41 completed, 14 unknown, 7 recruiting, 3 terminated. 18 Phase 2, 16 Not applicable, 11 Phase 3, 3 Phase 4, 2 Early Phase 1.
Follow Alcoholic Hepatitis: new trials by email Literature Review of Alcoholic Hepatitis trials Research Report on Alcoholic Hepatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A-TANGO Phase 2 Study Placebo, TAK-242, G-CSF (Filgrastim) - Acute-On-Chronic Liver Failure, Alcoholic Hepatitis | Phase 2 | Recruiting | Yaqrit Ltd | 78 | 2026-06-29 | 2026-09-21 |
| PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis N-Acetylcysteine (NAC) Treatment, Prednisolone, Placebo of N-acetylcysteine - Alcoholic Hepatitis | Phase 3 | Recruiting | University Hospital, Lille | 477 | 2026-05-22 | 2026-06-01 |
| Alcohol Consumption and Plasma cfDNA Methylation in Chronic Hepatitis B Alcohol Consumption - Chronic Hepatitis B, Alcoholic Hepatitis | Completed | Beijing Municipal Administration of Hospitals | 85 | 2025-11-21 | 2026-10-08 | |
| Investigating HepQuant DuO Test as a Biomarker in Alcohol-related Liver Disease HepQuant DuO Test - Alcoholic Hepatitis, Alcohol-related Liver Disease | Recruiting | HepQuant, LLC | 40 | 2025-06-10 | 2026-09-16 | |
| Short Course Steroids in Alcohol Associated Hepatitis Prednisolone 40 mg - Alcoholic Hepatitis | Phase 3 | Completed | Asian Institute of Gastroenterology, India | 151 | 2025-04-07 | 2026-09-01 |
| Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis Mycophenolate Mofetil, Prednisone - Alcoholic Hepatitis | Not applicable | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-01-20 | 2025-01-23 |
| Nutritional Interventions in Patients With Alcohol-associated Hepatitis Nutritional supplement - Alcoholic Hepatitis | Not applicable | Unknown | Western University, Canada | 2000 | 2025-01-01 | 2024-05-29 |
| MRG-001 in Patients With Alcoholic Hepatitis MRG-001 - Alcoholic Hepatitis, Acute Alcoholic Hepatitis | Phase 2 | Not yet recruiting | MedRegen LLC | 32 | 2024-09-01 | 2024-03-13 |
| Intra-Hepatic Microbiota in Alcoholic Hepatitis Biological sampling - Cirrhosis, Alcoholic Liver Disease | Recruiting | Hospices Civils de Lyon | 50 | 2024-07-23 | 2026-02-10 | |
| Complex Exploratory Study of Alcohol-Associated Hepatitis Alcoholic Hepatitis | Unknown | Pavol Jozef Safarik University | 100 | 2024-05-01 | 2024-04-10 | |
| Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function Plasma Exchange, Standard Medical Treatment - Alcoholic Hepatitis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 60 | 2024-04-09 | 2024-06-24 |
| Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis Fecal Microbiota Transplantation, Placebo - Alcoholic Hepatitis | Phase 1 / Phase 2 | Unknown | Prasun Kumar Jalal | 50 | 2023-01-21 | 2025-01-23 |
| Utility of the Use of N-acetylcysteine Associated With Conventional Treatment in Patients With Severe Acute Alcoholic Hepatitis (Maddrey> 32) N-acetylcysteine - Alcoholic Hepatitis | Not applicable | Completed | Bioaraba Health Research Institute | 390 | 2022-10-07 | 2026-10-16 |
| HA35 Moderate Alcoholic Hepatitis (AH) Study Sodium Hyaluronate, Placebo - Alcoholic Hepatitis | Early Phase 1 | Recruiting | The Cleveland Clinic | 54 | 2022-09-01 | 2026-09-24 |
| BActeriophages To Treat Liver Disease Eliminating Harmful Bacteria (BATTLE) No intervention - Alcoholic Hepatitis | Unknown | Copenhagen University Hospital, Hvidovre | 30 | 2022-07-01 | 2022-11-16 | |
| Fecal Microbiota Therapy in Steroid Ineligible Alcoholic Hepatitis Fecal Transplantation, Standard Medical Treatment - Alcoholic Hepatitis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 84 | 2022-04-01 | 2022-04-20 |
| CytoSorb® in Patients With Acute on Chronic Liver Failure CytoSorb® treatment - Acute on Chronic Liver Failure, Alcoholic Hepatitis | Withdrawn | CytoSorbents Europe GmbH | 2022-03-15 | 2022-11-29 | ||
| DUR-928 in Patients With Alcoholic Hepatitis DUR-928 (Moderate AH), DUR-928 (Severe AH) - Alcoholic Hepatitis | Phase 2 | Completed | Craig James McClain | 43 | 2021-06-01 | 2023-10-18 |
| Outcomes Using MARS for Patients With ALF Alcoholic Hepatitis, Acute Liver Failure | Completed | Methodist Health System | 27 | 2021-04-23 | 2026-06-11 | |
| A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment DUR-928 30 mg, DUR-928 90 mg, Placebo+ Standard of Care (SOC) - Alcoholic Hepatitis | Phase 2 | Completed | Durect | 307 | 2021-01-22 | 2024-09-05 |
Showing 20 of 72. Sign in to see all of them.
Hepatitis, Alcoholic (72) · Liver Diseases, Alcoholic (9) · Fibrosis (6) · Alcoholism (5) · Liver Cirrhosis, Alcoholic (5) · Infections (4) · Acute-On-Chronic Liver Failure (3) · Hepatitis (3) · Inflammation (3) · Liver Cirrhosis (3) · Liver Diseases (3) · Acquired Immunodeficiency Syndrome (2) · Carcinoma, Hepatocellular (2) · Hepatitis D (2) · Acute Kidney Injury (1)
Alcohol-Induced Disorders (72) · Alcohol-Related Disorders (72) · Chemically-Induced Disorders (72) · Digestive System Diseases (72) · Substance-Related Disorders (72) · Hepatitis (69) · Liver Diseases (69) · Liver Diseases, Alcoholic (63) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Infections (7) · Fibrosis (6) · Liver Cirrhosis (5) · Mental Disorders (5) · Hepatic Insufficiency (4)
Prednisolone (8) · Acetylcysteine (6) · Granulocyte Colony-Stimulating Factor (5) · Pentoxifylline (3) · Prednisone (3) · Adrenal Cortex Hormones (2) · Blood Specimen Collection (2) · Ethanol (2) · Fecal Microbiota Transplantation (2) · Filgrastim (2) · Methylprednisolone (2) · Mycophenolic Acid (2) · Standard of Care (2) · 25-hydroxycholesterol 3-sulfate (1) · 3-(2-(2-tert-butylphenylaminooxalyl)aminopropionylamino)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid (1)
Institute of Liver and Biliary Sciences, India (6) · University Hospital, Lille (5) · Indiana University (4) · University of Aarhus (4) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · University of Alabama at Birmingham (3) · Asian Institute of Gastroenterology, India (2) · Durect (2) · Erasme University Hospital (2) · Imperial College London (2) · The Cleveland Clinic (2) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Municipal Administration of Hospitals (1) · Bioaraba Health Research Institute (1) · Centre Hospitalier Universitaire, Amiens (1)
United States (23) · India (12) · France (8) · Belgium (5) · Denmark (5) · United Kingdom (5) · Spain (3) · Zambia (3) · Slovakia (2) · South Korea (2) · Australia (1) · Austria (1) · China (1) · Finland (1) · Germany (1)
Michael J Vinikoor, MD (3) · Naga Chalasani, MD (2) · Ajay Duseja, DM (1) · Ali R Ahmadi, MD PhD (1) · Arun J Sanyal, MD (1) · Ashwini Kumar Singal, MD (1) · Christophe Moreno, MD, PhD (1) · Clair A Francomano, MD (1) · Craig J McClain, M.D. (1) · David Hagerty, MD (1) · Dharmesh Kapoor (1) · Dong Joon Kim, M.D., Ph.D. (1) · Dr. Jaya Benjamin, PhD (1)
PMID 37011138, PMID 38215876, PMID 11605686, PMID 11943418, PMID 14647046, PMID 15122768, PMID 1531090, PMID 15618643, PMID 15763232, PMID 16026887, PMID 17204261, PMID 17518367, PMID 19445945, PMID 19553649, PMID 20334708, PMID 21085006, PMID 22070475, PMID 22821948, PMID 23737845, PMID 23855300, PMID 23870864, PMID 24026598, PMID 24029409, PMID 24523762, PMID 24704590, PMID 24766056, PMID 25154291, PMID 25501547, PMID 25901427, PMID 26275112, PMID 26288026, PMID 26406978, PMID 26407526, PMID 26707061, PMID 26822470, PMID 26860769, PMID 27453190, PMID 28265546, PMID 28884082, PMID 29391265, PMID 29502183, PMID 29648725, PMID 30244215, PMID 30577864, PMID 31228214, PMID 33074470, PMID 34756674, PMID 34763711, PMID 34862610, PMID 35202597
U01AA021788 (2), U01AA021840 (2), U01AA021886 (2), 2014 (1), 2025 (1), K01TW009998 (1), P50AA027054 (1), R21AA014269 (1), U01AA021883 (1), U01AA021891 (1), U01AA021908 (1), U01AA026934 (1), U01AA026966 (1)