7 completed. 7 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 7 |
| Phase 2 | 5 | Completed 5 |
Follow Adenomatous Polyps: new trials by email Literature Review of Adenomatous Polyps trials Research Report on Adenomatous Polyps
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) Eflornithine, Eflornithine Placebo, Sulindac 150 MG - Familial Adenomatous Polyposis | Phase 3 | Completed | Cancer Prevention Pharmaceuticals, Inc. | 171 | 2013-10-01 | 2021-06-08 |
| Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis Celecoxib, Ursodeoxycholic acid, Placebo - Familial Adenomatous Polyposis, Duodenal Neoplasms | Phase 2 / Phase 3 | Completed | Radboud University Medical Center | 37 | 2009-05-01 | 2013-05-16 |
| S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000 Vitamin E, Selenium, Vitamin E placebo - Colorectal Cancer, Precancerous Condition | Phase 3 | Completed | SWOG Cancer Research Network | 8094 | 2008-06-01 | 2019-12-16 |
| Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA Eicosapentanoic Acid (EPA), Endoscopy, Biopsies taken - Familial Adenomatous Polyposis Coli, FAP | Phase 2 / Phase 3 | Completed | S.L.A. Pharma AG | 58 | 2006-11-01 | 2014-08-22 |
| Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa Eicosapentaenoic Acid (EPA), Endoscopy, Biopsies taken - Adenomatous Polyps | Phase 2 / Phase 3 | Completed | S.L.A. Pharma AG | 120 | 2006-10-01 | 2008-10-17 |
| Vitamin D/Calcium Polyp Prevention Study Calcium Carbonate, Vitamin D3, placebo - Colorectal Cancer, Polyps | Phase 2 / Phase 3 | Completed | Dartmouth-Hitchcock Medical Center | 2813 | 2004-07-01 | 2017-03-15 |
| Aspirin/Folate Prevention of Large Bowel Polyps Aspirin, Folate - Colorectal Cancer, Polyps | Phase 2 / Phase 3 | Completed | Dartmouth-Hitchcock Medical Center | 1121 | 1992-02-01 | 2020-03-13 |
Polyps (5) · Adenoma (3) · Adenomatous Polyposis Coli (3) · Colorectal Neoplasms (3) · Hyperplasia (2) · Colonic Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Duodenal Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Genetic Diseases, Inborn (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1)
Neoplasms (7) · Neoplasms by Histologic Type (7) · Neoplasms, Glandular and Epithelial (7) · Colonic Diseases (6) · Neoplasms by Site (6) · Digestive System Diseases (5) · Digestive System Neoplasms (5) · Gastrointestinal Diseases (5) · Gastrointestinal Neoplasms (5) · Intestinal Diseases (5) · Intestinal Neoplasms (5) · Pathological Conditions, Anatomical (5) · Pathological Conditions, Signs and Symptoms (5) · Adenoma (4) · Colorectal Neoplasms (3)
Eicosapentaenoic Acid (2) · Endoscopy (2) · Aspirin (1) · Calcium Carbonate (1) · Celecoxib (1) · Cholecalciferol (1) · Clinical Chemistry Tests (1) · Colonoscopy (1) · Eflornithine (1) · Folic Acid (1) · Restraint, Physical (1) · Selenium (1) · Sulindac (1) · Ursodeoxycholic Acid (1) · Vitamin E (1)
Dartmouth-Hitchcock Medical Center (2) · S.L.A. Pharma AG (2) · Cancer Prevention Pharmaceuticals, Inc. (1) · Radboud University Medical Center (1) · SWOG Cancer Research Network (1)
United States (4) · United Kingdom (3) · Canada (2) · Netherlands (2) · Belgium (1) · Germany (1) · Italy (1) · Puerto Rico (1) · Spain (1)
Nicholas J West, MB BS FRCS (2) · Bjorn WH van Heumen, MD (1) · Carol Burke, M.D. (1) · Ellen Kampman, Ph D (1) · Fokko M Nagengast, MD, Ph D (1) · James Church, M.D. (1) · John A Baron, MD, MSc (1) · John A. Baron, MD (1) · M. Peter Lance, MD (1) · Wilbert HM Peters, Ph D (1)
PMID 34289971, PMID 12621133, PMID 17551129, PMID 18541589, PMID 19923375, PMID 20348368, PMID 23919274, PMID 24014734, PMID 24245549, PMID 25070320, PMID 25329821, PMID 26465985, PMID 27094489, PMID 27474021, PMID 27519183, PMID 27683872, PMID 27978548, PMID 28218420, PMID 28767463, PMID 29496722, PMID 31263057, PMID 31401653, PMID 32905675, PMID 33022713, PMID 34261858, PMID 34762658, PMID 36701139
R01CA098286 (1), U10CA037429 (1)