16 completed, 9 terminated, 5 active not recruiting, 4 unknown. 12 Phase 2, 11 Not applicable, 9 Phase 1, 2 Phase 3.
Follow Bone Cancer: new trials by email Literature Review of Bone Cancer trials Research Report on Bone Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I/II Trial of Dinutuximab Beta in Combination With Irinotecan and Rapamycin in Pediatric, Adolescents and Adult Patients With Relapsed/Refractory Bone Tumors. Dinutuximab beta, Sirolimus and Irinotecan - Osteosarcomas, Bone Cancer | Phase 1 / Phase 2 | Not yet recruiting | University Hospital, Strasbourg, France | 89 | 2026-10-01 | 2026-10-01 |
| Medical Payment Case Management for Financial Toxicity in Patients With Primary Bone Tumors: A Randomized Controlled Trial Medical payment case management service - Bone Tumor, Bone Cancer | Not applicable | Recruiting | Shanghai 6th People's Hospital | 124 | 2026-09-19 | 2026-10-22 |
| Treatment of Truncated ALK-positive Bone Cancer Using Crizotinib (Xalkori) or Alectinib (Alecensa) Alectinib - Bone Cancer | Phase 1 / Phase 2 | Not yet recruiting | China Medical University Hospital | 10 | 2026-05-15 | 2026-05-11 |
| Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma intra-arterial cisplatin plus anti-angiogenesis inhibitor rh-endostatin (Endostar) - Osteosarcoma, Bone Cancer | Phase 1 / Phase 2 | Completed | Shanghai 6th People's Hospital | 10 | 2024-12-03 | 2025-12-29 |
| Enhanced Assistance During Radiotherapy for Unmet Essential Needs Standard assistance, Enhanced assistance - Bone Cancer, Brain Cancer | Not applicable | Completed | Washington University School of Medicine | 33 | 2024-10-04 | 2025-08-26 |
| Insights Into Participating in Studies for Bone Cancer Bone Cancer | Not yet recruiting | Power Life Sciences Inc. | 500 | 2024-10-01 | 2023-10-06 | |
| Proximal Femur Reconstruction Following Resection of Primary Bone Tumors: Analysis of the Clinical and Radiographic Results Analysis - Bone Tumor, Bone Cancer | Recruiting | Costantino Errani | 150 | 2024-04-29 | 2026-05-26 | |
| Pediatric Oncological Orthopaedic Reconstruction Analysis - Bone Tumor, Bone Cancer | Active not recruiting | Costantino Errani | 400 | 2023-12-01 | 2025-08-01 | |
| The Effects of Observer Presence and Type on Patients' Perception of Exercise After Bone Tumor Resection-A Qualitative Study Supervised Exercise by a physiotherapist via face to face, Supervised Exercise by a physiotherapist via video conference - Bone Cancer, Tumor | Not applicable | Unknown | Istanbul Medeniyet University | 30 | 2022-08-15 | 2022-05-31 |
| The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors Virtual group based physical activity (BurnAlong) and Social Media Discussion Board - Cancer, Cancer Metastatic | Not applicable | Completed | Cedars-Sinai Medical Center | 8 | 2022-07-25 | 2025-02-26 |
| A Dose Finding Study to Treat Bone Tumor(s) 153-Sm-DOTMP (Samarium-153-DOTMP) - Bone Cancer, Bone Tumor | Phase 1 | Terminated | QSAM Therapeutics, Inc. | 5 | 2022-04-05 | 2026-07-23 |
| Osteosarcoma Maintenance Therapy With OST31-164 OST31-164 - Bone Cancer | Phase 2 | Active not recruiting | Emerald Clinical Inc. | 39 | 2021-10-21 | 2025-01-22 |
| Functional Outcomes of Knee Protheses for Malignant Tumours of Bone MUTARS® modular reconstruction prostheses - Knee Disease, Bone Cancer | Not applicable | Completed | University Hospital, Lille | 9 | 2021-07-01 | 2026-04-21 |
| The Registry of Oncology Outcomes Associated With Testing and Treatment Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P) - Adenocarcinoma, Adenocystic Carcinoma | Completed | Taproot Health | 167 | 2021-05-05 | 2024-12-18 | |
| Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases External beam radiotherapy, MR-HIFU - Bone Metastases, Bone Neoplasm | Not applicable | Active not recruiting | UMC Utrecht | 216 | 2020-03-10 | 2026-03-05 |
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis combined radiotherapy and MR-HIFU - Bone Metastases, Bone Neoplasm | Phase 1 / Phase 2 | Completed | UMC Utrecht | 10 | 2019-04-11 | 2024-02-07 |
| 9-ING-41 in Patients With Advanced Cancers 9-ING-41, Gemcitabine - 21 day cycle, Doxorubicin. - Cancer, Pancreatic Cancer | Phase 2 | Active not recruiting | Actuate Therapeutics Inc. | 350 | 2019-01-04 | 2026-04-03 |
| Massive Implants the Next Generation custom made device - Bone Cancer, Bone Diseases | Not applicable | Unknown | Iva Hauptmannova | 30 | 2018-09-20 | 2022-06-07 |
| Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. 177Lu-3BP-227 (also called 177Lu-IPN01087) - Pancreatic Ductal Adenocarcinoma, Colorectal Cancer | Phase 1 | Terminated | Ipsen | 14 | 2018-05-03 | 2023-12-12 |
| MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases Thermal ablation of bone metastasis with MR-HIFU device Philips Sonalleve coupled with Philips Ingenia 3.0T, Varian Truebeam Radiotherapy System - Bone Metastases, Bone Neoplasm | Not applicable | Unknown | Turku University Hospital | 30 | 2017-05-15 | 2017-04-24 |
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Bone Neoplasms (40) · Neoplasms (13) · Lung Neoplasms (9) · Neoplasm Metastasis (9) · Breast Neoplasms (8) · Osteosarcoma (8) · Prostatic Neoplasms (7) · Colorectal Neoplasms (6) · Sarcoma (6) · Brain Neoplasms (5) · Pancreatic Neoplasms (5) · Skin Neoplasms (5) · Thyroid Neoplasms (5) · Carcinoma, Renal Cell (4) · Head and Neck Neoplasms (4)
Musculoskeletal Diseases (40) · Neoplasms by Site (40) · Bone Diseases (38) · Neoplasms (27) · Neoplasms by Histologic Type (16) · Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (13) · Neoplasms, Connective and Soft Tissue (12) · Male Urogenital Diseases (11) · Urogenital Diseases (11) · Urogenital Neoplasms (11) · Neoplasms, Connective Tissue (10) · Neoplastic Processes (10) · Lung Diseases (9) · Neoplasms, Bone Tissue (9)
Irinotecan (4) · Doxorubicin (3) · Cyclophosphamide (2) · Magnetic Resonance Spectroscopy (2) · Temozolomide (2) · Vincristine (2) · 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-f)indol-7-yl)-pyrrole-2,5-dione (1) · Albumin-Bound Paclitaxel (1) · Biological Therapy (1) · Carboplatin (1) · Drug Therapy (1) · Etanercept (1) · Etoposide (1) · Ferrosoferric Oxide (1) · Gemcitabine (1)
Stanford University (4) · Costantino Errani (2) · InSightec (2) · National Cancer Institute (NCI) (2) · Shanghai 6th People's Hospital (2) · The University of Texas Health Science Center at San Antonio (2) · UMC Utrecht (2) · University of Florida (2) · Actuate Therapeutics Inc. (1) · Cedars-Sinai Medical Center (1) · Centre de recherche du Centre hospitalier universitaire de Sherbrooke (1) · China Medical University Hospital (1) · Dana-Farber Cancer Institute (1) · Daniel Bernstein (1) · Emerald Clinical Inc. (1)
United States (24) · France (4) · Netherlands (4) · Italy (3) · Belgium (2) · Canada (2) · China (2) · Taiwan (2) · Finland (1) · Germany (1) · Israel (1) · Portugal (1) · Spain (1) · Switzerland (1) · Turkey (Türkiye) (1)
Mark T. Scarborough, M.D. (2) · Andrew Quon (1) · Arun A Rangaswami (1) · Barry Sugarman (1) · Celina H Shirazipour, Ph.D. (1) · Charles R Thomas, Jr, MD (1) · Christophe Szymanski, MD (1) · Daniel Bernstein (1) · Elizabeth Lowe (1) · Francesco M. Marincola (1) · Gaber Komar, PhD, MD (1) · Heike E Daldrup-Link, MD (1) · Heikki Minn, Professor, MD (1) · Helena M Verkooijen, MD, PhD (1)
PMID 24327518, PMID 27424289, PMID 28053024, PMID 28672195, PMID 29149611, PMID 29383130, PMID 29846250, PMID 30405781, PMID 30519467, PMID 30975030, PMID 31101621, PMID 31401903, PMID 31533931, PMID 31831767, PMID 31882719, PMID 31894292, PMID 35815408, PMID 36582001, PMID 37119875, PMID 41981308
2017 (1), R01CA264248 (1), R01GM114102 (1)