20 completed, 4 terminated, 3 unknown, 2 recruiting. 31 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 31 | Completed 20, Terminated 4, Unknown 3, Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
Follow Abscess: new trials by email Literature Review of Abscess trials Research Report on Abscess
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Diloxanide Furoate as Additional Luminal Agent Along With Metronidazole for the Treatment of Amoebic Liver Abscess Diloxanide furoate, Placebo - Liver Abscess, Amoebic Liver Abscess | Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 220 | 2026-09-04 | 2026-09-10 |
| Empirical Intravenous Beta-Lactam Plus Metronidazole Vs Oral Cefixime Plus Metronidazole for the Treatment of Liver Abscess Intravenous beta-lactam antimicrobial for 2 weeks Plus Intravenous Metronidazole (750 mg q 8 hourly) for 2 weeks, Tablet Cefixime (200 mg q 12 hourly) for 2 weeks Plus Tablet Metronidazole (800 mg q 8 hourly) for 2 weeks, Standard medical care - Liver Abscess | Phase 3 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 220 | 2025-02-25 | 2025-04-13 |
| Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis Laparoscopic antibiotic peritoneal lavage with gentamicin / clindamycin - Complicated Appendicitis, Intra-Abdominal Abscess | Phase 3 | Recruiting | Spaarne Gasthuis | 752 | 2025-02-24 | 2026-10-09 |
| Intranasal Fentanyl as an Adjunct to Lidocaine Infiltration in Adults Undergoing Abscess Incision and Drainage Intranasal fentanyl, Placebo - Abscess | Phase 3 | Completed | Montefiore Medical Center | 49 | 2019-08-01 | 2023-08-15 |
| Ciprofloxacin Plus Metronidazole Vs Cefixime Plus Metronidazole Therapy for the Treatment of Liver Abscess Ciprofloxacin, Cefixime - Liver Abscess | Phase 3 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 140 | 2019-07-01 | 2019-07-22 |
| Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant root canal treatment and intracanal medicament - Periapical Abscess | Phase 2 / Phase 3 | Unknown | Dr. D. Y. Patil Dental College & Hospital | 40 | 2018-12-03 | 2020-03-24 |
| Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy Neem leaf extract, Chlorhexidine gluconate - Periapical Abscess | Phase 2 / Phase 3 | Completed | Cairo University | 40 | 2016-12-01 | 2019-07-31 |
| Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Dalbavancin, Dalbavancin-matching Placebo - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 698 | 2014-04-18 | 2018-09-28 |
| Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa adalimumab - Hidradenitis Suppurativa | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 508 | 2012-04-01 | 2018-01-24 |
| Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study Cathflo (Alteplase), Saline - Intra-abdominal Abscess | Phase 3 | Terminated | The Hospital for Sick Children | 28 | 2012-03-01 | 2019-06-27 |
| Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children Intranasal Fentanyl, Intravenous Morphine - Abscess, Pain | Phase 3 | Completed | Columbia University | 20 | 2012-01-01 | 2019-04-30 |
| Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer Stapled anastomosis, Handsewn anastomosis - Peritoneal Contamination After Ileocolonic Anastomosis, Wound Infection | Phase 3 | Unknown | Hospital General Universitario Elche | 80 | 2011-11-01 | 2011-10-24 |
| Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections IV Dalbavancin, Vancomycin/Linezolid - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 739 | 2011-07-01 | 2014-02-12 |
| Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Dalbavancin, Vancomycin / Linezolid - Abscess, Wound Infection | Phase 3 | Completed | Durata Therapeutics Inc., an affiliate of Allergan plc | 573 | 2011-03-01 | 2014-01-31 |
| Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I) Single-Dose IV Oritavancin Diphosphate, IV Vancomycin, Placebo - Wound Infection, Abscess | Phase 3 | Completed | Melinta Therapeutics, Inc. | 968 | 2010-12-01 | 2022-08-01 |
| A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections Doripenem, Meropenem placebo, Meropenem - Abscess, Intra-Abdominal, Abdominal Abscess | Phase 3 | Terminated | Janssen Research & Development, LLC | 41 | 2010-12-01 | 2014-07-15 |
| Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection Single-Dose IV Oritavancin Diphosphate, IV Vancomycin - Wound Infection, Abscess | Phase 3 | Completed | Melinta Therapeutics, Inc. | 1019 | 2010-12-01 | 2021-05-05 |
| Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery Intra-peritoneal antibiotic lavage - Surgical Site Infection | Phase 3 | Completed | Universidad Miguel Hernandez de Elche | 102 | 2010-01-01 | 2011-06-22 |
| Phase 3 Study - Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI) PTK 0796, Linezolid - Skin Structures and Soft Tissue Infections | Phase 3 | Withdrawn | Paratek Pharmaceuticals Inc | 2009-07-01 | 2012-05-09 | |
| Study the Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI) PTK 0796, linezolid, moxifloxacin - Skin Diseases, Infectious | Phase 3 | Terminated | Paratek Pharmaceuticals Inc | 143 | 2009-04-04 | 2021-03-12 |
Showing 20 of 31. Sign in to see all of them.
Cellulitis (12) · Wound Infection (9) · Abdominal Abscess (7) · Surgical Wound Infection (6) · Liver Abscess (3) · Bacterial Infections (2) · Infections (2) · Periapical Abscess (2) · Peritonitis (2) · Skin Diseases, Bacterial (2) · Staphylococcal Infections (2) · Staphylococcal Skin Infections (2) · Abdomen, Acute (1) · Abdominal Pain (1)
Suppuration (31) · Infections (29) · Pathological Conditions, Signs and Symptoms (23) · Pathologic Processes (22) · Inflammation (20) · Skin and Connective Tissue Diseases (14) · Connective Tissue Diseases (12) · Skin Diseases, Infectious (12) · Postoperative Complications (6) · Digestive System Diseases (5) · Skin Diseases (5) · Abdominal Abscess (3) · Bacterial Infections and Mycoses (3) · Liver Diseases (3)
Vancomycin (6) · Moxifloxacin (5) · Linezolid (4) · dalbavancin (3) · 7-dimethylamino-9-(2,2-dimethylpropyl)aminomethylcycline (2) · Amoxicillin-Potassium Clavulanate Combination (2) · Aztreonam (2) · Ceftaroline (2) · Meropenem (2) · Metronidazole (2) · Tissue Plasminogen Activator (2) · Trimethoprim, Sulfamethoxazole Drug Combination (2) · Adalimumab (1) · Cefixime (1) · Cilastatin, Imipenem Drug Combination (1)
Durata Therapeutics Inc., an affiliate of Allergan plc (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · Bayer (2) · Forest Laboratories (2) · Melinta Therapeutics, Inc. (2) · Paratek Pharmaceuticals Inc (2) · 59th Medical Wing (1) · AbbVie (prior sponsor, Abbott) (1) · Baylor College of Medicine (1) · Cairo University (1) · Columbia University (1) · Dr. D. Y. Patil Dental College & Hospital (1) · Hannover Medical School (1) · Hospital General Universitario Elche (1) · Janssen Research & Development, LLC (1)
United States (14) · Germany (6) · Russia (6) · Ukraine (6) · Latvia (5) · India (4) · Poland (4) · Romania (4) · Argentina (3) · Brazil (3) · Bulgaria (3) · Canada (3) · Chile (3) · Hungary (3) · Lithuania (3)
G. Ralph Corey, MD (2) · Michael Dunne, MD (2) · Andrea Cruz, MD, MPH (1) · Antonio Arroyo, MD, PhD (1) · Bairbre Connolly, MD (1) · Benjamin Friedman, MD (1) · Dalia M Moheb, Assoc Prof (1) · Daniel Fenster, MD (1) · Daniel Tsze, MD, MPH (1) · Deba P Dhibar, MD (1) · Dheeraj Rajan, MD (1) · Jaime Ruiz-Tovar, MD, PhD (1)
PMID 34905144, PMID 20695801, PMID 21115456, PMID 24897082, PMID 27370913, PMID 29358292, PMID 30597021, PMID 30716446, PMID 34741280, PMID 34922058, PMID 19036670, PMID 20346539, PMID 20663130, PMID 21115454, PMID 21115455, PMID 21896561, PMID 22265220, PMID 22581209, PMID 23180507, PMID 24897083, PMID 25294250, PMID 26611777, PMID 27387971, PMID 30797084, PMID 31786695, PMID 38769330
2009 (1)