55 completed, 23 recruiting, 17 unknown, 4 active not recruiting. 43 Not applicable, 17 Phase 4, 7 Phase 2, 6 Phase 3, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial Phototherapy, Exchange Transfusion - Neonatal Hyperbilirubinemia, Treatment Decisions | Not applicable | Not yet recruiting | University Medical Center Groningen | 680 | 2026-08-01 | 2026-06-29 |
| The ASPIRE Trial: AchilleS tendinoPathy Treated With cortIcosteRoid injEctions Standard care, Depo-Medrol (methylprednisolone acetate 40 mg) combined with lidocaine, placebo injections consisting of lidocaine only - Achilles Tendinopathy (AT) | Phase 3 | Recruiting | Erasmus Medical Center | 276 | 2026-06-03 | 2026-06-18 |
| CGM in Acute Ischemic Stroke Continuous Glucose Monitoring, Point-of-Care Testing - Acute Ischemic Stroke, Diabetes (DM) | Not applicable | Not yet recruiting | Isala | 82 | 2026-04-01 | 2026-04-06 |
| Correlation of Diaphragm Shear-Wave Elastography With Transdiaphragmatic Pressure in Healthy Adults: a Feasibility Study shear wave elastography of the diaphragm - Diaphragm Ultrasound, Diaphragm Dysfunction | Not yet recruiting | Isala | 12 | 2026-04-01 | 2025-12-05 | |
| Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation IMPROVE Risk Model - Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction | Not applicable | Recruiting | Maastricht University Medical Center | 613 | 2026-03-31 | 2026-05-15 |
| Ultrasound of the Diaphragm Excursion Ratio as Physiological Biomarker in Acute Exacerbations of Chronic Obstructive Pulmonary Disease COPD | Recruiting | Isala | 186 | 2025-10-14 | 2025-12-02 | |
| Early Mindfulness Based Cognitive Therapy for Prevention of Psychological Distress in Cancer Patients Mindfulness based stress reduction - Cancer, Mindfulness Based Cognitive Therapy | Not applicable | Not yet recruiting | Isala | 208 | 2025-10-01 | 2025-08-15 |
| Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) HOP bundle - Pancreas Head Cancer, Pancreas Adenocarcinoma | Phase 4 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 400 | 2025-09-01 | 2025-12-22 |
| Poly vs Hybrid Glenoid in Stemless aTSA Anatomic total shoulder arthroplasty with cemented all-polyethylene pegged glenoid, Anatomic total shoulder arthroplasty with hybrid trabecular titanium central-peg glenoid - Glenohumeral Osteoarthritis | Not applicable | Recruiting | Spaarne Gasthuis | 94 | 2025-06-30 | 2026-04-09 |
| Telemedicine Follow-Up for Early Laryngeal Cancer: a Randomized Controlled Trial Comparing Care Close to Home Versus Standard of Care Telemedicine Follow-up - Head and Neck Cancers, Laryngeal Carcinoma | Not applicable | Recruiting | University Medical Center Groningen | 140 | 2025-04-01 | 2025-08-19 |
| Prevention of PostAmputation Pain With Targeted Muscle Reinnervation Targeted Muscle Reinnervation (TMR), Standard neurectomy - Amputation, Surgical, Phantom Limb Pain | Not applicable | Recruiting | Leiden University Medical Center | 203 | 2024-12-31 | 2025-09-19 |
| Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery Nizaracianine Triflutate, Placebo Comparator - Injury of Ureter During Surgery (Disorder) | Phase 2 / Phase 3 | Recruiting | Curadel Surgical Innovations, Inc. | 336 | 2024-06-28 | 2026-02-23 |
| Hip Socket Erosion Study Femoral Neck Fractures, Hemiarthroplasty | Completed | Rijnstate Hospital | 134 | 2024-06-19 | 2026-06-25 | |
| Potassium Correction for RAAS Optimization in Chronic Kidney Disease Patiromer 8400 MG [Veltassa], Placebo - Chronic Kidney Diseases, Hyperkalemia | Phase 4 | Recruiting | University Medical Center Groningen | 44 | 2024-04-01 | 2025-12-19 |
| Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH) Total Hip Arthroplasty - Osteoarthritis, Hip | Not applicable | Recruiting | Isala | 211 | 2024-03-26 | 2025-08-03 |
| Multicenter Registry of Patients With Subarachnoid Hemorrhage None, observational study - Subarachnoid Hemorrhage, Spontaneous | Recruiting | UMC Utrecht | 1000 | 2024-02-12 | 2026-03-19 | |
| Effectiveness of Focal Therapy in Men With Prostate Cancer Focal therapy, Usual care - Prostate Cancer, Prostate Neoplasm | Not applicable | Recruiting | Radboud University Medical Center | 356 | 2024-02-01 | 2024-02-20 |
| Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages Prednisolone, Placebo - Recurrent Miscarriage, Recurrent Pregnancy Loss | Phase 4 | Recruiting | Leiden University Medical Center | 490 | 2024-01-29 | 2024-05-24 |
| Driving Pressure During General Anesthesia for Minimally Invasive Abdominal Surgery (GENERATOR) Intraoperative ventilation with individualized high PEEP titrated to the lowest ΔP with RMs - Postoperative Complications, Surgery | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 1806 | 2023-12-11 | 2025-01-30 |
| Ultrasound as Diagnostic Tool in Diaphragm Dysfunction ultrasound of the diaphragm - Diaphragm Disease | Completed | Isala | 36 | 2023-09-05 | 2024-06-21 |
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Pulmonary Disease, Chronic Obstructive (7) · Neoplasms (6) · Lung Neoplasms (5) · Coronary Artery Disease (4) · Diabetes Mellitus (4) · Pain (4) · Breast Neoplasms (3) · Kidney Failure, Chronic (3) · Osteoarthritis (3) · Pancreatic Neoplasms (3) · ST Elevation Myocardial Infarction (3) · Bone Neoplasms (2) · Cardiovascular Diseases (2) · Cough (2) · Delirium (2)
Surveys and Questionnaires (5) · Interviews as Topic (2) · Prednisolone (2) · Radiotherapy (2) · atezolizumab (2) · Acetaminophen (1) · Albumins (1) · Arthroplasty, Replacement (1) · Arthroplasty, Replacement, Hip (1) · Azithromycin (1) · Bevacizumab (1) · Carboplatin (1) · Clindamycin (1) · Clopidogrel (1) · Cognitive Behavioral Therapy (1)
Netherlands (91) · Belgium (4) · Italy (3) · Germany (2) · Denmark (1) · Finland (1) · Lithuania (1) · Norway (1) · Sweden (1) · Switzerland (1) · United States (1)
Jeroen H. van Uchelen, MD (2) · Marije Hogeveen, MD, PhD (2) · A A. Franken, MD PhD (1) · A W Nap, MSc, PhD (1) · A.F. Muller, MD, PhD (1) · Aaltje Adema, dr. (1) · Alexander L Vahrmeijer, M.D., Ph.D (1) · Arno Hoes, Prof. MD PhD (1) · Arno Nierich, MD, PhD (1) · Arno P Nierich, MD, PhD. (1) · B. Havekes, MD, PhD (1) · B.J. Cohlen, MD/PhD (1) · Bart CJ Fauser, MD PhD (1)
PMID 12699951, PMID 14656913, PMID 17309907, PMID 17331245, PMID 17646228, PMID 18551082, PMID 19066296, PMID 20395876, PMID 20413516, PMID 21249647, PMID 21316664, PMID 22230731, PMID 22559239, PMID 22792314, PMID 22925840, PMID 23590389, PMID 23881033, PMID 24229360, PMID 24593656, PMID 26542508, PMID 26682232, PMID 26824223, PMID 26947523, PMID 28138958, PMID 28241354, PMID 29298669, PMID 29636042, PMID 29739430, PMID 30579407, PMID 31066709, PMID 31479209, PMID 31650393, PMID 31675925, PMID 31714582, PMID 31823097, PMID 32070400, PMID 32334703, PMID 33295981, PMID 33461579, PMID 33627317, PMID 33722066, PMID 33998271, PMID 34064948, PMID 34258321, PMID 34345911, PMID 34347140, PMID 34392637, PMID 34490590, PMID 34729767, PMID 34880026
2014 (1), 2017 (1), 2019 (1), 2023 (1), 2025 (1)