Ards: Clinical Trials

129 completed, 81 unknown, 28 recruiting, 16 terminated. 97 Not applicable, 42 Phase 2, 17 Phase 1, 12 Phase 3, 5 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	97	Completed 46, Unknown 29, Recruiting 12, Not yet recruiting 5, Active not recruiting 2, Terminated 2, Withdrawn 1
Phase 2	42	Completed 15, Terminated 10, Recruiting 7, Withdrawn 6, Unknown 3, Not yet recruiting 1
Phase 1	17	Completed 10, Terminated 2, Unknown 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1
Phase 3	12	Completed 3, Terminated 3, Unknown 3, Not yet recruiting 1, Recruiting 1, Withdrawn 1
Phase 4	5	Completed 2, Unknown 2, Terminated 1
Early Phase 1	2	Terminated 1, Unknown 1

Follow this condition Literature Review of Ards trials Research Report on Ards

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress Lift mobile mindfulness, Enlighten Recovery education program - Critical Illness, Heart Failure	Not applicable	Not yet recruiting	Duke University	450	2027-01-01	2026-07-08
Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS AVM0703, Placebo - ARDS, Covid19	Phase 1	Not yet recruiting	AVM Biotechnology Inc	16	2026-12-01	2025-10-02
Assessment of Blood Viscosity in ARDS (Acute Respiratory Distress Syndrome) Blood draws (peripheral venous puncture), Blood draws (arterial catheter, central venous line, or Swan-Ganz catheter) - ARDS		Not yet recruiting	Hospices Civils de Lyon	46	2026-10-01	2026-09-16
Mechanical Power and Mortality in Mechanically Ventilated Adults Mechanical Ventilation Complication, Ventilator Induced Lung Injury		Not yet recruiting	Zagazig University	116	2026-09-10	2026-09-23
Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults Placebo, Fostamatinib - Acute Respiratory Distress Syndrome, ARDS	Phase 2	Not yet recruiting	Inova Health Care Services	40	2026-08-30	2026-02-02
TwichView-guided Atricurium Dose Adjustment Trial EMG-based quantitative TOF-guided atracurium titration - ARDS, TTM	Not applicable	Recruiting	Fu Jen Catholic University Hospital	120	2026-08-19	2026-09-08
Fibrinogen-to-Albumin Ratio as a Predictor of Acute Respiratory Distress Syndrome in Traumatic Brain Injury Fibrinogen-to-albumin ratio - Fibrinogen, Albumin		Recruiting	Tanta University	350	2026-07-01	2026-10-09
Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS Human umbilical cord mesenchymal stem cells + best supportive care, Placebo control + best supportive care - COVID-19, ARDS	Phase 1 / Phase 2	Withdrawn	Baylx Inc.		2026-06-01	2025-12-29
A Controlled Study to Evaluate the Efficacy of Allogeneic MesenCure for the Treatment of Patients With ARDS MesenCure, Placebo - ARDS	Phase 3	Not yet recruiting	BonusBio Group Ltd	300	2026-04-01	2025-08-11
Machine Learning Prediction of Mortality After Prone Positioning in ARDS Prone Position Ventilation - Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation		Completed	Shanghai Zhongshan Hospital	358	2026-03-01	2026-08-14
HemodynamIc eFfects of Lung Collapse and overdIstension During ARDS Change in PEEP - ARDS, AHRF	Not applicable	Not yet recruiting	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	20	2026-02-28	2026-02-20
Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe ARDS enteral nutrition through nasojejunal tube, enteral nutrition through nasogastric tube - ARDS	Not applicable	Recruiting	Southeast University, China	40	2026-01-20	2026-01-23
Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome Instilled T3, Placebo Therapy - Covid19, SARS-CoV Infection	Phase 2	Withdrawn	University of Minnesota		2026-01-15	2026-02-10
High PEEP in Noninvasive Ventilation Patients With Pneumonia or ARDS The level of PEEP during noninvasive ventilation - Noninvasive Ventilation, Pneumonia	Not applicable	Recruiting	Chongqing Medical University	706	2026-01-04	2026-01-07
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm) - Congenital Heart Disease, Cardiopulmonary Bypass	Phase 1 / Phase 2	Recruiting	Charite University, Berlin, Germany	80	2025-12-05	2026-10-15
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab Cohort C: bevacizumab, Cohort C: placebo - Acute Respiratory Distress Syndrome (ARDS), ARDS	Phase 2	Recruiting	PPD Development, LP	200	2025-10-28	2026-07-31
Electrical Impendance Tomography Usage in ICU ARDS, Alveolar Recruitment Manoeuvres		Not yet recruiting	Erasme University Hospital	1000	2025-10-15	2025-09-22
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab Cohort A: vilobelimab, Cohort A: placebo - Acute Respiratory Distress Syndrome (ARDS), ARDS	Phase 2	Recruiting	PPD Development, LP	200	2025-06-21	2026-07-31
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record) Cohort A: vilobelimab, Cohort A: placebo, Cohort B: paridiprubart - Acute Respiratory Distress Syndrome (ARDS), ARDS	Phase 2	Recruiting	PPD Development, LP	600	2025-06-10	2026-07-31
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart Cohort B: paridiprubart, Cohort B: placebo - Acute Respiratory Distress Syndrome (ARDS), ARDS	Phase 2	Recruiting	PPD Development, LP	200	2025-06-10	2026-07-31

Showing 20 of 283. Sign in to see all of them.

Narrower conditions

COVID-19 (77)  ·  Respiratory Distress Syndrome (46)  ·  Acute Lung Injury (37)  ·  Respiratory Insufficiency (28)  ·  Critical Illness (19)  ·  Pneumonia (17)  ·  Coronavirus Infections (16)  ·  Sepsis (12)  ·  Ventilator-Induced Lung Injury (10)  ·  Respiratory Aspiration (7)  ·  Severe Acute Respiratory Syndrome (7)  ·  Shock, Septic (7)  ·  Hypoxia (6)  ·  Dyspnea (5)  ·  Acute Kidney Injury (4)

Broader conditions

Respiratory Tract Diseases (165)  ·  Lung Diseases (145)  ·  Infections (109)  ·  Respiratory Tract Infections (91)  ·  RNA Virus Infections (82)  ·  Coronaviridae Infections (81)  ·  Nidovirales Infections (81)  ·  Virus Diseases (81)  ·  Respiration Disorders (76)  ·  Pneumonia, Viral (74)  ·  Pneumonia (73)  ·  Coronavirus Infections (66)  ·  Pathological Conditions, Signs and Symptoms (64)  ·  Pathologic Processes (50)  ·  Lung Injury (46)

Interventions

Prone Position (9)  ·  Blood Specimen Collection (8)  ·  Respiration, Artificial (6)  ·  Bronchoscopy (4)  ·  Echocardiography (4)  ·  Supine Position (4)  ·  Ventilators, Mechanical (4)  ·  Meropenem (3)  ·  Standard of Care (3)  ·  Surveys and Questionnaires (3)  ·  aviptadil (3)  ·  Ascorbic Acid (2)  ·  Calcium Dobesilate (2)  ·  Control Groups (2)  ·  Dexamethasone (2)

Sponsors

Southeast University, China (14)  ·  Central Hospital, Nancy, France (6)  ·  Assistance Publique - Hôpitaux de Paris (4)  ·  Assistance Publique Hopitaux De Marseille (4)  ·  Centre Hospitalier Universitaire, Amiens (4)  ·  King Abdul Aziz Specialist Hospital (4)  ·  Medical University of Vienna (4)  ·  PPD Development, LP (4)  ·  Policlinico Hospital (4)  ·  Unity Health Toronto (4)  ·  University of Sao Paulo General Hospital (4)  ·  University of Zurich (4)  ·  Charite University, Berlin, Germany (3)  ·  Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (3)  ·  Direct Biologics, LLC (3)

Countries

United States (53)  ·  France (41)  ·  China (38)  ·  Italy (20)  ·  Germany (19)  ·  Canada (12)  ·  Spain (8)  ·  Switzerland (8)  ·  Netherlands (7)  ·  Taiwan (7)  ·  Austria (6)  ·  Brazil (6)  ·  Chile (6)  ·  Egypt (6)  ·  Israel (6)

Top investigators

Bill Arana (3)  ·  Shi Yuan, PhD,MD (3)  ·  Arie Soroksky, M.D. (2)  ·  Eddy Fan, MD, PhD (2)  ·  Hongping Qu (2)  ·  Jonathan C Javitt, MD, MPH (2)  ·  Marcelo BP Amato (2)  ·  Mike Royal, MD (2)  ·  Adam Schrum, PhD (1)  ·  Adrian Covic, Professor (1)

Results publications

PMID 23688302, PMID 10793162, PMID 18451319, PMID 20843245, PMID 26903337, PMID 33177145, PMID 34425070, PMID 8844239, PMID 10488881, PMID 10924859, PMID 11529210, PMID 11594172, PMID 11719318, PMID 11723675, PMID 12421743, PMID 12694139, PMID 12910335, PMID 14605526, PMID 14693669, PMID 15231405, PMID 15269312, PMID 15818103, PMID 16134000, PMID 16249926, PMID 16387935, PMID 16556697, PMID 16641394, PMID 16694380, PMID 16714767, PMID 16953900, PMID 17316468, PMID 18195629, PMID 18270352, PMID 1830582, PMID 18312626, PMID 18431279, PMID 18993042, PMID 19001507, PMID 19272543, PMID 19325511, PMID 19652949, PMID 19869306, PMID 20197533, PMID 20225074, PMID 20851923, PMID 21093515, PMID 21118369, PMID 21297069, PMID 21659748, PMID 21752095

NIH funding

1UG3AT013109-01 (1), R01HL141608 (1)