12 completed, 5 recruiting, 4 not yet recruiting, 1 active not recruiting. 15 Not applicable, 2 Early Phase 1, 2 Phase 1, 1 Phase 3, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health Olives - Healthy Diet, Cholesterol | Not applicable | Not yet recruiting | Yale University | 226 | 2027-01-01 | 2026-05-13 |
| Enhancing Mental and Physical Health of Women Veterans 3.0 EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF) - Cardiovascular Diseases, Overweight | Not applicable | Not yet recruiting | VA Office of Research and Development | 18 | 2026-10-01 | 2026-01-21 |
| Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control - Cardiovascular Diseases, Blood Pressure | Not applicable | Not yet recruiting | University of Montana | 154 | 2026-08-01 | 2026-04-20 |
| A Study on the Efficacy of 2% Cholesterol Cream in Atopic Dermatitis Topical 2% cholesterol cream, Placebo Vehicle Cream - Atopic Dermatitis (AD), Cholesterol | Not applicable | Enrolling by invitation | Institute of Dermatology, Thailand | 30 | 2026-04-01 | 2026-05-14 |
| Effect of Curd Cheese on Metabolic Health in Adults Curd Cheese Supplemented Diet - Cholesterol, Lipid Profile | Not applicable | Completed | Süleyman Kılıç | 44 | 2025-12-12 | 2026-06-30 |
| Interprofessional Pharmacogenomics (IPGx) Registry and Repository Diabetes, Cholesterol | Recruiting | Texas A&M University | 3000 | 2025-11-01 | 2025-09-12 | |
| The Effect of a Digital Heart Health App and Lifestyle Intervention for Heart Disease in Primary Care. Digital Heart Health Program - Cardiovascular Diseases, Cardiovascular Risk Factors | Not applicable | Recruiting | University of Toronto | 1100 | 2025-08-15 | 2025-11-26 |
| Whey Protein Comparisons for Blood Lipid Effects Standard whey, Hydrolyzed whey - Cholesterol | Not applicable | Completed | Medinutra LLC | 60 | 2025-08-05 | 2026-07-14 |
| Natural Heart Health Supplement Trial Heart Health Supplement - Cholesterol, Cholesterol (total and HDL) | Phase 1 | Not yet recruiting | Efforia, Inc | 60 | 2025-01-15 | 2024-11-04 |
| AlmegaPL CV Health Open Label Study AlmegaPL (FDA NDIN # 826) - Cholesterol, Triglycerides | Phase 4 | Completed | Qualitas Health | 250 | 2022-05-11 | 2024-02-14 |
| Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4) Dexamethasone (Group 2), Cosyntropin (Group 3), PET/CT Scan with FNP-59 - Radiotracer, Hypertension | Early Phase 1 | Recruiting | Benjamin Viglianti | 24 | 2021-11-01 | 2025-12-05 |
| Enhancing Mental and Physical Health of Women Veterans EBQI, REP - Cardiovascular Diseases, Overweight | Not applicable | Active not recruiting | VA Office of Research and Development | 20 | 2021-10-21 | 2026-09-14 |
| Identification of Asymptomatic Patients at Very High Cardiovascular Risk: Contribution of a Strategy Based on Carotid and Coronary Explorations, Compared to Simple Risk Calculation Using the European "SCORE 2" Algorithm. (IDEA-CVR) SCORE2 - Myocardial Infarction, Atheroma | Recruiting | Elsan | 1000 | 2021-09-12 | 2025-11-28 | |
| Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1) FNP-59 - Radiotracer, Hypertension | Early Phase 1 | Recruiting | Benjamin Viglianti | 6 | 2021-01-18 | 2025-12-05 |
| Dietary Cholesterol and Adipose Tissue Inflammation Added Cholesterol, No Added Cholesterol - Cholesterol | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2019-10-01 | 2019-11-04 | |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease There is no intervention in this study - Gut Microbiome, Gastrointestinal Microbiome | Suspended | ProgenaBiome | 1000 | 2019-07-11 | 2026-09-21 | |
| Singing Groups for Seniors: Well-Being, Cognitive Function and Health Singing Group Intervention Program, Alternative Social and Leisure Activities - Cognitive Function, Well-Being | Not applicable | Completed | Iolanda Costa Galinha | 140 | 2018-12-05 | 2023-05-10 |
| Clinical Trial to Evaluate the Reduction of Cardiovascular Risk Apigenin, luteonin, grapefruit extract and citrolive, maltodextrina - Cholesterol | Not applicable | Completed | Universidad Católica San Antonio de Murcia | 100 | 2016-10-01 | 2019-10-03 |
| Efficacy of Lactobacillus Mucosae DPC6426 on Blood-lipids Placebo, Lactobacillus mucosae DPC6426 - Cholesterol, Hypercholesterolaemia | Not applicable | Completed | University College Cork | 94 | 2016-05-30 | 2026-04-09 |
| Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol Dietary control of protein and fiber intake at breakfast - Brain Activity, Appetite | Not applicable | Completed | Purdue University | 20 | 2014-03-01 | 2016-02-05 |
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Diabetes Mellitus (5) · Cardiovascular Diseases (4) · Hypertension (4) · Depression (3) · Health Behavior (3) · Hypercholesterolemia (3) · Anxiety Disorders (2) · Hyperlipidemias (2) · Neoplasms (2) · Obesity (2) · Overweight (2) · Patient Participation (2) · Patient Preference (2) · Patient Satisfaction (2) · Prediabetic State (2)
Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10) · Pathological Conditions, Signs and Symptoms (7) · Behavior (6) · Endocrine System Diseases (6) · Glucose Metabolism Disorders (6) · Vascular Diseases (6) · Cardiovascular Diseases (5) · Pathologic Processes (5) · Dyslipidemias (4) · Lipid Metabolism Disorders (4) · Mental Disorders (4) · Signs and Symptoms (4) · Behavioral Symptoms (3) · Patient Acceptance of Health Care (3)
Ezetimibe (3) · Apigenin (1) · Chromosomes, Artificial, P1 Bacteriophage (1) · Cosyntropin (1) · Dexamethasone (1) · Educational Status (1) · Simvastatin (1) · grapefruit seed extract (1)
Benjamin Viglianti (2) · Organon and Co (2) · VA Office of Research and Development (2) · Efforia, Inc (1) · Elsan (1) · Institute of Dermatology, Thailand (1) · Instituto Aragones de Ciencias de la Salud (1) · Integrative Health Technologies, Inc. (1) · Iolanda Costa Galinha (1) · Medinutra LLC (1) · Mercer University (1) · ProgenaBiome (1) · Purdue University (1) · Qualitas Health (1) · Süleyman Kılıç (1)
United States (15) · Canada (1) · France (1) · Ireland (1) · Portugal (1) · South Korea (1) · Spain (1) · Thailand (1) · Turkey (Türkiye) (1)
Alison B Hamilton, PhD MPH (2) · Ben Viglianti, M.D, Ph.D. (1) · Benjamin L Viglianti, M.D, Ph.D. (1) · Bevanne A Bean-Mayberry, MD MHS (1) · Chavalit Supsrisunjai, MD, PhD (1) · Corrie Whisner, PhD (1) · Eghogho H Etomi, MSc (1) · Eneko Ganuza Taberna, PhD (1) · Erin P Finley, PhD MPH (1) · Fernando Civeira, MD, PhD (1) · Gilbert R Kaats, PhD FACN (1) · Harry G Preuss, MD MACN (1) · Iolanda C. Galinha, Ph.D, (1)
PMID 17086017, PMID 19380898, PMID 24019397, PMID 26232911, PMID 32948120, PMID 34355628, PMID 34378330, PMID 35483736, PMID 36890587, PMID 38379539, PMID 38907331, PMID 39180036, PMID 40410822
I01RD000411 (1)