3 completed, 3 recruiting, 2 unknown, 1 not yet recruiting. 9 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 3, Recruiting 3, Unknown 2, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Adjustment Disorders: new trials by email Literature Review of Adjustment Disorders trials Research Report on Adjustment Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders MDMA - Post-Traumatic Stress Disorder, Adjustment Disorders | Phase 2 | Not yet recruiting | Nautilus Sanctuary | 30 | 2026-10-01 | 2026-05-05 |
| Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder Psilocybin therapy - Adjustment Disorder, Adjustment Disorder With Anxious Mood | Phase 2 | Recruiting | Psyence Australia Pty Ltd | 87 | 2025-10-01 | 2026-10-29 |
| RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses RE104 for Injection - Adjustment Disorder | Phase 2 | Recruiting | Reunion Neuroscience Inc | 100 | 2025-07-30 | 2026-11-10 |
| MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other MDMA - Cancer, Adjustment Disorders | Phase 2 | Recruiting | Sunstone Medical | 20 | 2022-10-06 | 2026-05-04 |
| Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma Propranolol, Placebo - Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder | Phase 2 | Unknown | Douglas Mental Health University Institute | 150 | 2021-08-01 | 2021-07-29 |
| Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators Propranolol Hydrochloride, Placebo - Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders | Phase 2 | Unknown | Douglas Mental Health University Institute | 64 | 2017-03-30 | 2021-06-18 |
| The Trauma of Betrayal: Treating Adjustment Disorder With Reconsolidation Blockade Under Propranolol Propranolol Pill - Adjustment Disorders, Posttraumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Douglas Mental Health University Institute | 84 | 2015-11-01 | 2022-12-19 |
| Improve: Integrating Emotion Focused Components Into Psychological Therapy Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT), Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR) - Unipolar Depression, Anxiety Disorder | Phase 2 | Completed | University of Bern | 104 | 2015-04-01 | 2019-09-10 |
| The Efficacy of Parent Involvement in the Treatment of Adolescent Depression Interpersonal Psychotherapy for Depressed Adolescents, Interpersonal Psychotherapy for Depressed Adolescents and Parents - Major Depressive Disorder, Dysthymic Disorder | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 15 | 2009-01-01 | 2012-04-13 |
Stress Disorders, Post-Traumatic (4) · Neoplasms (3) · Trauma and Stressor Related Disorders (3) · Anxiety Disorders (2) · Depression (2) · Stress Disorders, Traumatic, Acute (2) · Amyotrophic Lateral Sclerosis (1) · Breast Neoplasms (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Dysthymic Disorder (1) · Endometrial Neoplasms (1) · Idiopathic Pulmonary Fibrosis (1) · Kidney Neoplasms (1)
Mental Disorders (9) · Trauma and Stressor Related Disorders (6) · Stress Disorders, Traumatic (4) · Behavior (2) · Behavioral Symptoms (2) · Mood Disorders (2) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Breast Diseases (1) · Central Nervous System Diseases (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1) · Depressive Disorder (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1)
Propranolol (3) · N-Methyl-3,4-methylenedioxyamphetamine (2) · Injections (1) · Interpersonal Psychotherapy (1)
Douglas Mental Health University Institute (3) · Nautilus Sanctuary (1) · New York State Psychiatric Institute (1) · Psyence Australia Pty Ltd (1) · Reunion Neuroscience Inc (1) · Sunstone Medical (1) · University of Bern (1)
United States (4) · Canada (3) · Australia (1) · Switzerland (1)
Alain Brunet, Ph.D. (1) · Alain Brunet, PhD. (1) · Casey Paleos, M.D. (1) · Franz Caspar, Prof. PhD (1) · Manish Agrawal, MD (1) · Mark Pollack, Chief Medical Officer (1) · Neil Maresky (1) · Willa Hall, Ph.D. (1)