2 completed, 2 recruiting, 2 terminated, 1 unknown. 8 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 2, Recruiting 2, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 1, Recruiting 1, Terminated 1, Unknown 1 |
Follow Cartilage Diseases: new trials by email Literature Review of Cartilage Diseases trials Research Report on Cartilage Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pragmatic, Open-Label Study to Pilot Evaluation for Clinical Trials in Relapsing Polychondritis Methotrexate (MTX), Azathioprine (AZA), Adalimumab - Relapsing Polychondritis | Phase 2 | Recruiting | University of Pennsylvania | 20 | 2025-11-11 | 2026-09-02 |
| Efficacy, Safety and Immunological Evaluation of Upadacitinib for Relapsing Polychondritis Upadacitinib, corticosteroids and immunosuppressants - Relapsing Polychondritis | Phase 1 / Phase 2 | Recruiting | Peking University People's Hospital | 30 | 2024-11-15 | 2025-03-12 |
| Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis Rituximab, Infliximab, Tocilizumab - Giant Cell Arteritis, Takayasu Arteritis | Phase 2 | Terminated | Cambridge University Hospitals NHS Foundation Trust | 22 | 2021-07-14 | 2025-06-17 |
| Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia Famotidine, Speech Language Therapy - Laryngomalacia, Gastro Esophageal Reflux | Phase 1 / Phase 2 | Terminated | Reema Padia | 65 | 2020-11-18 | 2025-07-20 |
| Low-dose Recombinant Human IL-2 for the Treatment of Relapsing Polychondritis Interleukin-2 - Relapsing Polychondritis | Phase 2 | Completed | Peking University People's Hospital | 10 | 2019-11-01 | 2024-02-26 |
| Safety and Efficacy Study of Cells Sheet-Autologous Chondrocyte Implantation to Treat Articular Cartilage Defects CS-ACI - Osteochondritis, Osteochondritis Dissecans | Phase 1 / Phase 2 | Unknown | Yan Jin | 10 | 2012-04-01 | 2012-10-01 |
| Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis Autologous MSC knee implantation - Osteoarthritis, Knee, Knee Injuries | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 15 | 2010-10-01 | 2015-12-11 |
| Tocilizumab for Relapsing Polychondritis Tocilizumab - Relapsing Polychondritis | Phase 2 | Withdrawn | McMaster Children's Hospital | 2010-05-01 | 2014-05-13 |
Polychondritis, Relapsing (5) · Joint Diseases (2) · Vasculitis (2) · Cogan Syndrome (1) · Communication Disorders (1) · Cryoglobulinemia, Familial Mixed (1) · Gastroesophageal Reflux (1) · Giant Cell Arteritis (1) · IgA Vasculitis (1) · Inflammation (1) · Knee Injuries (1) · Laryngomalacia (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1)
Connective Tissue Diseases (8) · Musculoskeletal Diseases (8) · Skin and Connective Tissue Diseases (8) · Pathological Conditions, Signs and Symptoms (3) · Cardiovascular Diseases (2) · Nervous System Diseases (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Vascular Diseases (2) · Aortic Arch Syndromes (1) · Aortic Diseases (1) · Arteritis (1) · Arthritis (1) · Autoimmune Diseases (1)
tocilizumab (3) · Infliximab (2) · Adalimumab (1) · Adrenal Cortex Hormones (1) · Azathioprine (1) · Famotidine (1) · Immunosuppressive Agents (1) · Interleukin-2 (1) · Methotrexate (1) · Rituximab (1) · Speech Therapy (1) · aldesleukin (1) · upadacitinib (1)
Peking University People's Hospital (2) · Banc de Sang i Teixits (1) · Cambridge University Hospitals NHS Foundation Trust (1) · McMaster Children's Hospital (1) · Reema Padia (1) · University of Pennsylvania (1) · Yan Jin (1)
China (3) · United States (2) · Canada (1) · Spain (1) · United Kingdom (1)
David Jayne (1) · Jin Yan, Ph.D (1) · Li Zhanguo (1) · Reema Padia, MD (1) · Robert Soler, MD (1) · Shubhasree Banerjee, MD (1) · Zhanguo Li (1)