15 completed, 5 unknown, 4 recruiting, 1 not yet recruiting. 5 Not applicable, 4 Phase 1, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Unknown 2, Recruiting 1 |
| Phase 1 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
Follow Blood Coagulation Disorder: new trials by email Literature Review of Blood Coagulation Disorder trials Research Report on Blood Coagulation Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Clinical Ranges of Whole Blood Clotting Times of Patients on Anticoagulants Whole Blood Clotting Time - Blood Coagulation Disorder | Not yet recruiting | Perosphere Technologies Inc. | 120 | 2025-03-01 | 2024-10-08 | |
| Comparative Study of Tranexamic Acid Dosing in Cardiac Surgery Tranexamic acid at a dose of 10 mg/kg followed by 1 mg/kg/h, Tranexamic acid at a dose of 20 mg/kg, Tranexamic acid at a dose of 30 mg/kg - Blood Coagulation Disorder, Postoperative Blood Loss | Not applicable | Recruiting | University of Ioannina | 150 | 2024-05-14 | 2025-09-10 |
| The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) HMPL-523 - Immune Thrombocytopenia, Blood Platelet Disorder | Phase 1 | Withdrawn | Hutchmed | 2024-04-02 | 2025-09-16 | |
| The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin Unfractionated heparin, Double-legged cycle ergometer exercise, Single-legged cycle ergometer exercise, with unfractionated heparin injection in the exercising leg - Blood Coagulation Disorder | Phase 4 | Completed | Kristian Karstoft | 23 | 2023-09-22 | 2024-06-26 |
| Biomarkers and Prediction of Tigecycline Induced Coagulation Dysfunction Blood Coagulation Disorder | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 200 | 2023-05-01 | 2023-04-19 | |
| Transfusion Surveillance in Anaesthesia Transfusion - Transfusion Reaction, Transfusion Related Complication | Recruiting | Erasme University Hospital | 50000 | 2022-09-01 | 2025-09-02 | |
| Hypercoagulability Study Using Haemostatic Techniques in Patients With Inflammatory Bowel Disease rotational thromboelastometry - Inflammatory Bowel Diseases, Thrombosis | Unknown | Hospital Universitario La Paz | 50 | 2020-11-18 | 2021-07-23 | |
| Ondansetron and Blood Coagulation 0 ul of ondansetron, 0.2 ul of ondansetron, 2 ul of ondansetron - Blood Coagulation Disorder | Not applicable | Unknown | Seoul National University Bundang Hospital | 12 | 2020-09-16 | 2023-03-15 |
| Palonosetron and Blood Coagulation 0 ul of palonosetron, 1 ul of palonosetron, 10 ul of palonosetron - Blood Coagulation Disorder | Not applicable | Unknown | Seoul National University Bundang Hospital | 12 | 2020-09-16 | 2023-03-15 |
| AAV Gene Therapy Screening/Observational Protocol (ECLIPSE) Hemophilia B, Blood Coagulation Disorders, Inherited | Completed | Spur Therapeutics | 37 | 2020-02-14 | 2022-11-04 | |
| Dexmedetomidine and Blood Coagulation 0 ul of dexmedetomidine, 0.25 ul of dexmedetomidine, 0.5 ul of dexmedetomidine - Blood Coagulation Disorder | Completed | Seoul National University Bundang Hospital | 11 | 2020-02-12 | 2021-07-02 | |
| Comparison of Two D-Dimers Dosing Techniques Blood Coagulation Disorder | Completed | University Hospital, Brest | 3027 | 2019-07-01 | 2021-06-07 | |
| Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors SPK-8016 - Adeno-Associated Virus (AAV), Blood Coagulation Disorder | Phase 1 / Phase 2 | Completed | Spark Therapeutics, Inc. | 4 | 2019-01-30 | 2024-02-23 |
| Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants Standard of Care FVIII Replacement therapy - Blood Coagulation Disorder, Blood Coagulation Disorders, Inherited | Completed | Spark Therapeutics, Inc. | 25 | 2019-01-21 | 2023-07-10 | |
| NOAC Plasma Concentration and Blood Coagulation in Healthy Volunteers Edoxaban 60 MG - Blood Coagulation Disorder | Phase 4 | Completed | Turku University Hospital | 15 | 2018-11-26 | 2019-09-17 |
| Sequential Compression Devices Effect on Fibrinolysis in Plastic Surgery Outpatients Sequential compression devices (SCDs), No sequential compression. - Blood Coagulation Disorder | Not applicable | Completed | Swanson Center | 50 | 2018-11-01 | 2019-01-31 |
| Noninvasive Measurement of Blood Coagulation Measurement of coagulability of blood - Anticoagulants; Increased, Anticoagulant Overdosage | Unknown | Meir Medical Center | 140 | 2017-08-01 | 2017-07-19 | |
| Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD) PAS assay, TGT - Thrombosis, Blood Coagulation Disorder | Recruiting | Scientific Institute San Raffaele | 60 | 2017-06-29 | 2025-05-15 | |
| Plasmalyte-148 Solution and Blood Coagulation Plasmalyte-148 - Blood Coagulation Disorder | Completed | Seoul National University Hospital | 12 | 2017-05-15 | 2020-02-13 | |
| Irrigating Fluid and Blood Coagulation A mixture of 2.7% sorbitol-0.54% mannitol solution - Blood Coagulation Disorder | Completed | Seoul National University Bundang Hospital | 12 | 2017-03-10 | 2017-04-07 |
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Blood Coagulation Disorders (27) · Thrombosis (6) · Hemorrhage (5) · Hematologic Diseases (4) · Hemorrhagic Disorders (4) · Blood Coagulation Disorders, Inherited (3) · Coagulation Protein Disorders (2) · Drug-Related Side Effects and Adverse Reactions (2) · Genetic Diseases, Inborn (2) · Genetic Diseases, X-Linked (2) · Hemophilia A (2) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Atrial Fibrillation (1) · Autoimmune Diseases (1)
Hemic and Lymphatic Diseases (27) · Hematologic Diseases (23) · Cardiovascular Diseases (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Embolism and Thrombosis (6) · Pathological Conditions, Signs and Symptoms (6) · Vascular Diseases (6) · Pathologic Processes (5) · Chemically-Induced Disorders (2) · Congenital Abnormalities (2) · Digestive System Diseases (2) · Gastrointestinal Diseases (2) · Genetic Diseases, Inborn (2) · Genetic Diseases, X-Linked (2) · Heart Diseases (2)
Blood Transfusion (1) · Bulk Drugs (1) · Dexmedetomidine (1) · Fibrinogen (1) · Heart Rate (1) · Heparin (1) · Motion Pictures (1) · Ondansetron (1) · Palonosetron (1) · Surveys and Questionnaires (1) · Whole Blood Coagulation Time (1) · edoxaban (1)
Seoul National University Bundang Hospital (4) · Spark Therapeutics, Inc. (2) · Centre Hospitalier Universitaire Vaudois (1) · Christian Fenger-Eriksen (1) · Erasme University Hospital (1) · Hospital Universitario La Paz (1) · Hospitalsenheden Vest (1) · Hutchmed (1) · Kristian Karstoft (1) · Leiden University Medical Center (1) · Meir Medical Center (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Perosphere Technologies Inc. (1) · Scientific Institute San Raffaele (1) · Seoul National University Hospital (1)
United States (8) · South Korea (5) · Australia (3) · Denmark (3) · Belgium (2) · Canada (2) · France (2) · Germany (2) · Italy (2) · Spain (2) · Austria (1) · Finland (1) · Greece (1) · Ireland (1) · Netherlands (1)
Hyo-Seok Na, MD., PhD. (3) · Banne Nemeth, MD (1) · Eric Swanson, M.D. (1) · Evangelia Samara (1) · Filippo Consolo, PhD (1) · Hyo-Seok Na, PhD (1) · Hyun-Jung Shin, PhD (1) · Kristian Karstoft, MD, DMSc (1) · Marcin Wlodarski, MD, PhD (1) · Peter H Chang, D.O. (1) · Pratima Chowdary, Dr (1) · Steen Husted, MD, PhD (1) · Stefano Di Bernardo, MD (1)
PMID 26673787, PMID 29475179, PMID 30608563, PMID 31157681, PMID 31249952, PMID 34268623, PMID 34282539, PMID 34718493, PMID 37409664, PMID 40643853
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