8 completed, 6 unknown, 1 active not recruiting, 1 not yet recruiting. 8 Phase 1, 6 Phase 2, 3 Not applicable, 2 Phase 3, 1 Early Phase 1.
Follow Mesenchymal Stem Cell Transplantation: new trials by email Literature Review of Mesenchymal Stem Cell Transplantation trials Research Report on Mesenchymal Stem Cell Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Bone Marrow Stem Cells (MesenCell) for the Treatment of Patients With Chronic Graft-versus-host Disease Mesenchymal Stem Cell Infusion - Graft vs Host Disease, Mesenchymal Stem Cell Transplantation | Phase 1 | Not yet recruiting | Pontifícia Universidade Católica do Paraná | 20 | 2026-10-01 | 2026-09-17 |
| Retrospective Results of Micronized Adipose Tissue in Patients With Interstitial Cystitis Mesenchymal Stem Cell Transplantation - Interstitial Cystitis/Painful Bladder Syndrome | Completed | University of Roma La Sapienza | 20 | 2024-04-04 | 2025-08-05 | |
| Autologous Bone Marrow Stem Cell Transplantation in Patients With Subacute Spinal Cord Injury Mesenchymal stem cell transplantation, Placebo - Spinal Cord Injuries | Phase 2 | Unknown | SENAI CIMATEC | 40 | 2023-04-01 | 2023-01-12 |
| Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines Best Practice, Laboratory Biomarker Analysis, Mesenchymal Stem Cell Transplantation - Cardiomyopathy, Heart Failure | Phase 1 | Suspended | M.D. Anderson Cancer Center | 72 | 2020-07-18 | 2026-11-02 |
| Comparative Study of Strategies for Management of Duchenne Myopathy (DM) Sildenafil (Phosphodiesterase inhibitors), Prednisolone (Steroids), Mesenchymal stem cell transplantation - Myopathy | Phase 4 | Unknown | Assiut University | 45 | 2018-09-01 | 2018-08-16 |
| Mesenchymal Stem Cell Transplantation for Acute-on-chronic Liver Failure mesenchymal stem cell transplantation or placebo infusion via peripheral vein - Acute-On-Chronic Liver Failure | Not applicable | Unknown | Xijing Hospital of Digestive Diseases | 200 | 2017-12-10 | 2018-09-12 |
| Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis mesenchymal stem cell transplantation or placebo infusion via peripheral vein - Primary Biliary Cirrhosis | Not applicable | Unknown | Xijing Hospital of Digestive Diseases | 140 | 2017-11-08 | 2018-09-12 |
| Stem Cell Transplantation in Cirrhotic Patients Mesenchymal stem cell transplantation - Liver Cirrhosis | Phase 1 / Phase 2 | Unknown | Assiut University | 40 | 2016-10-01 | 2016-10-25 |
| Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines Laboratory Biomarker Analysis, Standard of Care, Mesenchymal Stem Cell Transplantation - Cardiomyopathy, Heart Failure | Phase 1 | Completed | M.D. Anderson Cancer Center | 7 | 2016-01-11 | 2022-05-17 |
| Intra-Osseous Co-Transplant of UCB and hMSC cyclophosphamide, fludarabine phosphate, total-body irradiation - Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 6 | 2015-07-22 | 2020-12-04 |
| Evaluation of Autologous Mesenchymal Stem Cell Transplantation in Chronic Spinal Cord Injury: a Pilot Study Mesenchymal stem cell transplantation - Spinal Cord Injury | Not applicable | Completed | Hospital Sao Rafael | 5 | 2015-01-01 | 2017-04-26 |
| MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer Laboratory Biomarker Analysis, Mesenchymal Stem Cell Transplantation, Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter - Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | Mayo Clinic | 34 | 2014-04-25 | 2026-08-24 |
| Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease mesenchymal cell transplantation, mesenchymal cell and fibroblast injection - Crohn's Disease | Phase 1 | Unknown | Royan Institute | 10 | 2013-02-01 | 2017-04-27 |
| Bone Marrow Derived Stem Cell Transplantation in T2DM mesenchymal stem cell transplantation, control, MNC's TRANSPLANTATION - Type 2 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2012-12-01 | 2015-10-27 |
| Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs Cyclophosphamide, Fludarabine, Anti-thymocyte globulin - Epidermolysis Bullosa | Phase 1 / Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 32 | 2010-01-01 | 2024-04-03 |
| Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis mesenchymal cell transplantation, placebo - Rheumatoid Arthritis | Phase 2 / Phase 3 | Completed | Royan Institute | 60 | 2009-10-01 | 2013-06-10 |
| Treatment of Severe Osteogenesis Imperfecta by Allogeneic Bone Marrow Transplantation Bone Marrow Cell Transplantation, Irradiation, Total Body, Cyclophosphamide - Osteogenesis Imperfecta | Phase 1 | Completed | St. Jude Children's Research Hospital | 9 | 1995-11-01 | 2008-06-25 |
Cardiomyopathies (2) · Heart Failure (2) · Spinal Cord Injuries (2) · Acute-On-Chronic Liver Failure (1) · Arthritis, Rheumatoid (1) · Brenner Tumor (1) · Crohn Disease (1) · Cystitis, Interstitial (1) · Diabetes Mellitus, Type 2 (1) · Epidermolysis Bullosa (1) · Fallopian Tube Neoplasms (1) · Fistula (1) · Graft vs Host Disease (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1)
Assiut University (2) · M.D. Anderson Cancer Center (2) · Royan Institute (2) · Xijing Hospital of Digestive Diseases (2) · Case Comprehensive Cancer Center (1) · Hospital Sao Rafael (1) · Masonic Cancer Center, University of Minnesota (1) · Mayo Clinic (1) · Pontifícia Universidade Católica do Paraná (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · SENAI CIMATEC (1) · St. Jude Children's Research Hospital (1) · University of Roma La Sapienza (1)
United States (6) · Brazil (3) · China (2) · Iran (2) · India (1) · Italy (1)
Hamid Gourabi, PhD (2) · Nasser Aghdami, MD,PhD (2) · A Bhansali (1) · Alexandre S Carvalho-da-Silva, Student (1) · Amanda Olson (1) · Augusto Mota, PhD (1) · Bruno SF Souza, MD, Msc (1) · Carmen L K Rebelatto, PhD (1) · Cristiane F Villarreal, PhD (1) · Emad EL Daly, Professor (1) · Evanthia Galanis, MD (1) · Jakub Tolar, MD, PhD (1) · Kimberly Kasow, DO (1)
PMID 28690682, PMID 29428486, PMID 32864818, PMID 34953040, PMID 35410640
P30CA043703 (1), P50CA136393 (1), R01CA136547 (1), R01CA200507 (1)