4 completed, 2 recruiting. 6 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Recruiting 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The ASPIRE Trial: AchilleS tendinoPathy Treated With cortIcosteRoid injEctions Standard care, Depo-Medrol (methylprednisolone acetate 40 mg) combined with lidocaine, placebo injections consisting of lidocaine only - Achilles Tendinopathy (AT) | Phase 3 | Recruiting | Erasmus Medical Center | 276 | 2026-06-03 | 2026-06-18 |
| Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery Nizaracianine Triflutate, Placebo Comparator - Injury of Ureter During Surgery (Disorder) | Phase 2 / Phase 3 | Recruiting | Curadel Surgical Innovations, Inc. | 336 | 2024-06-28 | 2026-02-23 |
| Reduced Anticoagulation Targets in ECLS (RATE) Heparin, LMWH - Heart Failure, Respiratory Failure | Phase 3 | Completed | University Medical Center Groningen | 330 | 2020-10-01 | 2025-05-02 |
| Effect Study of Modified Transoesophageal Echocardiography on Cerebral Embolization After Cardiothoracic Surgery A-View - Coronary Artery Atherosclerosis | Phase 3 | Completed | Isala | 32 | 2011-03-01 | 2012-08-09 |
| Haemocomplettan® P During Elective Complex Cardiac Surgery Haemocomplettan® P, Human albumin (Placebo) - Fibrinogen Deficiency in Complex Cardiac Surgery | Phase 2 / Phase 3 | Completed | Isala | 120 | 2011-02-01 | 2014-12-16 |
| The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough azithromycin, placebo - Cough, Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | Isala | 84 | 2009-09-01 | 2015-09-18 |
Bronchitis, Chronic (1) · Chronic Cough (1) · Coronary Artery Disease (1) · Cough (1) · Heart Failure (1) · Hemorrhage (1) · Hemostatic Disorders (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Insufficiency (1) · Thrombosis (1)
Albumins (1) · Azithromycin (1) · Enoxaparin (1) · Fibrinogen (1) · Heparin (1) · Heparin, Low-Molecular-Weight (1) · Lidocaine (1) · Methylprednisolone Acetate (1) · Nadroparin (1) · Serum Albumin, Human (1) · Standard of Care (1) · Sugars (1) · ZW800-1 compound (1)
Netherlands (5) · United States (1)
Alexander L Vahrmeijer, M.D., Ph.D (1) · Arno Nierich, MD, PhD (1) · Arno P Nierich, MD, PhD. (1) · John V Frangioni, M.D., Ph.D. (1) · Robert Jan de Vos, MD, PhD (1) · W.M. van den Bergh, PhD, MD (1)
PMID 22230731, PMID 24229360, PMID 28241354, PMID 35578271, PMID 40087802, PMID 41527181, PMID 42413523
2019 (1), 2025 (1)