hatoma Fatima Malik, DPT (1) · Janna Friedly, MD (1) · Jo Nijs, Professor (1) · John Sturgeon, PhD (1) · Kerstin Palombero, PhD (1)
PMID 11717207, PMID 11967233, PMID 12467083, PMID 15628774, PMID 16244008, PMID 16511830, PMID 16550448, PMID 16618043, PMID 16886014, PMID 21276188, PMID 22030379, PMID 23959791, PMID 24175954, PMID 25026138, PMID 25932092, PMID 27745712, PMID 28476690, PMID 29306764, PMID 29499728, PMID 29573870, PMID 30402136, PMID 30546064, PMID 30930578, PMID 32123652, PMID 32516195, PMID 33992245, PMID 36110466, PMID 36169931, PMID 36775506, PMID 37217536, PMID 37798990, PMID 38574213, PMID 40299187, PMID 40850927, PMID 41212507, PMID 5034102, PMID 9306535
K23MD019351 (1), T32AG023480 (1), U01AR084723 (1)