9 completed, 8 unknown, 7 recruiting, 3 not yet recruiting. 15 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Recruiting 6, Completed 5, Not yet recruiting 2, Unknown 2 |
| Phase 2 | 2 | Unknown 2 |
Follow Anastomotic Leakage: new trials by email Literature Review of Anastomotic Leakage trials Research Report on Anastomotic Leakage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VACStent Use for the Treatment of Anastomotic Leakage Following coloREctal Surgery VacStent GI Colon device - Colorectal Surgery, Anastomotic Leak Rectum | Not applicable | Not yet recruiting | Amsterdam UMC, location VUmc | 40 | 2026-07-01 | 2026-06-08 |
| The Value of Early Postoperative Colonoscopy in The Early Diagnosis of Anastomotic Leakage After Surgery for Low Colorectal Cancer electronic colonoscopy - Anastomotic Leakage | Not applicable | Recruiting | Nanchong Central Hospital | 140 | 2026-06-21 | 2026-06-25 |
| Single-Stapled Technique for Colorectal Anastomosis Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis - Colorectal Cancer, Colorectal Anastomosis | Recruiting | Umeå University | 500 | 2026-01-07 | 2026-02-18 | |
| Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection Somatostatin, Clear Liquid Diet, Prophylactic Diverting Stoma - Rectal Cancer, Anastomotic Leakage | Not applicable | Recruiting | Tongji Hospital | 72 | 2025-11-17 | 2026-05-26 |
| Study on the Correlation Between Serum and Fecal Sialic Acid Levels and Tumor Characteristics as Well as Postoperative Anastomotic Leakage in Patients With Colorectal Tumors Colorectal Neoplasia, Anastomotic Leakage | Not yet recruiting | Xiaolong Li | 1468 | 2025-09-25 | 2025-09-24 | |
| Pre-emptive Endoscopic Vacuum Therapy Reduces the Incidence of Anastomotic Leakage After Colorectal Cancer Surgery PEVT - Colorectal Cancer, Colorectal Surgery | Not applicable | Recruiting | Nanchong Central Hospital | 110 | 2025-09-22 | 2026-04-02 |
| Efficacy and Safety of Colorectal Anastomotic Leak Testing Intraoperative leak testing - Colorectal Cancer, Leakage Testing | Not applicable | Recruiting | Nanchong Central Hospital | 264 | 2024-12-22 | 2026-03-31 |
| TreatmENT of AnastomotiC LeakagE After COLON Cancer Resection Development of a model for predicting 90-day mortality and to compare various treatment strategies for anastomotic leakage - Treatment, Anastomotic Leakage | Unknown | Radboud University Medical Center | 2000 | 2024-10-01 | 2024-07-30 | |
| Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications Continuous Circumferential Reinforcement of the Anastomotic - Colorectal Cancer, Anastomotic Leakage | Phase 2 | Unknown | ZHI-ZHONG PAN | 208 | 2024-07-20 | 2024-07-11 |
| Stapler Reinforcement Patches Compared to Standard Staplers in Gastrojejunostomy Stapler Reinforcement Patch, Standard Stapler - Gastric Cancer, Gastrostomy | Not applicable | Recruiting | Nanchong Central Hospital | 382 | 2024-05-30 | 2026-03-31 |
| D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (intervention), Enoxaparin 40 Mg/0.4 mL Injectable Solution, Levofloxacin 500mg - Blood Loss, Intensive Care | Not applicable | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 80 | 2024-01-02 | 2023-09-22 |
| Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy COLO BT™, Stoma Creation - Colorectal Surgery, Colorectal Cancer | Not applicable | Recruiting | JSR Medical Co., Ltd. | 256 | 2023-12-04 | 2026-08-05 |
| CRP/CT-Guided Selective Ileostomy After LAR Serial C-reactive protein-guided computed tomography surveillance and selective omission of defunctioning ileostomy, routine follow up - Rectal Cancer Patients, Anastomotic Leakage | Not applicable | Completed | Alexandria University | 200 | 2023-01-15 | 2026-09-02 |
| Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery Application of autologous fibrin matrix (Obsidian) - Anastomotic Leak Rectum, Rectal Cancer | Completed | University of Aarhus | 50 | 2021-12-15 | 2024-03-27 | |
| The Relationship Between Drainage Fluid and Anastomotic Leakage After Colorectal Cancer Surgery drainge fluid - Anastomotic Leakage | Unknown | Southwest Hospital, China | 300 | 2021-07-01 | 2022-01-13 | |
| Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective Observational Study Elective or emergency colorectal surgery for cancer, diverticular disease, inflammatory bowel-disease or reversal of Hartmann's procedure - Anastomotic Leakage | Completed | University of Palermo | 207 | 2018-06-01 | 2021-04-15 | |
| SEAL Registry - European Registry for the Effectiveness of LifeSeal® Kit LifeSeal® Kit - Anastomotic Leakage | Unknown | LifeBond Ltd. | 200 | 2016-10-01 | 2018-04-02 | |
| Local Metabolism of the Gastric Tube Reconstruction After Esophagectomy OnZurf Probe - Microdialysis, Ischemia | Not applicable | Completed | Region Skane | 60 | 2016-04-25 | 2020-08-19 |
| Use of the TDT for Prevention of Anastomotic Leakage After Laparoscopic Anterior Resection for Rectal Cancer with TDT, without TDT - Anastomotic Leakage, Rectal Neoplasms | Not applicable | Completed | Third Military Medical University | 560 | 2016-02-01 | 2021-05-07 |
| Predictive Factors for Anastomotic Leakage After Colorectal Surgery No interventions, only data collection - Anastomotic Leakage, Colorectal Cancer | Completed | Maastricht University Medical Center | 774 | 2015-08-01 | 2021-09-29 |
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Anastomotic Leak (27) · Colorectal Neoplasms (6) · Esophageal Neoplasms (4) · Rectal Neoplasms (4) · Postoperative Complications (2) · Colonic Neoplasms (1) · Disease (1) · Hemorrhage (1) · Ischemia (1) · Mediastinitis (1) · Peritonitis (1) · Stomach Neoplasms (1)
Pathologic Processes (27) · Pathological Conditions, Signs and Symptoms (27) · Postoperative Complications (25) · Digestive System Diseases (17) · Digestive System Neoplasms (16) · Gastrointestinal Diseases (16) · Gastrointestinal Neoplasms (16) · Neoplasms (16) · Neoplasms by Site (16) · Intestinal Diseases (11) · Intestinal Neoplasms (11) · Rectal Diseases (10) · Colonic Diseases (7) · Colorectal Neoplasms (5) · Esophageal Diseases (4)
Congresses as Topic (1) · Elective Surgical Procedures (1) · Endoscopy (1) · Enoxaparin (1) · Enterostomy (1) · Levofloxacin (1) · Methods (1) · Mortality (1) · Somatostatin (1) · Water (1) · obsidian (1)
Nanchong Central Hospital (4) · Alexandria University (1) · Amsterdam UMC, location VUmc (1) · Andrey Nikolayevich Zharikov (1) · Fudan University (1) · General Committee of Teaching Hospitals and Institutes, Egypt (1) · Hannover Medical School (1) · Heidelberg University (1) · JSR Medical Co., Ltd. (1) · LifeBond Ltd. (1) · Maastricht University Medical Center (1) · Mansoura University (1) · National Taiwan University Hospital (1) · Odense University Hospital (1) · Radboud University Medical Center (1)
China (10) · Egypt (3) · Netherlands (3) · Denmark (2) · Germany (2) · Italy (2) · Sweden (2) · Belgium (1) · Taiwan (1) · United States (1)
Antonino Agrusa, Professor (1) · Hans de Wilt, Professor (1) · Jan Johansson, PhD (1) · Jochen Wedemeyer, MD (1) · Lene H Iversen, DMSc, PhD (1) · Lijie Tan, MD (1) · Mark A Falvo, MD (1) · Medhat Mohamed Anwar Hamed, Prof (1) · Mostafa Shalaby, M,D., MSc. (1) · Nicole Bouvy, MD, PhD (1) · Niels Qvist, Professor (1) · Oskar Grahn, MD, PhD (1) · Pei-Ming Huang, MD (1) · Pieter Tanis, Professor (1)
PMID 19879566, PMID 24656920, PMID 27282451, PMID 30719528, PMID 34613330, PMID 37988156, PMID 40375249, PMID 42875765