24 unknown, 6 enrolling by invitation, 5 completed, 5 not yet recruiting. 12 Phase 2, 11 Phase 4, 8 Not applicable, 7 Phase 3, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Befotertinib Plus Chemotherapy With an MRD-guided Adaptive Strategy for Treatment Escalation and Response Optimization in EGFR-mutated NSCLC Patients Befotinib, Pemetrexed + Cisplatin /Carboplatin - Advanced Non-small Cell Lung Cancer (NSCLC), EGFR Exon 19 Deletion Mutation | Phase 2 | Not yet recruiting | Guangzhou University of Traditional Chinese Medicine | 124 | 2026-07-05 | 2026-07-16 |
| Chinese Adaptive Randomised Pneumonia Trial With Respiratory Failure Trendelenburg Position, Traditional Chinese Medicine Formulation - Severe Pneumonia With Respiratory Failure | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 1500 | 2026-02-20 | 2026-02-09 |
| Clinical Study on the Early Bactericidal Activity of Contezolid Against Mycobacterium Abscessus Disease Contezolid, linezolid - Monotherapy, Mycobacterium Abscessus Infection | Phase 2 | Enrolling by invitation | Beijing Chest Hospital | 24 | 2026-01-01 | 2026-01-28 |
| A Prospective Multicenter Study of the Association Between TCM Syndromes and EGFR-TKI Efficacy in Lung Cancer Patients EGFR-TKI - Non Small Cell Lung Cancer NSCLC | Not yet recruiting | Guangzhou University of Traditional Chinese Medicine | 3000 | 2026-01-01 | 2026-01-13 | |
| Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BLMZ Chinese Cohort BLMZ - Rifampicin Resistant Tuberculosis, Pulmonary Tuberculosis | Phase 3 | Not yet recruiting | Beijing Chest Hospital | 120 | 2025-12-01 | 2025-12-08 |
| TCM as an Adjuvant Treatment in Mycobacterium Abscessus Pulmonary Disease Chinese herbs-I, Chinese herbs-I placebo, Chinese herbs-II - Mycobacterium Abscessus Pulmonary Disease | Phase 2 | Recruiting | Shanghai University of Traditional Chinese Medicine | 352 | 2025-09-08 | 2025-12-22 |
| Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease Contezolid, Azithromycin, Ethambutol (E) - Mycobacterium Avium Complex Pulmonary Disease | Phase 4 | Recruiting | Bin Cao | 188 | 2025-07-24 | 2025-10-09 |
| Prevention of Recurrence With Cordyceps Sinensis in Mycobacterium Avium Complex Pulmonary Disease cordyceps sinesis capsule, cordyceps sinesis capsule placebo - Mycobacterium Avium Complex Pulmonary Disease | Phase 4 | Recruiting | Bin Cao | 300 | 2025-07-24 | 2025-09-15 |
| Clinical Study on the Early Bactericidal Activity of Sitafloxacin Against Mycobacterium Abscessus Disease Sitafloxacin - Fluoroquinolone, Mycobacterium | Phase 2 | Enrolling by invitation | Beijing Chest Hospital | 12 | 2025-01-28 | 2025-02-05 |
| Phase II Study of Adebrelimab, Chemotherapy, and Apatinib for Advanced Pulmonary Neuroendocrine Tumors Adebrelimab + Apatinib - Neuroendocrine Tumors | Phase 2 | Not yet recruiting | Beijing Chest Hospital | 39 | 2025-01-01 | 2025-01-08 |
| Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese Cohort bedaquiline, delamanid, linezolid - Drug-resistant Tuberculosis, Pulmonary Tuberculosis | Phase 3 | Active not recruiting | Huashan Hospital | 120 | 2024-11-27 | 2025-09-02 |
| The Safety and Efficacy of BDL(Bedaquiline Plus Delamanid Plus Linezolid) Regimen in Subjects With Pulmonary Infection of Multi-drug Resistant Tuberculosis (MDR-TB) or Rifampicin-Resistant Tuberculosis (RR-TB) BDL regimen - Pulmonary Tuberculosis | Phase 4 | Unknown | Beijing Chest Hospital | 45 | 2024-06-01 | 2024-06-26 |
| Phase II Clinical Study of Contezolid for the Treatment of Tuberculous Meningitis Contezolid, Linezolid (LZD) - Tuberculosis, Meningitis | Phase 1 / Phase 2 | Enrolling by invitation | Beijing Chest Hospital | 24 | 2024-02-01 | 2025-02-06 |
| Phase II Clinical Study of Contezolid for the Treatment of Bone and Joint Tuberculosis Contezolid, Linezolid (LZD) - Tuberculosis, Bone | Phase 1 / Phase 2 | Enrolling by invitation | Beijing Chest Hospital | 24 | 2024-01-31 | 2025-02-06 |
| Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort Bedaquiline, Delamanid, Contezolid - Pulmonary Tuberculosis, Rifampicin-resistant Tuberculosis | Phase 3 | Active not recruiting | Beijing Chest Hospital | 186 | 2023-12-22 | 2025-04-01 |
| Clinical Study of JDB0131 Benzenesulfonate Tablets in Patients With Drug-sensitive Pulmonary Tuberculosis JDB0131, Delamanid, Ethylpyrazine rifampicide (II) - Drug-resistant Tuberculosis | Phase 2 | Unknown | Beijing Chest Hospital | 52 | 2023-10-31 | 2024-01-25 |
| Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery Thoracic Paravertebral Block - Postoperative Pulmonary Complications | Not applicable | Completed | Beijing Tongren Hospital | 302 | 2023-07-01 | 2024-08-09 |
| Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis BaiDiZiYin Pill, ShenQiYiFei Pill, Anti tuberculosis chemotherapy - Adjuvant, Treatment | Phase 4 | Recruiting | Beijing Chest Hospital | 292 | 2023-05-29 | 2024-05-08 |
| Effect of Compound Amino Acid Tablets on Nutritional Status of Patients With Lung Cancer amino acid tablet - Amino Acid Deficiency, Malnutrition | Not applicable | Unknown | Beijing Chest Hospital | 86 | 2023-04-15 | 2023-03-15 |
| Surufatinib in Combination of Durvalumab and EP/EC in the Firstly-line Treatment of ES-SCLC Surufatinib Durvalizumab EP/EC - Extensive-stage Small-cell Lung Cancer | Phase 2 | Unknown | Beijing Chest Hospital | 20 | 2022-12-01 | 2022-12-30 |
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Tuberculosis (11) · Carcinoma, Non-Small-Cell Lung (7) · Tuberculosis, Pulmonary (7) · Tuberculosis, Multidrug-Resistant (6) · Lung Neoplasms (5) · Mycobacterium Infections, Nontuberculous (3) · Small Cell Lung Carcinoma (3) · Tuberculosis, Meningeal (3) · Adenocarcinoma of Lung (1) · Bronchial Neoplasms (1) · Cancer Pain (1) · Carcinoma, Bronchogenic (1) · Malnutrition (1) · Meningitis (1) · Mycobacterium Infections (1)
Linezolid (6) · Ethambutol (5) · contezolid (5) · Isoniazid (4) · Levofloxacin (4) · OPC-67683 (4) · Pyrazinamide (4) · Rifampin (4) · Clofazimine (3) · apatinib (3) · bedaquiline (3) · Cycloserine (2) · Prothionamide (2) · Amino Acids (1) · Aminosalicylic Acid (1)
China (35)
Guyan Wang (1) · Hongfei Duan, MD (1) · Hongqiu Pan (1) · Juwei Mu, MD (1) · Li Baolan (1) · Li Zhang, PhD (1) · Liang Li (1) · Mengqiu Gao (1) · Mengqiu Gao, Ph.D (1) · Naihui Chu, Bachelor (1) · Naihui Chu, PhD (1) · Qi Wu, Master (1) · Qinfang Ou (1) · Qunyi Deng, Doctor (1)
PMID 11965272, PMID 16631680, PMID 16824243, PMID 17008692, PMID 21296855, PMID 23902482, PMID 25389025, PMID 25913824, PMID 26197368, PMID 26796810, PMID 26897642, PMID 27160473, PMID 27955978, PMID 28248713, PMID 28399802, PMID 28412111, PMID 28629333, PMID 29121283, PMID 29174310, PMID 29253106, PMID 29763594, PMID 31144301, PMID 31516902, PMID 32030234, PMID 32143570, PMID 33183325, PMID 33332190, PMID 33410611, PMID 33635945, PMID 33687175, PMID 33814927, PMID 34033322, PMID 35020204, PMID 35334289, PMID 38254233, PMID 38561815, PMID 40421698, PMID 41090140, PMID 41419836, PMID 41461639, PMID 41925982