3 completed, 2 unknown, 1 not yet recruiting, 1 terminated. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 3, Unknown 2, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Apathy: new trials by email Literature Review of Apathy trials Research Report on Apathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Effects of Atomoxetine on Motivation Atomoxetine, Placebo - Apathy | Phase 4 | Not yet recruiting | University of Oxford | 40 | 2026-08-01 | 2026-08-18 |
| Repetitive Transcranial Magnetic Stimulation for Apathy in Alzheimer's Dementia Neurostar repetitive transcranial magnetic stimulator - Apathy, Alzheimer's Dementia | Phase 4 | Completed | Central Arkansas Veterans Healthcare System | 20 | 2014-05-01 | 2019-08-21 |
| Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment:Pilot Study Neurostar repetitive transcranial magnetic stimulator - Apathy, Mild Cognitive Impairment | Phase 4 | Unknown | Central Arkansas Veterans Healthcare System | 14 | 2014-04-01 | 2016-02-10 |
| Evaluation of the Efficacy of Rasagiline in Apathy in Drug-naïve Patients With Parkinson's Disease by a Multi-center Study AZILECT®, Placebo - Drug-naïve Patients With Parkinson's Disease, Apathy | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 50 | 2013-06-01 | 2013-01-10 |
| Exploring the Use of Transdermal Methylphenidate to Reduce Fall Risk in Patients With Dementia. Transdermal Methylphenidate - Dementia, Accidental Falls | Phase 4 | Terminated | St. Louis University | 14 | 2012-11-01 | 2018-07-24 |
| Improving Function, Quality of Life, Glycemia in Diabetics With Dementia Methylphenidate, Placebo - Diabetes Mellitus, Alzheimer's Disease | Phase 4 | Withdrawn | University of Nebraska | 2008-11-18 | 2024-09-23 | |
| Methylphenidate for Apathy in Alzheimer's Dementia: A Controlled Study Methylphenidate, Placebo - Alzheimer's Disease, Apathy | Phase 4 | Completed | VA Office of Research and Development | 60 | 2007-08-01 | 2015-11-20 |
| Wellbutrin XL Effects on SSRIs Induced Changes Wellbutrin XL - Depression, Side Effects | Phase 4 | Completed | Indiana University | 15 | 2004-07-01 | 2007-10-16 |
Lethargy (8) · Alzheimer Disease (4) · Dementia (3) · Cognitive Dysfunction (1) · Depression (1) · Diabetes Mellitus (1) · Sexual Dysfunction, Physiological (1)
Nervous System Diseases (8) · Neurobehavioral Manifestations (8) · Neurologic Manifestations (8) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Mental Disorders (5) · Neurocognitive Disorders (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Neurodegenerative Diseases (4) · Tauopathies (4) · Behavior (1) · Behavioral Symptoms (1) · Cognition Disorders (1) · Dementia (1)
Methylphenidate (3) · Atomoxetine Hydrochloride (1) · Bupropion (1) · Sugars (1) · rasagiline (1)
Central Arkansas Veterans Healthcare System (2) · Indiana University (1) · St. Louis University (1) · University Hospital, Clermont-Ferrand (1) · University of Nebraska (1) · University of Oxford (1) · VA Office of Research and Development (1)
United States (5) · France (1) · United Kingdom (1)
Ahmed A Baig, M.D. (1) · Amit Anand, MD (1) · Catherine J Harmer, DPhil (1) · George T Grossberg, M.D. (1) · Prasad R Padala, M.D. (1) · Prasad R Padala, MD, MS (1) · Prasad R. Padala (1)