6 terminated, 4 completed, 2 active not recruiting, 2 unknown. 15 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Terminated 6, Completed 4, Active not recruiting 2, Unknown 2, Not yet recruiting 1 |
| Phase 2 | 7 | Terminated 4, Unknown 2, Completed 1 |
Follow Cancer of Pancreas: new trials by email Literature Review of Cancer of Pancreas trials Research Report on Cancer of Pancreas
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors STI-1386 - Cancer, Cancer of Pancreas | Phase 1 | Not yet recruiting | Sorrento Therapeutics, Inc. | 36 | 2023-08-01 | 2023-04-12 |
| A Study of Bi-Ligand-Drug Conjugate CBP-1019 in Patients With Advanced Solid Tumors CBP-1019 - Cancer, Breast, Cancer, Lung | Phase 1 / Phase 2 | Unknown | Coherent Biopharma (Hefei) Co., Ltd. | 260 | 2023-03-14 | 2024-08-26 |
| A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation HBI-2438 - Lung Cancer, Non Small Cell Lung Cancer | Phase 1 | Active not recruiting | HUYABIO International, LLC. | 44 | 2022-08-01 | 2025-09-24 |
| NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors NUV-868, Olaparib, Enzalutamide - Advanced Solid Tumor, Ovarian Cancer | Phase 1 | Terminated | Nuvation Bio Inc. | 82 | 2022-03-29 | 2025-11-06 |
| A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations HBI-2376 - Non Small Cell Lung Cancer, Colorectal Cancer | Phase 1 | Active not recruiting | HUYABIO International, LLC. | 42 | 2021-12-13 | 2025-09-24 |
| A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies Cannabidiol, Bortezomib, Leucovorin - Cancer of Pancreas, Cancer of Liver | Phase 1 / Phase 2 | Unknown | Leaf Vertical Inc. | 160 | 2019-01-15 | 2018-07-31 |
| Clinical Trial of Chemotherapy and Bemcentinib for Metastatic Pancreatic Cancer Bemcentinib, Nab-paclitaxel, Gemcitabine - Cancer of Pancreas | Phase 1 / Phase 2 | Terminated | University of Texas Southwestern Medical Center | 9 | 2019-01-03 | 2023-11-09 |
| M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the Pancreas M7824, Gemcitabine - Cancer of Pancreas, Pancreas Cancer | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 7 | 2018-05-17 | 2021-06-16 |
| Study of Nintedanib and Chemotherapy for Advanced Pancreatic Cancer Nintedanib - Cancer of Pancreas | Phase 1 / Phase 2 | Terminated | University of Texas Southwestern Medical Center | 14 | 2017-09-07 | 2024-06-03 |
| Epidural Analgesia Use in Pancreatic Resections Bupivacaine - Cancer of Pancreas, Cancer of the Pancreas | Phase 1 | Completed | Washington University School of Medicine | 23 | 2016-06-07 | 2020-03-12 |
| BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer BVD-523, Nab-paclitaxel, Gemcitabine - Pancreatic Cancer, Cancer of Pancreas | Phase 1 | Terminated | Washington University School of Medicine | 18 | 2016-06-06 | 2021-04-21 |
| Tosedostat With Capecitabine in Patients With Metastatic Pancreatic Adenocarcinoma Tosedostat, Capecitabine, Fresh tissue biopsy - Pancreatic Cancer, Cancer of Pancreas | Phase 1 / Phase 2 | Terminated | Washington University School of Medicine | 16 | 2015-08-31 | 2019-08-28 |
| Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer Durvalumab, Tremelimumab, Sterostatic body radiation therapy (SBRT) - Pancreatic Neoplasms, Pancreatic Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 65 | 2015-03-25 | 2021-04-20 |
| Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer Modified FOLFIRINOX, Stereotactic Body Radiotherapy (SBRT) - Cancer of Pancreas, Cancer of the Pancreas | Phase 1 | Completed | Emory University | 13 | 2011-11-01 | 2016-03-22 |
| Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer) FOLFOX6, EGFRBi armed ATC Infusions - Colorectal Cancer, Cancer of Pancreas | Phase 1 | Completed | Barbara Ann Karmanos Cancer Institute | 15 | 2011-08-17 | 2023-05-06 |
Pancreatic Neoplasms (15) · Colonic Neoplasms (5) · Colorectal Neoplasms (3) · Neoplasms (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Lung Neoplasms (2) · Esophageal Neoplasms (1) · Gallbladder Neoplasms (1) · Glioblastoma (1) · Liver Neoplasms (1) · Multiple Myeloma (1) · Ovarian Neoplasms (1) · Prostatic Neoplasms (1) · Prostatic Neoplasms, Castration-Resistant (1)
Digestive System Diseases (15) · Digestive System Neoplasms (15) · Endocrine Gland Neoplasms (15) · Endocrine System Diseases (15) · Neoplasms by Site (15) · Pancreatic Diseases (15) · Neoplasms (12) · Colonic Diseases (5) · Gastrointestinal Diseases (5) · Gastrointestinal Neoplasms (5) · Intestinal Diseases (5) · Intestinal Neoplasms (5) · Rectal Diseases (4) · Lung Diseases (3) · Respiratory Tract Diseases (3)
Gemcitabine (4) · 130-nm albumin-bound paclitaxel (2) · Albumin-Bound Paclitaxel (2) · Fluorouracil (2) · Leucovorin (2) · Oxaliplatin (2) · Bevacizumab (1) · Bortezomib (1) · Bupivacaine (1) · Cannabidiol (1) · Capecitabine (1) · Cisplatin (1) · Folfox protocol (1) · Injections (1) · Irinotecan (1)
Washington University School of Medicine (3) · HUYABIO International, LLC. (2) · National Cancer Institute (NCI) (2) · University of Texas Southwestern Medical Center (2) · Barbara Ann Karmanos Cancer Institute (1) · Coherent Biopharma (Hefei) Co., Ltd. (1) · Emory University (1) · Leaf Vertical Inc. (1) · Nuvation Bio Inc. (1) · Sorrento Therapeutics, Inc. (1)
United States (14) · Puerto Rico (2) · Australia (1) · China (1)
Alberto Bessudo, MD (1) · Andrea Wang-Gillam, M.D., Ph.D. (1) · Anthony Shields, M.D. PhD (1) · Kian-Huat Lim, M.D., Ph.D. (1) · Lin Shen, MD (1) · Michael Bottros, M.D. (1) · Mike Royal, MD (1) · Natalyn N. Hawk, MD, PhD (1) · Ravi Salgia, MD (1) · Salwan Al Mutar, MD (1) · Sarah F Katta, DO (1) · Syed Kazmi, MD (1) · Tim F Greten, M.D. (1) · Udo Rudloff, M.D. (1)
PMID 27475674, PMID 28939558, PMID 29374667, PMID 32939319, PMID 36427020
P50CA196510 (1)