197 completed, 23 recruiting, 20 unknown, 9 not yet recruiting. 197 Not applicable, 14 Phase 1, 11 Phase 2, 11 Phase 4, 2 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Home-Based Lower-Extremity Heat Therapy for Walking Function in Peripheral Artery Disease Lower-Extremity Heat Therapy, Sham Lower-Extremity Heat Therapy - PAD, PAD - Peripheral Arterial Disease | Not applicable | Not yet recruiting | Aquilo Sports, LLC | 40 | 2027-01-01 | 2026-06-17 |
| Whole Food Fibers for Support of Key Gut Bacteria for Human Health Whole food fiber mixture, inulin - Prediabetes or Overweight | Not applicable | Not yet recruiting | Purdue University | 24 | 2026-11-01 | 2026-09-24 |
| INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden INTEGRATE-RX - HIV, Hypertension | Not applicable | Not yet recruiting | Temple University | 450 | 2026-10-01 | 2026-07-17 |
| Effects of Transcutaneous Vagus Nerve Stimulation on Pain and Brain Activity in Healthy Adults Active transcutaneous vagus nerve stimulation, Sham transcutaneous vagus nerve stimulation, Cold pressor test - Acute Pain, Pain Perception | Not applicable | Not yet recruiting | David A. Purger | 20 | 2026-09-01 | 2026-09-18 |
| Respiratory and Real-time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion Carbon Dioxide, Mechano-acoustic device - Exercise-Induced Vocal Cord Dysfunction, Paradoxical Vocal Fold Motion | Phase 2 | Recruiting | Indiana University | 130 | 2026-08-12 | 2026-08-14 |
| Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention ED-SMART intervention, Substance use information - Substance Use (Drugs, Alcohol) | Not applicable | Enrolling by invitation | Purdue University | 650 | 2026-06-17 | 2026-07-23 |
| A1-Free vs. Conventional Milk Metabolic Response Study Lactose-Containing A1-Free Milk, Lactose-Containing Conventional Milk, Lactose-Free A1-Free Milk With Delayed Lactose Drink - Postprandial Glucose Response, Insulin Response | Not applicable | Not yet recruiting | Purdue University | 35 | 2026-06-15 | 2026-05-05 |
| Improving Dietary Quality Through Animal Source Protein Accessibility in a Low-Resource Setting Nutrition Secure Indianapolis Food Box Intervention, Nutrition Secure Indianapolis Nutrition Education - Nutrition Intervention, Healthy Eating | Not applicable | Enrolling by invitation | Purdue University | 500 | 2026-05-14 | 2026-06-02 |
| Slowly Digestible Carbohydrates for GLP-1 Secretion Maltodextrin (Placebo), Raw Corn Starch - Blood Glucose, GLP-1 | Not applicable | Recruiting | Purdue University | 19 | 2026-05-01 | 2026-05-07 |
| Social Robots Empowering Patients robot-guided curriculum, Video-guided curriumlum - Healthy Adult, Chinese | Not applicable | Completed | Northwestern University | 50 | 2026-01-30 | 2026-08-17 |
| Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated Malaria Artemether lumefantrine tablets, Artemether Lumefantrine and Imatinib Mesylate - Malaria (Plasmodium Falciparum) | Phase 2 | Recruiting | Victoria Biomedical Research Institute | 1116 | 2026-01-20 | 2026-06-29 |
| Real World Assessment of Resistance Breathing Device Stress, Breathing Exercise | Completed | Livotion, LLC | 73 | 2025-12-01 | 2026-04-13 | |
| Smart Soft Contact Lenses for Monitoring Glaucoma Bare Contact Lens, Experimental Smart Contact Lens, Commercially available smart contact lens - Glaucoma | Not applicable | Enrolling by invitation | Indiana University | 120 | 2025-10-19 | 2026-08-25 |
| Evaluating a Deep Neural Noise-Reduction Algorithm for Hearing Aids Hearing Aid Noise Reduction - Off, Hearing Aid Noise Reduction - Low, Hearing Aid Noise Reduction - High - Hearing Loss, Cochlear | Not applicable | Recruiting | Purdue University | 50 | 2025-10-16 | 2025-12-17 |
| Hormonal Contraception Access Through Pharmacist Prescribing Implementation HAPPI software - Contraception, Pharmaceutical Services | Not applicable | Recruiting | EMPOWERX INC | 150 | 2025-10-09 | 2025-12-04 |
| Can Listening to Music Improve Attention and Language After Post-Stroke Aphasia? Music-Based Therapy for Post Stroke Aphasia, Audiobook Intervention for Post Stroke Aphasia - Aphasia, Stroke | Not applicable | Not yet recruiting | Purdue University | 45 | 2025-10-01 | 2025-09-30 |
| Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women Dried plums - T Cell Response to Dried Plum, Vitamin D Influence on Immune Response | Not applicable | Recruiting | Indiana University | 30 | 2025-09-02 | 2025-10-29 |
| The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities Low Cysteine Diet, High Cysteine Diet - Colorectal Cancer | Not applicable | Recruiting | Purdue University | 40 | 2025-08-18 | 2026-05-14 |
| Scalable Intervention for Stress Management Resistance Breathing Device, Electronic Resistance Breathing Device - Stress, Diaphragmatic Breathing | Not applicable | Recruiting | Livotion, LLC | 60 | 2025-08-01 | 2025-08-17 |
| A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents Unsweetened Sparkling Water Replacement, Progressively Reduced Sugar Beverage Replacement, Plain Water Replacement - Obesity, Adolescent, Dietary Sugars | Not applicable | Recruiting | Nana Gletsu Miller | 63 | 2025-07-25 | 2026-08-06 |
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Obesity (31) · Appetitive Behavior (16) · Osteoporosis (11) · Feeding Behavior (10) · Hypertension (10) · Diabetes Mellitus, Type 2 (9) · Overweight (9) · Diabetes Mellitus (7) · Parkinson Disease (7) · Gastroparesis (6) · Cardiovascular Diseases (5) · Language Development Disorders (5) · Specific Language Disorder (5) · Anemia, Iron-Deficiency (4) · Body Weight (4)
Exercise (7) · Imatinib Mesylate (4) · maltodextrin (4) · Breakfast (3) · Inulin (3) · Progesterone (3) · Starch (3) · ibutilide (3) · Amino Acids (2) · Amiodarone (2) · Calcium (2) · Cholecalciferol (2) · Contraceptives, Oral, Combined (2) · Control Groups (2) · Desogestrel (2)
United States (229) · Kenya (8) · South Korea (4) · Canada (2) · Vietnam (2) · Bangladesh (1) · Ghana (1) · Niger (1) · Senegal (1) · Tanzania (1)
Richard D Mattes, PhD (17) · Wayne W Campbell, Ph.D. (11) · Berdine R Martin, PhD (7) · Connie M Weaver, PhD (7) · Thomas V Nowak, MD (7) · James E Tisdale, PharmD (6) · Bruce R Hamaker, PhD (5) · Dennis Savaiano, PhD (5) · Wayne Campbell, PhD (5) · Wayne W Campbell, PhD (5) · Connie Weaver, PhD (4) · Heather J Leidy, PhD (4) · Laurence B. Leonard, PhD (4) · Connie M Weaver, Ph.D. (3) · Heather Leidy, PhD (3)
PMID 26864362, PMID 34698750, PMID 37918675, PMID 15070956, PMID 15817862, PMID 17266087, PMID 17502632, PMID 17556706, PMID 18414066, PMID 19144727, PMID 19262464, PMID 19386746, PMID 19398687, PMID 19699916, PMID 20007307, PMID 20025041, PMID 20205166, PMID 20381077, PMID 20844256, PMID 20962148, PMID 21164556, PMID 21386044, PMID 21918216, PMID 22258267, PMID 22543981, PMID 22718030, PMID 22744746, PMID 22750015, PMID 23034474, PMID 23254903, PMID 23553157, PMID 24092833, PMID 24351876, PMID 24429540, PMID 24438910, PMID 24872223, PMID 24924750, PMID 24955495, PMID 25064672, PMID 25271941, PMID 25411033, PMID 25459460, PMID 26016861, PMID 26063693, PMID 26245807, PMID 26246322, PMID 26293568, PMID 26446485, PMID 26751193, PMID 26885880
R01DC014708 (5), 1OT2OD028183-01 (4), R01DK079913 (4), 1OT2OD023847-01 (2), R21HD110656 (2), R41AT012854 (2), 1UF1MH121949-01 (1), 2023 (1), 4UF1MH121949 (1), 5UG1DA049444 (1), F31DC019281 (1), OT2OD023847 (1), OT2OD030043 (1), OT2OD035404 (1), P30DK097512 (1)