18 completed, 3 terminated, 3 withdrawn, 2 active not recruiting. 19 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Completed 13, Terminated 3, Active not recruiting 2, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Accelerated TMS for MDD TMS - Major Depressive Disorder | Not applicable | Active not recruiting | Neuronetics | 50 | 2025-08-21 | 2026-06-29 |
| Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments Patients treated with NeuroStar TMS, Patients treated with Esketamine - Depression, OCD | Recruiting | Neuronetics | 12000 | 2025-05-15 | 2026-04-09 | |
| Retrospective Analyses of TrakStar Database NeuroStar Advanced TMS Therapy System - Depression, Obsessive-Compulsive Disorder | Recruiting | Neuronetics | 156000 | 2025-02-25 | 2026-04-09 | |
| Symptom Evaluation Following Repetitive Transcranial Magnetic Stimulation rTMS - Neurologic Symptoms | Not applicable | Active not recruiting | Neuronetics | 20 | 2024-05-15 | 2026-06-29 |
| A Retrospective Study to Evaluate NeuroStar® Advanced Therapy in Adolescents Transcranial Magnetic Stimulation - MDD | Completed | Neuronetics | 7690 | 2023-05-01 | 2025-01-06 | |
| Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature repetitive Transcranial Magnetic Stimulation - Major Depressive Disorder | Not applicable | Completed | Neuronetics | 40 | 2022-11-07 | 2025-02-17 |
| Treatment of Major Depressive Disorder in the UK Using TMS Therapy Transcranial Magnetic Stimulator - Major Depressive Disorder | Withdrawn | Neuronetics | 2020-03-01 | 2021-10-08 | ||
| Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression NeuroStar TMS Therapy® System, NeuroStar XPLOR® - Major Depressive Disorder | Not applicable | Completed | Mayo Clinic | 47 | 2018-09-24 | 2024-02-01 |
| rTMS and Botulinum Toxin in Primary Cervical Dystonia NeuroStar TMS therapy, Sham NeuroStar TMS therapy, Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) - Primary Cervical Dystonia, Dystonia | Not applicable | Completed | University of Florida | 9 | 2015-11-01 | 2023-12-22 |
| Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents Active NeuroStar® Transcranial Magnetic Stimulation (TMS), Sham NeuroStar® Transcranial Magnetic Stimulation (TMS) - Major Depressive Disorder | Not applicable | Completed | Neuronetics | 112 | 2015-10-01 | 2025-06-12 |
| rTMS Therapy for Primary Orthostatic Tremor Magstim RapidStim2, Sham Magstim RapidStim2, Fullerton Advanced Balance (FAB) Scale - Primary Orthostatic Tremor | Not applicable | Completed | University of Florida | 10 | 2015-08-01 | 2025-04-02 |
| Determination of Analgesic Effect From One Transcranial Magnetic Stimulation(TMS)Treatment Following Vaginal Reconstructive Surgery. Active Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation - Pain | Not applicable | Withdrawn | East Tennessee State University | 2015-07-01 | 2016-03-08 | |
| rTMS for PTSD Comorbid With Major Depressive Disorder Transcranial Magnetic Stimulation (TMS) - Posttraumatic Stress Disorder, Major Depressive Disorder | Not applicable | Completed | Butler Hospital | 40 | 2014-10-01 | 2018-10-04 |
| Transcranial Magnetic Stimulation Treatment of Hoarding Disorder Neurostar Transcranial Magnetic Stimulation Therapy System - Hoarding | Not applicable | Completed | Hartford Hospital | 1 | 2014-07-01 | 2016-10-06 |
| Transcranial Magnetic Stimulation Treatment for Generalized Anxiety Disorder rTMS Treatment - Generalized Anxiety Disorder | Not applicable | Terminated | Hartford Hospital | 4 | 2014-05-01 | 2017-04-10 |
| rTMS in First Episode Psychosis rTMS, Sham Comparator - Schizophrenia, Schizophreniform Disorder | Not applicable | Completed | Indiana University | 20 | 2014-04-30 | 2023-04-19 |
| Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset NeuroStar Transcranial Magnetic Stimulation (TMS) - Depression, Postpartum | Not applicable | Terminated | Neuronetics | 25 | 2013-12-01 | 2025-02-10 |
| Imaging Biomarkers for TMS Treatment of Depression repetitive Transcranial Magnetic Stimulation (rTMS) - Depression | Not applicable | Completed | University of Michigan | 40 | 2013-09-01 | 2017-04-25 |
| Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Depression and Anxiety Repetitive Transcranial Magnetic Stimulation (rTMS) - Cancer in Remission (Any Type or Stage), Depression | Not applicable | Completed | Northwestern University | 24 | 2012-12-01 | 2026-06-24 |
| Cortical Excitability and Inhibition in MDD Transcranial Magnetic Stimulation (TMS), Magnetic Resonance Spectroscopy and Imaging - Major Depressive Disorder, Recurrent, Mild, Depressive Disorder, Major | Completed | Mayo Clinic | 23 | 2012-10-01 | 2019-10-22 |
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Depressive Disorder, Major (12) · Depression (8) · Generalized Anxiety Disorder (2) · Anxiety Disorders (1) · Bipolar Disorder (1) · Cervical Dystonia, Primary (1) · Depression, Postpartum (1) · Dystonia (1) · Hoarding (1) · Lymphoma, Follicular (1) · Neurologic Manifestations (1) · Obsessive-Compulsive Disorder (1) · Pain (1) · Primary orthostatic tremor (1) · Psychotic Disorders (1)
Transcranial Magnetic Stimulation (11) · Diagnostic Imaging (1) · Drug Delivery Systems (1) · Esketamine (1) · Magnetic Resonance Spectroscopy (1) · Weights and Measures (1)
United States (25) · United Kingdom (1)
Eleanor Cole, PhD (4) · Gretchen J Diefenbach, Ph.D. (3) · Aparna Wagle-Shukla, M.D. (2) · David Brock, MD (1) · David G. Brock, MD (1) · David Mrazek, MD (1) · F. Andrew Kozel, MD, MSCR (1) · Karen Heart (1) · Linda L Carpenter, M.D. (1) · Marc J Dubin, MD, PhD (1) · Mark Demitrack, MD (1) · Mehmet Dokucu, MD, PhD (1) · Mohamed Abdelghani, MBBCh, MSc, MRCPsych (1) · Paul Croarkin, MD (1) · Paul E Croarkin, D.O. (1)
PMID 17573044, PMID 18232722, PMID 18294022, PMID 19330495, PMID 19629020, PMID 20965447, PMID 21951987, PMID 22689344, PMID 23895940, PMID 24360599, PMID 25271871, PMID 26575452, PMID 27198484, PMID 28886760, PMID 29494898, PMID 29677606, PMID 39245178, PMID 40215375, PMID 41367968, PMID 42001086
R01MH113700 (1), R21MH098174 (1)