10 completed, 2 terminated, 1 unknown, 1 withdrawn. 6 Phase 1, 4 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 6 |
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
Follow Carcinoma of the Appendix: new trials by email Literature Review of Carcinoma of the Appendix trials Research Report on Carcinoma of the Appendix
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs Stage III Breast Cancer, Stage IV Breast Cancer | Withdrawn | Travera Inc | 2024-11-01 | 2024-11-25 | ||
| Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx) Pleural Effusion, Malignant, Ascites, Malignant | Completed | Travera Inc | 72 | 2022-07-15 | 2026-04-13 | |
| Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires - Advanced Malignant Mesothelioma, Carcinoma of the Appendix | Not applicable | Completed | Wake Forest University Health Sciences | 10 | 2010-05-01 | 2018-07-03 |
| Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer palonosetron hydrochloride, placebo - Anal Cancer, Carcinoma of the Appendix | Phase 2 | Terminated | Alliance for Clinical Trials in Oncology | 7 | 2009-09-01 | 2017-11-24 |
| Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix mitomycin C, oxaliplatin, therapeutic conventional surgery - Carcinoma of the Appendix, Primary Peritoneal Cavity Cancer | Phase 2 | Completed | Wake Forest University Health Sciences | 136 | 2009-05-01 | 2018-07-03 |
| Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer fluorouracil, irinotecan hydrochloride, leucovorin calcium - Anal Cancer, Carcinoma of the Appendix | Phase 1 | Completed | Mayo Clinic | 7 | 2008-06-01 | 2017-05-25 |
| Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer oxaliplatin - Carcinoma of the Appendix, Colorectal Cancer | Phase 1 | Completed | Wake Forest University Health Sciences | 16 | 2007-03-01 | 2018-08-09 |
| Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer cetuximab, erlotinib hydrochloride, laboratory biomarker analysis - Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | Phase 1 | Completed | National Cancer Institute (NCI) | 43 | 2007-01-01 | 2015-09-30 |
| EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer EF5, motexafin lutetium, pharmacological study - Advanced Adult Primary Liver Cancer, Carcinoma of the Appendix | Not applicable | Terminated | National Cancer Institute (NCI) | 30 | 2004-05-01 | 2013-01-16 |
| Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer thalidomide, surgery - Carcinoma of the Appendix, Colorectal Cancer | Phase 2 | Completed | Wake Forest University Health Sciences | 29 | 2002-10-01 | 2018-08-23 |
| 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) 7-hydroxystaurosporine, irinotecan hydrochloride, diagnostic laboratory biomarker analysis - Advanced Adult Primary Liver Cancer, Carcinoma of the Appendix | Phase 1 | Completed | National Cancer Institute (NCI) | 41 | 2001-12-01 | 2013-09-30 |
| Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu recombinant interleukin-12, ABI-007/carboplatin/trastuzumab - Advanced Adult Primary Liver Cancer, Anaplastic Thyroid Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 15 | 1999-08-01 | 2013-02-28 |
| Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer capecitabine, oxaliplatin - Carcinoma of the Appendix, Colorectal Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 1999-07-01 | 2015-04-29 | |
| Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer chemotherapy, fluorouracil, leucovorin calcium - Carcinoma of the Appendix, Colorectal Cancer | Phase 2 | Unknown | Gustave Roussy, Cancer Campus, Grand Paris | 1996-01-01 | 2011-04-26 |
Appendiceal Neoplasms (14) · Colonic Neoplasms (12) · Rectal Neoplasms (10) · Carcinoma, Hepatocellular (8) · Pancreatic Neoplasms (8) · Anus Neoplasms (7) · Stomach Neoplasms (7) · Bile Duct Neoplasms (6) · Carcinoma, Non-Small-Cell Lung (6) · Colorectal Neoplasms (6) · Esophageal Neoplasms (6) · Gallbladder Neoplasms (6) · Gastrointestinal Stromal Tumors (5) · Breast Neoplasms (4) · Carcinoma, Ovarian Epithelial (4)
Cecal Diseases (14) · Cecal Neoplasms (14) · Digestive System Diseases (14) · Digestive System Neoplasms (14) · Gastrointestinal Diseases (14) · Gastrointestinal Neoplasms (14) · Intestinal Diseases (14) · Intestinal Neoplasms (14) · Neoplasms (14) · Neoplasms by Site (14) · Colonic Diseases (12) · Rectal Diseases (12) · Adenocarcinoma (9) · Endocrine Gland Neoplasms (9) · Endocrine System Diseases (9)
Oxaliplatin (3) · Fluorouracil (2) · Irinotecan (2) · Leucovorin (2) · Mitomycin (2) · 7-hydroxystaurosporine (1) · Capecitabine (1) · Cetuximab (1) · Drug Therapy (1) · Erlotinib Hydrochloride (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Interleukin-12 (1) · Interleukin-12 Subunit p35 (1) · Palonosetron (1) · Pharmacogenomic Testing (1)
National Cancer Institute (NCI) (5) · Wake Forest University Health Sciences (4) · Travera Inc (2) · Alliance for Clinical Trials in Oncology (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Mayo Clinic (1)
United States (12) · France (1)
Dominique Elias, MD (1) · Edward Levine (1) · Eva Szabo, MD (1) · John H. Stewart, MD (1) · Laura Goff (1) · Mark Stevens, Ph.D. (1) · Mark Stevens, Phd (1) · Michele Yvette Halyard, MD (1) · Paula Fracasso (1) · Perry Shen, MD (1) · Richard McQuellon (1) · Rob Kimmerling, Phd (1) · Robert Kimmerling, Ph.D. (1) · Robert McWilliams, MD (1) · Stephen Michael Hahn (1)
PMID 11919233, PMID 14981738, PMID 18493824
P01CA087971 (1), P30CA012197 (1), P30CA015083 (1), P30CA044579 (1), P30CA068485 (1), U01CA076576 (1)