10 completed. 10 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 10 |
| Phase 2 | 5 | Completed 5 |
Follow Cardiomyopathy: new trials by email Literature Review of Cardiomyopathy trials Research Report on Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Bioequivalence Study of Two Formulations of HRS-1893 Tablets in Healthy Participants Test formulation of HRS-1893 tablet, Reference formulation of HRS-1893 tablet - Cardiomyopathy | Phase 1 | Completed | Shandong Suncadia Medicine Co., Ltd. | 58 | 2026-04-14 | 2026-09-21 |
| A Phase I Trial on the Relative Bioavailability and Food Effect of HRS-1893 Tablets in Healthy Subjects HRS-1893 tablet A, HRS-1893 tablet B - Cardiomyopathy | Phase 1 | Completed | Shandong Suncadia Medicine Co., Ltd. | 38 | 2025-12-11 | 2026-04-02 |
| Nebulized Inhaled Milrinone in a Hospitalized Advanced Heart Failure Population Inhaled nebulized milrinone - Heart Failure, Cardiomyopathy | Phase 1 | Completed | University of Kansas Medical Center | 10 | 2020-06-15 | 2024-09-19 |
| Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia stereotactic body radiotherapy (SBRT) - Ventricular Tachycardia, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 19 | 2016-07-01 | 2024-08-21 |
| Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines Laboratory Biomarker Analysis, Standard of Care, Mesenchymal Stem Cell Transplantation - Cardiomyopathy, Heart Failure | Phase 1 | Completed | M.D. Anderson Cancer Center | 7 | 2016-01-11 | 2022-05-17 |
| AiDing Diuresis wIth Tolvaptan (ADD-IT) Tolvaptan 30 mg + IV Diuretics, Metolazone 5 mg + IV Diuretics, 2.5 times the Diuretics Dose - Cardiomyopathy, Congestive Heart Failure | Phase 1 | Completed | Emory University | 14 | 2016-01-01 | 2019-03-27 |
| Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) Tadalafil, Placebo - Cardiomyopathy, Renal Impairment | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2014-03-01 | 2020-10-28 |
| Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) Tadalafil, Placebo - Cardiomyopathy, Renal Impairment | Phase 1 / Phase 2 | Completed | Mayo Clinic | 20 | 2014-01-09 | 2021-06-11 |
| Intracoronary Transplantation of Bone Marrow Derived Mononuclear Cells in Pediatric Cardiomyopathy Mono Nuclear Cell (MNC) transplantation - Cardiomyopathy | Phase 1 / Phase 2 | Completed | Nasser Aghdami MD., PhD | 30 | 2013-06-01 | 2017-04-27 |
| Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure B-type Natriuretic Peptide (BNP), Placebo - Congestive Heart Failure, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Horng Chen | 45 | 2000-01-01 | 2012-12-20 |
Cardiomyopathies (10) · Heart Failure (4) · Renal Insufficiency (2) · Respiratory Aspiration (1) · Tachycardia, Ventricular (1) · Ventricular Premature Complexes (1)
Cardiovascular Diseases (10) · Heart Diseases (10) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Urogenital Diseases (2) · Urologic Diseases (2) · Arrhythmias, Cardiac (1) · Cardiac Complexes, Premature (1) · Cardiac Conduction System Disease (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1)
Tadalafil (2) · Diuretics (1) · Furosemide (1) · Mesenchymal Stem Cell Transplantation (1) · Metolazone (1) · Natriuretic Peptide, Brain (1) · Radiosurgery (1) · Standard of Care (1) · Tablets (1) · Tolvaptan (1) · Transplantation (1)
Mayo Clinic (2) · Shandong Suncadia Medicine Co., Ltd. (2) · Emory University (1) · Horng Chen (1) · M.D. Anderson Cancer Center (1) · Nasser Aghdami MD., PhD (1) · University of Kansas Medical Center (1) · Washington University School of Medicine (1)
United States (7) · China (2) · Iran (1)
Horng H Chen, MD (2) · Amanda Olson (1) · Divya Gupta, MD (1) · Hamid Gourabi, PhD (1) · Horng H. Chen, M.D. (1) · Koorosh Vahidshahi, MD (1) · Mohammad Mahdavi, MD (1) · Nasser Aghdami, MD,PhD (1) · Phillip Cuculich, MD (1) · Zachary L Cox, PharmD (1) · Zubair Shah, MD (1)
PMID 23122795, PMID 30586734, PMID 35001638, PMID 37295665, PMID 37871843
P01HL076611 (1), R01HL036634 (1), R01HL084155 (1), UL1RR024150 (1)