53 completed, 11 unknown, 10 terminated, 5 recruiting. 36 Phase 2, 18 Phase 1, 13 Phase 3, 11 Not applicable.
Follow Testicular Germ Cell Tumor: new trials by email Literature Review of Testicular Germ Cell Tumor trials Research Report on Testicular Germ Cell Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care ICG-Guided Retroperitoneal Sentinel Lymph Node Biopsy, Radical Inguinal Orchiectomy - Testicular Cancer, Testicular Germ Cell Tumor | Not applicable | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 171 | 2027-01-01 | 2026-07-13 |
| Effect of Hypnosis in the Management of Anxiety and Chemo-induced Symptoms in Adolescents and Young Adults With Sarcoma or Germ Cell Tumor and in Young Women With Breast Cancer HYPNOSIS - Sarcoma, Germ Cell Tumor of Testis | Not applicable | Recruiting | Institut Bergonié | 70 | 2026-09-15 | 2026-09-22 |
| Sentinel Node Identification Using Gamma and Near-Infrared Imaging in TesticulAr MaLignancies Standard treatment: orchiectomy followed by drug therapy and, if necessary, retroperitoneal lymphadenectomy, sentinel lymph node mapping using technetium-99m (Tc-99m) and indocyanine green (ICG) with subsequent orchiectomy - Germ Cell Tumor of Testis | Recruiting | N.N. Petrov National Medical Research Center of Oncology | 60 | 2026-04-01 | 2026-08-27 | |
| A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm CLDN6 CAR-T, CLDN6 RNA-LPX - Testicular Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Withdrawn | BioNTech SE | 2025-07-01 | 2025-07-02 | |
| Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors XmAb541 - Ovarian Cancer, Endometrial Cancer | Phase 1 | Recruiting | Xencor, Inc. | 282 | 2024-04-04 | 2026-10-09 |
| Sentinel Lymph Node Biopsy in Stage AI-IIA Germ Cell Tumors Orchofuniculectomy with simultaneous laparoscopic biopsy of the sentinel lymph node using indocyanine green dye with/without methylene blue dye., Radiopharmaceutical administration (Technetium/methylene blue) - Testicular Germ Cell Tumor | Not applicable | Unknown | N.N. Petrov National Medical Research Center of Oncology | 44 | 2023-11-08 | 2024-01-03 |
| Follow-up After Surgery for Testicular Cancer Testicular Cancer, Testicular Germ Cell Tumor | Recruiting | Erasmus Medical Center | 145 | 2022-11-30 | 2023-02-23 | |
| A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors HFB200301, Tislelizumab - Gastric Cancer, Renal Cell Carcinoma | Phase 1 | Active not recruiting | HiFiBiO Therapeutics | 72 | 2022-03-10 | 2025-11-21 |
| Milademetan in Advanced/Metastatic Solid Tumors RAIN-32 - Solid Tumors, Head and Neck Carcinoma | Phase 2 | Terminated | Rain Oncology Inc | 40 | 2021-11-01 | 2024-10-17 |
| A Prospective Study to Evaluate miRNA371 and Outcomes in Patients With Newly Diagnosed Germ Cell Tumors Testicular Germ Cell Tumor | Recruiting | Fondazione del Piemonte per l'Oncologia | 100 | 2021-07-01 | 2026-03-05 | |
| Exercise in Testicular Germ Cell Cancer Survivors aerobic-strength exercise intervention (6-months) - Testicular Germ Cell Tumor | Not applicable | Unknown | Slovak Academy of Sciences | 60 | 2020-01-15 | 2023-12-05 |
| Exploratory Study of Molecular Characterization in Patients With Metastatic Germ Cell Tumours Refractory/Resistant to Platinum Treatment Testicular Germ Cell Tumor | Unknown | Royal Marsden NHS Foundation Trust | 18 | 2019-08-01 | 2019-06-10 | |
| Sentinel Lymph Node Procedure in Testicular Germ Cell Tumour sentinel node procedure - Testicular Germ Cell Tumor | Unknown | The Netherlands Cancer Institute | 76 | 2018-09-01 | 2018-08-22 | |
| Role of Axumin PET Scan in Germ Cell Tumor Axumin PET scan - Testis Cancer, Germ Cell Tumor | Completed | University of Texas Southwestern Medical Center | 10 | 2018-03-01 | 2025-08-11 | |
| Study of Cisplatin-Induced Peripheral Neuropathy in Patients With Germ Cell Tumor EORTC QLQ-CIPN20 - Testicular Germ Cell Tumor | Completed | Costantine Albany | 54 | 2015-07-01 | 2020-09-22 | |
| Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors Guadecitabine (SGI-110) - Germ Cell Tumor, Testis Cancer | Phase 1 | Completed | Nasser Hanna | 14 | 2015-04-27 | 2020-09-23 |
| A Case-control Study to Assess the Association Between Environmental, Domestic and Occupational Exposures and the Risk of Testicular Germ Cell Tumor Phone interview and blood test - Testicular Germ Cell Tumor | Completed | Centre Leon Berard | 1367 | 2015-01-01 | 2018-05-11 | |
| Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression DNA methylation analysis, RNA analysis, mutation analysis - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Completed | Children's Oncology Group | 90 | 2011-10-01 | 2016-05-18 | |
| High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy filgrastim, pegfilgrastim, carboplatin - Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor | Phase 2 | Unknown | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 47 | 2010-10-01 | 2013-08-12 |
| Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome Lactobacillus rhamnosus GG - Breast Cancer, Chronic Myeloproliferative Disorders | Not applicable | Terminated | Rutgers, The State University of New Jersey | 30 | 2010-03-01 | 2017-02-03 |
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PMID 11919245, PMID 12525530, PMID 15999102, PMID 16039331, PMID 16148284, PMID 16688776, PMID 17194908, PMID 17235042, PMID 17290059, PMID 17416851, PMID 17634488, PMID 19547919, PMID 20194867, PMID 21059637, PMID 21282539, PMID 25001888, PMID 25456363, PMID 32500206, PMID 35298280, PMID 37230752, PMID 37589506, PMID 39167741, PMID 9849694
P30CA008748 (3), P30CA068485 (3), P30CA033572 (2), P30CA043703 (2), P30CA069533 (2), U10CA021115 (2), 2005 (1), P30CA006516 (1), P30CA022453 (1), P30CA072720 (1), R21CA094523 (1), U10CA031946 (1)