8 recruiting, 5 completed, 5 unknown, 3 terminated. 8 Phase 1, 7 Phase 2, 2 Early Phase 1, 2 Not applicable, 2 Phase 3.
Follow Adenovirus: new trials by email Literature Review of Adenovirus trials Research Report on Adenovirus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 25BT056: Basket Study of Viral Cytotoxic T Lymphocytes Virus-Specific Cytotoxic T Lymphocytes (vCTLs) - EBV Viremia, CMV Viremia | Early Phase 1 | Not yet recruiting | Children's Hospital of Philadelphia | 35 | 2026-11-01 | 2026-10-22 |
| ELderly REspiratory VIral Cohort Respiratory viral infection - Influenza Viruses, Respiratory Syncytial Virus (RSV) | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1000 | 2026-10-01 | 2026-09-10 | |
| Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone Standard of Care Antiviral medications, Viral CTLs - CMV, AdV Infection | Phase 3 | Recruiting | New York Medical College | 138 | 2026-09-01 | 2026-09-11 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity Adenovirus Specific T- Lymphocytes, Cytomegalovirus Specific T-Lymphocytes, Epstein-Barr Virus Specific T-Lymphocytes - Adenovirus, Cytomegalovirus Infections | Phase 1 / Phase 2 | Recruiting | Jessie L. Alexander | 25 | 2025-04-30 | 2025-08-14 |
| R-MVST Cells for Treatment of Viral Infections in Children and Young Adults Rapidly generated virus specific T (R-MVST) cells - Epstein-Barr Virus, Cytomegalovirus Infections | Phase 1 | Recruiting | Monica Bhatia | 18 | 2025-04-20 | 2026-07-30 |
| LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia LIAISON NES FLU A/B, RSV, & COVID-19, LIAISON PLEX Respiratory Flex Assay - Influenza A, Influenza Type B | Not applicable | Unknown | DiaSorin Molecular LLC | 1000 | 2024-05-06 | 2024-04-30 |
| Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus Infection Bentelan, Placebo - Adenovirus | Phase 3 | Unknown | A.O.U. Città della Salute e della Scienza | 80 | 2024-03-20 | 2024-03-21 |
| Anti-viral T-cell Therapy by Gamma Capture Specific T- Lymphocytes - Adenovirus, Cytomegalovirus Infections | Phase 1 / Phase 2 | Enrolling by invitation | Paul Szabolcs | 25 | 2024-01-08 | 2026-06-29 |
| Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell Transplantation VST infusion, CliniMACS - Cytomegalovirus, Adenovirus | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 42 | 2023-08-01 | 2026-02-23 |
| R-MVST Cells for Treatment of Viral Infections Rapidly generated virus specific T (R-MVST) cells - Epstein-Barr Virus Infections, Cytomegalovirus Infections | Phase 1 | Recruiting | Columbia University | 36 | 2022-05-03 | 2026-06-10 |
| Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes, Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes - Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Cytomegalovirus | Early Phase 1 | Recruiting | Sumithira Vasu | 20 | 2020-11-07 | 2026-09-24 |
| Viral Specific T-Lymphocytes to Treat Adenovirus, CMV and EBV Adenovirus Specific T- Lymphocytes, Cytomegalovirus Specific T-Lymphocytes, EBV Specific T-Lymphocytes - Adenovirus, Cytomegalovirus Infections | Phase 1 / Phase 2 | Terminated | Jessie L. Alexander, MD | 8 | 2020-08-12 | 2026-05-27 |
| Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia Brincidofovir, Standard of Care - Adenovirus | Phase 2 | Withdrawn | Jazz Pharmaceuticals | 2018-12-15 | 2021-07-21 | |
| Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection cytotoxic t-lymphocytes - Adenovirus, Primary Immune Deficiency Disorder | Phase 2 | Recruiting | New York Medical College | 20 | 2018-11-01 | 2026-10-23 |
| The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation Standard of Care, Brincidofovir - Adenovirus | Phase 2 | Terminated | Jazz Pharmaceuticals | 29 | 2017-12-22 | 2021-01-25 |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics Adenovirus | Unknown | Heba Momen kamel | 50 | 2017-11-01 | 2017-10-30 | |
| Specific Respiratory Infections as Triggers of Acute Medical Events Influenza, Human, Respiratory Syncytial Virus Infections | Completed | University College, London | 787000 | 2016-09-01 | 2017-05-04 | |
| A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304 Brincidofovir - Adenovirus | Terminated | Jazz Pharmaceuticals | 100 | 2015-02-01 | 2017-01-09 | |
| Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL) CTL for CMV seropositive donors, CTL for CMV naïve donors - EBV, CMV | Phase 1 | Completed | Catherine Bollard | 27 | 2014-02-01 | 2025-07-03 |
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Adenoviridae Infections (28) · Cytomegalovirus Infections (8) · Epstein-Barr Virus Infections (8) · Enterovirus Infections (2) · Influenza, Human (2) · Meningitis (2) · Paramyxoviridae Infections (2) · Primary Immunodeficiency Diseases (2) · Whooping Cough (2) · Anxiety Disorders (1) · Arenaviridae Infections (1) · Arrhythmias, Cardiac (1) · Autistic Disorder (1) · Bipolar Disorder (1) · Bradycardia (1)
DNA Virus Infections (28) · Infections (27) · Virus Diseases (27) · Herpesviridae Infections (11) · Tumor Virus Infections (8) · RNA Virus Infections (5) · Pathological Conditions, Signs and Symptoms (4) · Respiratory Tract Diseases (4) · Respiratory Tract Infections (4) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Immune System Diseases (3) · Mononegavirales Infections (3)
brincidofovir (4) · Cell Count (2) · Standard of Care (2) · Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Betamethasone (1) · Bosentan (1) · Cefepime (1) · Cidofovir (1) · Ciprofloxacin (1) · Clozapine (1) · Fosfomycin (1) · Haloperidol (1) · Labetalol (1)
Jazz Pharmaceuticals (4) · New York Medical College (2) · A.O.U. Città della Salute e della Scienza (1) · Assistance Publique - Hôpitaux de Paris (1) · Catherine Bollard (1) · Children's Hospital of Philadelphia (1) · Columbia University (1) · Daniel Benjamin (1) · DiaSorin Molecular LLC (1) · Heba Momen kamel (1) · Institut Pasteur du Cambodge (1) · Jessie L. Alexander (1) · Jessie L. Alexander, MD (1) · Medical College of Wisconsin (1) · Monica Bhatia (1)
United States (18) · Italy (3) · United Kingdom (3) · Australia (2) · Spain (2) · Cambodia (1) · Canada (1) · France (1) · Germany (1) · Ireland (1) · Israel (1) · Netherlands (1) · Poland (1) · Singapore (1) · Taiwan (1)
Jessie Alexander, MD (2) · Mitchell Cairo, MD (2) · Caitlin Elgarten, MD, MSCE (1) · Catherine Bollard, MD (1) · Charlotte MJ Warren-Gash, MRCP PhD (1) · Chi Hornik, PharmD (1) · Claude Flamand, Ph.D. (1) · Claudia Bondone, MD (1) · Janet Farhang, PhD (1) · Julie-An Talano, MD (1) · Monica Bhatia, MD (1) · Naik Swati, MD (1) · Paul Szabolcs, MD (1) · Pawel Muranski, MD (1)
PMID 24614374, PMID 24949994, PMID 26039810, PMID 26926644, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29296867, PMID 29324996, PMID 29435949, PMID 29677389, PMID 30790601, PMID 31219185, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33903114, PMID 34302290, PMID 35370711, PMID 35491971, PMID 41247430