9 completed, 5 recruiting, 4 unknown, 2 enrolling by invitation. 14 Not applicable, 1 Early Phase 1, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 7, Recruiting 3, Unknown 2, Active not recruiting 1, Enrolling by invitation 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Apraxia of Speech: new trials by email Literature Review of Apraxia of Speech trials Research Report on Apraxia of Speech
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| taVNS for Speech and Language Recovery in Aphasia taVNS, sham taVNS - Aphasia, Apraxia of Speech | Not applicable | Enrolling by invitation | University of Florida | 12 | 2026-01-01 | 2026-05-04 |
| Measuring Aided Language Development AAC Generative Language Intervention - Down Syndrome, Cerebral Palsy | Not applicable | Recruiting | University of Central Florida | 60 | 2025-04-01 | 2025-05-16 |
| Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech Sound production treatment, Motor Imagery Practice - Apraxia, Oral, Apraxia of Speech | Not applicable | Unknown | University of Central Florida | 18 | 2023-12-11 | 2025-06-26 |
| Searching of Apraxia of Speech in Children With Specific Language Impairment Mansora Arabic test battery for childhood apraxia of speech - Apraxia of Speech | Unknown | Sohag University | 100 | 2022-10-01 | 2022-10-18 | |
| Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation high-definition transcranial direct current stimulation (HD-tDCS) - Primary Progressive Aphasia, Apraxia of Speech | Not applicable | Active not recruiting | The University of Texas at Dallas | 12 | 2022-06-01 | 2026-05-08 |
| MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish Healthcare MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of speech) - Aphasia, Apraxia of Speech | Not applicable | Completed | Karolinska Institutet | 25 | 2021-03-10 | 2023-03-09 |
| Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders C-11 PiB, AV1451 Tau, C-11 ER176 - PSP, CBD | Enrolling by invitation | Mayo Clinic | 500 | 2020-11-01 | 2025-11-21 | |
| Efficacy of START (Startle Rehabilitation Therapy) in the Treatment Stroke-induced Aphasia/Apraxia Startle Adjuvant Rehabilitation Therapy (START) - Stroke, Aphasia | Early Phase 1 | Unknown | Arizona State University | 54 | 2020-07-22 | 2022-02-22 |
| Video Assisted Speech Technology to Enhance Motor Planning for Speech Video Assisted Speech Therapy (VAST) - Autism Spectrum Disorder, Apraxia of Speech | Not applicable | Completed | iTherapy, LLC | 6 | 2019-12-01 | 2023-05-09 |
| Using tDCS in Speech-based Stroke Rehabilitation Soterix 1x1 line tDCS low-intensity stimulator, Sham - Apraxia of Speech | Not applicable | Recruiting | NYU Langone Health | 24 | 2019-01-11 | 2026-06-03 |
| Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia Unison speech (vs. solo), Metrical timing (vs. conversational) - Aphasia, Apraxia of Speech | Not applicable | Completed | MGH Institute of Health Professions | 75 | 2018-12-04 | 2025-05-18 |
| Efficacy of an Intervention for the Children With Severe Speech Sounds Disorders Treatment for Children with Severe Speech Sound Disorders - Speech Sound Disorder, Apraxia of Speech | Not applicable | Unknown | Chinese University of Hong Kong | 20 | 2018-10-01 | 2019-06-26 |
| Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech AV-1451 - PPA, Non-fluent Aphasia | Phase 4 | Recruiting | Mayo Clinic | 50 | 2018-07-01 | 2025-11-12 |
| The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech Testing protocol for the study - Apraxia of Speech, Non-fluent Aphasia | Recruiting | Mayo Clinic | 47 | 2017-08-01 | 2026-05-01 | |
| Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech - Aphasia, Apraxia of Speech | Not applicable | Recruiting | Karolinska Institutet | 30 | 2017-02-02 | 2024-10-31 |
| Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT) EPG Tx, SPT - Apraxia of Speech, Aphasia, Acquired | Not applicable | Completed | VA Office of Research and Development | 6 | 2015-11-02 | 2021-11-04 |
| Treatment Intensity - Apraxia of Speech Sound Production Treatment (SPT) - Aphasia, CVA | Not applicable | Completed | VA Office of Research and Development | 36 | 2015-05-01 | 2022-07-12 |
| Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback - Apraxia of Speech, Aphasia | Completed | University of North Carolina, Chapel Hill | 46 | 2014-03-01 | 2016-05-12 | |
| A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes Combined Aphasia and Apraxia of Speech Treatment (CAAST) - Apraxia of Speech, Aphasia | Not applicable | Completed | VA Office of Research and Development | 4 | 2013-10-21 | 2019-06-19 |
| Treatments of Acquired Apraxia of Speech Sound Production Treatment - Blocked, Sound Production Treatment - Random - Aphasia, Apraxia of Speech | Not applicable | Completed | VA Office of Research and Development | 20 | 2011-08-01 | 2019-03-22 |
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Apraxias (22) · Aphasia (13) · Stroke (6) · Aphasia, Primary Progressive (4) · Speech (4) · Aphasia, Broca (3) · Language (3) · Primary Progressive Nonfluent Aphasia (3) · Cerebral Palsy (2) · Communication Disorders (2) · Frontotemporal Dementia (2) · Speech Disorders (2) · Speech Sound Disorder (2) · Autism Spectrum Disorder (1) · Autistic Disorder (1)
Nervous System Diseases (22) · Neurobehavioral Manifestations (22) · Neurologic Manifestations (22) · Pathological Conditions, Signs and Symptoms (22) · Psychomotor Disorders (22) · Signs and Symptoms (22) · Communication Disorders (16) · Language Disorders (15) · Brain Diseases (13) · Central Nervous System Diseases (13) · Speech Disorders (13) · Mental Disorders (9) · Cardiovascular Diseases (8) · Vascular Diseases (8) · Cerebrovascular Disorders (7)
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole (2) · 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole (1) · GAT (1) · Therapeutics (1)
Mayo Clinic (4) · VA Office of Research and Development (4) · Karolinska Institutet (2) · University of Central Florida (2) · Arizona State University (1) · Chinese University of Hong Kong (1) · Joanne Kurtzberg, MD (1) · MGH Institute of Health Professions (1) · NYU Langone Health (1) · Sohag University (1) · The University of Texas at Dallas (1) · University of Florida (1) · University of North Carolina, Chapel Hill (1) · iTherapy, LLC (1)
United States (18) · Sweden (2) · Egypt (1) · Hong Kong (1)
Julie L Wambaugh, PhD (3) · Adam Buchwald, MD (1) · Adam Jacks, Ph.D. (1) · Ellika Schalling, Ph.D, SLP (1) · Ellika Schalling, Professor (1) · Jennifer Whitwell, PhD (1) · Jessica Sun (1) · Joanne Kurtzberg (1) · John Hart, MD (1) · Keith A Josephs, M.D. MST, MSc (1) · Keith Josephs, MD (1) · Lauren Bislick Wilson, Ph.D. (1) · Lauryn Zipse, PhD (1) · Shannon C Mauszycki, PhD (1)
PMID 23071199, PMID 24687207, PMID 25075917, PMID 26133692, PMID 26384102, PMID 27063676, PMID 27997948, PMID 28084854, PMID 28654945, PMID 28654947, PMID 28655045, PMID 29497746, PMID 29497747, PMID 30054623, PMID 31072155, PMID 31693389, PMID 32011909, PMID 37699161, PMID 41041680
R01DC012519 (1), R01DC021160 (1), R03DC011881 (1), R15DC019231 (1), R21DC020548 (1), R43DC018447 (1)