5 completed, 2 active not recruiting, 1 recruiting, 1 suspended. 2 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Recruiting 1, Suspended 1 |
| Phase 2 | 1 | Terminated 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Cardiac Fibrosis: new trials by email Literature Review of Cardiac Fibrosis trials Research Report on Cardiac Fibrosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Genetic Polymorphism on the Clinical Outcome to SGLT2 Inhibitors in Heart Failure Patients SGLT2 inhibitor (Dapagliflozin 10mg) - Heart Failure - NYHA II - IV, Cardiac Fibrosis | Active not recruiting | Ain Shams University | 200 | 2023-11-22 | 2025-03-30 | |
| The Effects of Inositol on Glucose Metabolism in Patients With Metabolic Syndrome at Risk of Cardiac Fibrosis Inositol and alpha-lactalbumin - Metabolic Syndrome, Cardiac Fibrosis | Not applicable | Suspended | Lo.Li.Pharma s.r.l | 30 | 2022-12-23 | 2025-12-30 |
| Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency Metformin Extended Release Oral Tablet - Plasminogen Activator Inhibitor-1 Deficiency, Cardiac Fibrosis | Phase 4 | Active not recruiting | Indiana Hemophilia &Thrombosis Center, Inc. | 15 | 2022-10-10 | 2024-11-06 |
| Immune Correlates of Cardiac Structure and Function Cardiac MRI - Perinatal HIV Infection, Cardiac Fibrosis | Completed | Duke University | 40 | 2022-05-09 | 2024-03-21 | |
| Cardiovascular Fibrosis in Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis, Cardiac Fibrosis | Completed | San Gerardo Hospital | 100 | 2019-10-21 | 2022-10-26 | |
| Early MRI Detection of Myocardial Deterioration as a Preventive, Disease Staging, and Prognostic Biomarker in Insulin Resistance Cardiomyopathies, Insulin Resistance | Completed | Stanford University | 39 | 2015-01-15 | 2023-03-24 | |
| Characterization of Heart Failure With Preserved Ejection Fraction cMR, biomarker - Heart Failure, Preserved Ejection Fraction, Cardiac Fibrosis | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 500 | 2014-12-04 | 2024-02-05 |
| Pilot Study of Cardiac MR in Patients With Muscular Dystrophy Muscular Dystrophies, Cardiac Fibrosis | Completed | Children's National Research Institute | 60 | 2014-01-01 | 2024-12-11 | |
| Effects of Pycnogenol on Cardiac Fibrosis and Diastolic Dysfunction in Aged Hypertensive Subjects Pycnogenol, Placebo - Cardiac Fibrosis, Diastolic Dysfunction | Phase 2 | Terminated | University of Arizona | 9 | 2009-07-01 | 2013-12-17 |
| Circulating P3NP and Cardiovascular Events in Hemodialysis Patients Cardiovascular Events, Cardiac Fibrosis | Completed | Toujinkai Hospital | 244 | 2005-01-01 | 2018-01-08 |
Cardiomyopathies (1) · Diabetes Mellitus (1) · Genetic Diseases, Inborn (1) · Heart Failure, Diastolic (1) · Hypertension (1) · Idiopathic Pulmonary Fibrosis (1) · Insulin Resistance (1) · Metabolic Syndrome (1) · Muscular Dystrophies (1) · Musculoskeletal Diseases (1) · Plasminogen Activator Inhibitor-1 Deficiency (1)
Cardiovascular Diseases (3) · Glucose Metabolism Disorders (2) · Heart Diseases (2) · Hyperinsulinism (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Endocrine System Diseases (1) · Heart Failure (1) · Insulin Resistance (1) · Lung Diseases (1) · Lung Diseases, Interstitial (1) · Muscular Diseases (1) · Muscular Disorders, Atrophic (1) · Nervous System Diseases (1)
Biomarkers (1) · Inositol (1) · Lactalbumin (1) · Metformin (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · dapagliflozin (1) · pycnogenols (1)
Ain Shams University (1) · Children's National Research Institute (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Duke University (1) · Indiana Hemophilia &Thrombosis Center, Inc. (1) · Lo.Li.Pharma s.r.l (1) · San Gerardo Hospital (1) · Stanford University (1) · Toujinkai Hospital (1) · University of Arizona (1)
United States (5) · Italy (2) · Belgium (1) · Egypt (1) · Japan (1)
Abha Khandelwal, MD (1) · Amy D Shapiro, MD (1) · Anne Catherine Pouleur (1) · Bassem Zarif, MD (1) · Christopher Spurney, MD (1) · Claudio Ferri, MD (1) · Davide Grassi, MD (1) · Gerald Bloomfield, MD (1) · Magdalena Lewandowska, MD (1) · Masato Nishimura, MD (1) · Paola Faverio, MD (1) · Rajesh Dash, MD, PhD (1) · Ronald R Watson, PhD (1) · Sweta Gupta, MD (1)
PMID 30086783, PMID 39077419, PMID 40121452, PMID 41495328
R56HL152803 (1)