7 completed, 2 unknown, 1 terminated. 10 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 7, Unknown 2, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow Abdominal Surgery: new trials by email Literature Review of Abdominal Surgery trials Research Report on Abdominal Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dalargin for Prevention of Organ Disfunction in High-Risk Abdominal Surgery Dalargin, 0.9 % NaCl - Postoperative Complications, Multiple Organ Failure | Phase 3 | Completed | Botkin Hospital | 200 | 2025-05-13 | 2026-09-23 |
| Opioid Free Anesthesia in Abdominal Laparoscopic Surgery Dexmedetomidine, Fentanyl - Laparoscopic Surgery, Abdominal Surgery | Phase 2 / Phase 3 | Completed | Universitas Indonesia | 74 | 2023-07-01 | 2024-05-03 |
| Comparing TAP Blocks Bupivacaine, and Placebo for Plane Liposomal bupivacaine, Plain bupivacaine, Normal saline - Abdominal Surgery | Phase 3 | Completed | Edward Mascha | 285 | 2021-06-04 | 2025-08-27 |
| D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II) D-PLEX, Standard of Care (SoC) - Surgical Site Infection, Colon Surgery | Phase 3 | Completed | PolyPid Ltd. | 975 | 2020-12-15 | 2026-07-13 |
| D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection D-PLEX, Standard of Care (SoC) - Surgical Site Infection, Colon Surgery | Phase 3 | Completed | PolyPid Ltd. | 977 | 2020-06-24 | 2026-04-21 |
| Pilot Trial: Postoperative Opioid-free Analgesia Opioid analgesics, Non-opioid analgesics - Outpatient Surgery, Abdominal Surgery | Phase 2 / Phase 3 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 81 | 2020-01-29 | 2024-11-20 |
| FALCON Trial Testing Measures to Reduce Surgical Site Infection 2% chlorhexidine + non-coated suture, 2% chlorhexidine + coated suture, 10%povidone-iodine + non-coated suture - Abdominal Surgery, Surgical Site Infection | Phase 3 | Unknown | University of Birmingham | 5480 | 2018-11-29 | 2019-09-26 |
| Bupivacaine Effectiveness and Safety in SABER® Trial SABER-Bupivacaine, Bupivacaine HCl, SABER-Placebo - Postoperative Pain, Abdominal Surgery | Phase 3 | Completed | Durect | 331 | 2009-12-01 | 2021-06-01 |
| Study To Check The Analgesic And Anti-Inflammatory Effects Of Atorvastatin In Patients Undergoing Abdominal Surgery Atorvastatin, Placebo - Abdominal Surgery | Phase 3 | Unknown | B. J. Medical College, Pune | 40 | 2009-07-01 | 2009-06-03 |
| Etoricoxibe - Preemptive and Postoperative Analgesia for Abdominal and Thoracic Surgery Etoricoxibe, Placebo - Pain, Abdominal Surgery | Phase 3 | Terminated | Ludwig-Maximilians - University of Munich | 87 | 2006-02-01 | 2015-01-16 |
Pain, Postoperative (3) · Surgical Wound Infection (3) · Agnosia (2) · Multiple Organ Failure (1) · Pain (1) · Postoperative Complications (1) · Spinocerebellar ataxia 23 (1)
Pathological Conditions, Signs and Symptoms (8) · Pathologic Processes (7) · Postoperative Complications (6) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Infections (3) · Pain (3) · Wound Infection (3) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Shock (1)
Saline Solution (2) · Standard of Care (2) · Analgesics, Non-Narcotic (1) · Analgesics, Opioid (1) · Atorvastatin (1) · Bupivacaine (1) · Chlorhexidine (1) · Dexmedetomidine (1) · Fentanyl (1) · Sodium Chloride (1) · enkephalin-Leu, Ala(2)-Arg(6)- (1)
PolyPid Ltd. (2) · B. J. Medical College, Pune (1) · Botkin Hospital (1) · Durect (1) · Edward Mascha (1) · Ludwig-Maximilians - University of Munich (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Universitas Indonesia (1) · University of Birmingham (1)
United States (4) · Germany (2) · Hungary (2) · Israel (2) · Moldova (2) · Poland (2) · Romania (2) · Australia (1) · Bosnia and Herzegovina (1) · Bulgaria (1) · Canada (1) · Croatia (1) · Czechia (1) · Georgia (1) · India (1)
Alparslan Turan, MD (1) · Dion Morton (1) · Dmitri Lissin, MD (1) · Dominik Irnich, PD. Dr. (1) · Shmuel Sharoni, MD (1)
PMID 25828692, PMID 34710362, PMID 35849399, PMID 36328045, PMID 37086854, PMID 38747515, PMID 39245053, PMID 41329063