20 completed. 20 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 20 |
| Phase 2 | 1 | Completed 1 |
Follow Abscess: new trials by email Literature Review of Abscess trials Research Report on Abscess
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Fentanyl as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage Intranasal fentanyl, Placebo - Abscess | Phase 3 | Completed | Montefiore Medical Center | 49 | 2019-08-01 | 2023-08-15 |
| Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy Neem leaf extract, Chlorhexidine gluconate - Periapical Abscess | Phase 2 / Phase 3 | Completed | Cairo University | 40 | 2016-12-01 | 2019-07-31 |
| Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Dalbavancin, Dalbavancin-matching Placebo - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 698 | 2014-04-18 | 2018-09-28 |
| Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa adalimumab - Hidradenitis Suppurativa | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 508 | 2012-04-01 | 2018-01-24 |
| Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children Intranasal Fentanyl, Intravenous Morphine - Abscess, Pain | Phase 3 | Completed | Columbia University | 20 | 2012-01-01 | 2019-04-30 |
| Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections IV Dalbavancin, Vancomycin/Linezolid - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 739 | 2011-07-01 | 2014-02-12 |
| Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Dalbavancin, Vancomycin / Linezolid - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 573 | 2011-03-01 | 2014-01-31 |
| Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I) Single-Dose IV Oritavancin Diphosphate, IV Vancomycin, Placebo - Wound Infection, Abscess | Phase 3 | Completed | Melinta Therapeutics, Inc. | 968 | 2010-12-01 | 2022-08-01 |
| Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection Single-Dose IV Oritavancin Diphosphate, IV Vancomycin - Wound Infection, Abscess | Phase 3 | Completed | Melinta Therapeutics, Inc. | 1019 | 2010-12-01 | 2021-05-05 |
| Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery Intra-peritoneal antibiotic lavage - Surgical Site Infection | Phase 3 | Completed | Universidad Miguel Hernandez de Elche | 102 | 2010-01-01 | 2011-06-22 |
| Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses Incision and Drainage, Ultrasound Guided Aspiration - Abscess, Cellulitis | Phase 3 | Completed | University of Massachusetts, Worcester | 101 | 2008-08-01 | 2010-03-12 |
| Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage oral trimethoprim/sulfamethoxazole, Placebo - Abscess | Phase 3 | Completed | Baylor College of Medicine | 23 | 2007-12-01 | 2020-07-01 |
| Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses bactrim, placebo - Abscesses | Phase 3 | Completed | 59th Medical Wing | 212 | 2007-11-01 | 2010-03-09 |
| Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections ceftaroline, vancomycin plus aztreonam, Placebo - Bacterial Infections | Phase 3 | Completed | Forest Laboratories | 680 | 2007-03-01 | 2017-03-14 |
| Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections IV Vancomycin plus IV Aztreonam, Ceftaroline - Bacterial Infections | Phase 3 | Completed | Forest Laboratories | 698 | 2007-02-01 | 2017-03-14 |
| Comparison of Sequential IV/PO Moxifloxacin With IV Piperacillin/Tazobactam Followed by PO Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure Infection Moxifloxacin (Avelox, BAY12-8039), Piperacillin/Tazobactam & Amoxicillin/Clavulanic acid - Abscess, Wound Infection | Phase 3 | Completed | Bayer | 813 | 2006-09-01 | 2014-11-07 |
| Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses Moxifloxacin/Metronidazole or Piperacillin/Tazobactam - Abscess, Intra-Abdominal | Phase 3 | Completed | Hannover Medical School | 180 | 2005-11-15 | 2018-07-24 |
| Study Comparing Tigecycline and Imipenem/Cilastatin in Chinese Subjects With Complicated Intra-Abdominal Infections tigecycline - Abdominal Abscess | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 200 | 2005-11-01 | 2009-07-07 |
| BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia Avelox (Moxifloxacin, BAY12-8039), Sulbactam/Ampicillin - Pneumonia, Aspiration, Lung Abscess | Phase 3 | Completed | Bayer | 139 | 2001-02-01 | 2010-01-11 |
| Complicated Skin and Skin Structure Infections Meropenem, Imipenem-cilastatin - Skin Infection, Abscess | Phase 3 | Completed | Pfizer | 1000 | 2001-02-01 | 2017-09-01 |
Cellulitis (10) · Wound Infection (8) · Surgical Wound Infection (6) · Abdominal Abscess (3) · Bacterial Infections (2) · Skin Diseases, Bacterial (2) · Staphylococcal Infections (2) · Staphylococcal Skin Infections (2) · Acne Vulgaris (1) · Community-Acquired Infections (1) · Cross Infection (1) · Diabetic Foot (1) · Hidradenitis Suppurativa (1) · Infections (1)
Suppuration (20) · Infections (19) · Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Inflammation (16) · Skin and Connective Tissue Diseases (12) · Skin Diseases, Infectious (11) · Connective Tissue Diseases (10) · Postoperative Complications (6) · Skin Diseases (4) · Bacterial Infections and Mycoses (3) · Gram-Positive Bacterial Infections (2) · Wound Infection (2) · Acneiform Eruptions (1)
Vancomycin (6) · Moxifloxacin (3) · dalbavancin (3) · Aztreonam (2) · Ceftaroline (2) · Linezolid (2) · Trimethoprim, Sulfamethoxazole Drug Combination (2) · Adalimumab (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Cilastatin, Imipenem Drug Combination (1) · Drainage (1) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Fentanyl (1) · Meropenem (1) · Metronidazole (1)
Durata Therapeutics Inc., an affiliate of Allergan plc (3) · Bayer (2) · Forest Laboratories (2) · Melinta Therapeutics, Inc. (2) · 59th Medical Wing (1) · AbbVie (prior sponsor, Abbott) (1) · Baylor College of Medicine (1) · Cairo University (1) · Columbia University (1) · Hannover Medical School (1) · Montefiore Medical Center (1) · Pfizer (1) · Universidad Miguel Hernandez de Elche (1) · University of Massachusetts, Worcester (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
United States (12) · Germany (6) · Russia (6) · Ukraine (6) · Latvia (4) · Poland (4) · Romania (4) · Bulgaria (3) · Hungary (3) · South Africa (3) · Argentina (2) · Austria (2) · Brazil (2) · Chile (2) · Croatia (2)
G. Ralph Corey, MD (2) · Michael Dunne, MD (2) · Andrea Cruz, MD, MPH (1) · Benjamin Friedman, MD (1) · Dalia M Moheb, Assoc Prof (1) · Daniel Fenster, MD (1) · Daniel Tsze, MD, MPH (1) · Mark Wilcox, MD (1) · Michael Winkler, Prof (1) · Norhan A El Dokky, Assoc Prof (1) · Peter Dayan, MD, MSc (1) · Ralph Corey, MD (1)
PMID 34905144, PMID 20695801, PMID 21115456, PMID 24897082, PMID 27370913, PMID 29358292, PMID 30597021, PMID 30716446, PMID 34741280, PMID 34922058, PMID 19036670, PMID 20346539, PMID 20663130, PMID 21115454, PMID 21115455, PMID 21896561, PMID 22265220, PMID 23180507, PMID 24897083, PMID 25294250, PMID 26611777, PMID 27387971, PMID 30797084, PMID 31786695