36 completed, 19 recruiting, 13 unknown, 8 not yet recruiting. 62 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow Anxiety Depression: new trials by email Literature Review of Anxiety Depression trials Research Report on Anxiety Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-INFORMED PEER-MENTORING BEHAVIORAL INTERVENTION FOR ANXIETY AND DEPRESSION PRIMARY PREVENTION IN YOUTH Peer-mentoring behavioral intervention, Health Education - Anxiety Depression | Not applicable | Not yet recruiting | University of Patras | 1680 | 2027-09-01 | 2026-04-14 |
| Preventive and Personalized Digital Emotion Regulation Skills Intervention to Reduce Depression and Anxiety in Youths With Adverse Childhood Experiences Lifestyle psychoeducation intervention, Personalized digital psychoeducation intervention on emotion regulation - Adverse Childhood Experience, Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | Institute of Mental Health, Singapore | 140 | 2026-12-01 | 2026-11-06 |
| Prevention of Burnout in Spanish Healthcare Professionals Through Attachment-Based Compassion Therapy (ABCT) Attachment-based compassion therapy Compassion, Relaxation program - Burnout Syndrome, Anxiety Depression | Not applicable | Recruiting | Hospital Miguel Servet | 180 | 2026-09-10 | 2026-08-26 |
| Efficacy and Safety of Probiotics for Anxiety Depression Probiotic, Placebo, Escitalopram - Anxiety Depression | Not applicable | Recruiting | Moon (Guangzhou) Biotechnology Co., Ltd. | 60 | 2026-06-15 | 2026-06-29 |
| Calming Minds Study Be Specific, Be Kind, Be Present - Anxiety, Anxiety Depression | Not applicable | Not yet recruiting | University of California, Los Angeles | 500 | 2026-06-08 | 2026-05-11 |
| Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids Education Intervention - Cardiac Arrest, Anxiety Depression | Not applicable | Recruiting | Children's Hospital of Philadelphia | 30 | 2026-06-01 | 2026-07-16 |
| Quality of Life and Functional Outcomes in Laryngeal Cancer Patients Quality of Life Assessment, Patient Satisfaction Assessment, Swallowing Function Assessment - Laryngeal Carcinoma, Quality of Life (QOL) | Not yet recruiting | Saglik Bilimleri Universitesi | 120 | 2026-04-02 | 2026-04-22 | |
| Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep Disorders in China Psychotropic Drugs, Acupuncture - Anxiety Depression, Sleep | Phase 4 | Recruiting | Duke Kunshan University | 180 | 2026-04-01 | 2026-07-29 |
| Group-based ACT for Psychological Distress of Young People Group-based Acceptance and Commitment Therapy, TAU - Depression - Major Depressive Disorder, Depression Anxiety Disorder | Not applicable | Recruiting | Sorlandet Hospital HF | 212 | 2026-03-09 | 2026-06-01 |
| Group Therapy Using the "I-Reconstruction" Psychotherapy Method to Reduce Anxiety Levels Experimental: Active "I-Reconstruction" Therapy, Standard Care (Treatment as Usual) - Anxiety, Anxiety Depression | Not applicable | Recruiting | International Association Psychosomatics And Health Therapy | 36 | 2026-03-02 | 2026-02-09 |
| The REWIRE Behaviour Study Pilot - REWIRE Program, Psychoeducation Control, REWIRE Intervention - Anxiety Depression, Social Media | Not applicable | Not yet recruiting | Gary Goldfield | 220 | 2026-03-01 | 2026-02-24 |
| Prevalence of Psychiatric Problems Among Patients and Healthcare Providers in a Cardiology Department: A Cross-Sectional Study Psychological Assessment using Validated Questionnaires - Anxiety Depression, Burnout | Not yet recruiting | Assiut University | 380 | 2026-01-01 | 2025-12-10 | |
| The Effect of Using Weighted Blanket on Anxiety, Stress, Depression and Comfort Level Among Patients With Cancer Undergoing Intravenous Anticancer Therapy and Its Feasibility of Use by Nurses Compared to Routine Care Weighted Blanket, Regular Hospital Blanket - Solid Cancers, Anxiety Depression | Not applicable | Recruiting | Sultan Qaboos Comprehensive Cancer Center | 152 | 2025-12-25 | 2026-06-17 |
| Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism Exercise-based rehabilitation program - Venous Thromboembolism (VTE), Exercise Therapy | Not applicable | Recruiting | Insel Gruppe AG, University Hospital Bern | 160 | 2025-12-17 | 2026-06-12 |
| Physical Activity Based Treatment for Youth With Depression and Anxiety Confident, Active and Happy youth (CAHY) - Anxiety Depression | Not applicable | Enrolling by invitation | Haukeland University Hospital | 100 | 2025-12-15 | 2026-01-06 |
| SOS for Caregiver Wellbeing Screening, Outcomes and Referral Pathways - Mental Health, Depression and Burden in Caregivers | Not applicable | Active not recruiting | Murdoch Childrens Research Institute | 123 | 2025-10-22 | 2026-10-09 |
| Latinas Integrating Fitness and Therapy Stepped Care Mental Health Counseling, Exercise Program - Stepped Care Cognitive Behavioral Therapy, Exercise | Not applicable | Recruiting | Colorado State University | 20 | 2025-10-01 | 2025-10-31 |
| Acupuncture for Anxiety/Depression in Patients With Breast Cancer Electroacupuncture group, Sham electroacupuncture - Anxiety Depression, Breast Cancer | Not applicable | Not yet recruiting | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 360 | 2025-09-15 | 2025-09-24 |
| Evaluating the Big Five Intervention in Norway Big Five, Gratitude - Anxiety Depression | Not applicable | Recruiting | Haukeland University Hospital | 410 | 2025-09-10 | 2025-10-01 |
| Enhancing Wellbeing in Community Dwelling Seniors Through Structured Arts-Based Programmes in the Active Ageing Centres: A Mixed Method Study. Music / Visual Arts - Wellbeing, Social Isolation in Older Adults | Not applicable | Active not recruiting | SingHealth Community Hospitals | 239 | 2025-08-20 | 2026-10-05 |
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Anxiety Disorders (33) · Depression (31) · COVID-19 (6) · Psychological Well-Being (5) · Breast Neoplasms (4) · Emotional Regulation (4) · Burnout, Psychological (3) · Caregiver Burden (3) · Chronic Disease (2) · Chronic Pain (2) · Depressive Disorder, Major (2) · Fatigue (2) · Health Behavior (2) · Lymphoma, Follicular (2) · Mental Disorders (2)
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